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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:14 PM EDT

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Showing 73–96 of 365 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-Compulsive Disorder Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

NCT01919970
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 19, 2026, 8:14 PM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

NCT04131829
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Fluoxetine - immediate treatment, Fluoxetine - delayed treatment
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational

Psychosocial, Behavioral, and Radiologic Changes Following Radiosurgery for Benign Neurologic Disease

NCT04688554
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Pain, Intractable, Depression
Interventions
fMRI and DTI, Behavioral questionnaires, Disease-Specific Patient-Reported Outcomes, Behavioral tests
Diagnostic Test · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

NCT00748761
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive Behavioral Therapy (CBT), Waitlist
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Years to 18 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study

NCT02573246
View directory record Official record
Conditions
Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders, Somatic Disorders, Obsessive Compulsive Disorders, Eating Disorders, Difficulties With Cognitive Emotion Regulation
Interventions
Cognitive Restructuring, rTMS, Sham rTMS
Behavioral · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 19, 2026, 8:14 PM EDT
Withdrawn Phase 2 Interventional

Trial of Low-Dose Xenon For The Treatment Of Obsessive-Compulsive Disorder

NCT02098148
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Xenon, Placebo
Drug
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2014 · Synced Oct 19, 2026, 8:14 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)

NCT07566468
View directory record Official record
Conditions
ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
10 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Not yet recruiting Not applicable Interventional

A Test of Acceptance-based Bibliotherapy for Hoarding Disorder

NCT07880236
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Acceptance and Commitment Therapy Bibliotherapy
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Syracuse, New York • Logan, Utah
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Active, not recruiting Not applicable Interventional

Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder

NCT03511534
View directory record Official record
Conditions
OCD
Interventions
Psychotherapy, Pharmacotherapy
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Marijuana on Symptoms of OCD

NCT03274440
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cannabis, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional Results available

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

NCT00956085
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Memantine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 19, 2026, 8:14 PM EDT
Recruiting No phase listed Observational

Developing Brain, Impulsivity and Compulsivity

NCT04631042
View directory record Official record
Conditions
Typical Development, Obsessive Compulsive Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
6 Years to 80 Years
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 4 Interventional

Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania

NCT00118014
View directory record Official record
Conditions
Impulse Control Disorders
Interventions
Sertraline, Habit Reversal Training
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2008 · Synced Oct 19, 2026, 8:14 PM EDT
Active, not recruiting Not applicable Interventional

Individualized Neuroimaging Biomarkers for Predicting rTMS Response in OCD

NCT05829681
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

An Open-Label Study Of Lamictal In Neurotic Excoriation

NCT00269594
View directory record Official record
Conditions
Neurotic Disorders, Obsessive-Compulsive Disorder
Interventions
Lamictal (lamotrigine)
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2007 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Skin Picking Approach Avoidance Task

NCT04099537
View directory record Official record
Conditions
Skin-Picking
Interventions
Computerized cognitive training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 28, 2022 · Synced Oct 19, 2026, 8:14 PM EDT
Terminated Phase 1 Interventional

A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline

NCT05189977
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD)
Interventions
Propranolol, Prazosin
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 19, 2026, 8:14 PM EDT
Suspended Phase 2 Interventional

Neuroinflammation in Patients With OCD

NCT04786548
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Celecoxib
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational

Study of the Neurobiology of Tourette Syndrome and Related Disorders

NCT00004325
View directory record Official record
Conditions
Tourette Syndrome, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
12 Years to 45 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1988
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 19, 2026, 8:14 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation

NCT02704117
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magentic Stimulation
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 4 Interventional

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome

NCT05657860
View directory record Official record
Conditions
Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking
Interventions
Guanfacine Extended Release, Placebo
Drug · Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
6 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 19, 2026, 8:14 PM EDT
Completed No phase listed Observational

Antidepressant Safety in Kids Study

NCT00395213
View directory record Official record
Conditions
Anxiety Disorders, Depressive Disorders, Eating Disorders, Obsessive Compulsive Disorder
Interventions
Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications
Drug
Lead sponsor
Duke University
Other
Eligibility
7 Years to 17 Years
Enrollment
569 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2015 · Synced Oct 19, 2026, 8:14 PM EDT
Completed Phase 2 Interventional Results available

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

NCT01695291
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Minocycline, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
8 Years to 20 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 19, 2026, 8:14 PM EDT