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ClinicalTrials.gov public records Last synced Oct 7, 2026, 7:45 AM EDT

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Showing 265–288 of 362 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-Compulsive Disorder (OCD) Clear all
Withdrawn No phase listed Observational

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obsessive-Compulsive Disorder

NCT04211402
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
No Intervention
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 4 Interventional

Escitalopram for the Treatment of Self-Injurious Skin Picking

NCT00115011
View directory record Official record
Conditions
Impulse Control Disorders
Interventions
Escitalopram
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2008 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional

Assisting Obsessive Compulsive Disorder (OCD) Patients With Discontinuing Long-term Serotonin Reuptake Inhibitors (SRIs)

NCT02103621
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Unified Protocol (UP), Taper and Monitoring (TAP-M)
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Overlapping Neural Circuits in Pediatric OCD

NCT02421315
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
CBT treatment for OCD based on Exposure & Response Prevention (EX/RP) and when indicated medication treatment
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
5 Years to 17 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 2 Interventional Results available

N-Acetylcysteine for Pediatric Trichotillomania

NCT00993265
View directory record Official record
Conditions
Trichotillomania, Hair Pulling
Interventions
N-Acetylcysteine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
8 Years to 17 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 7, 2026, 7:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurobiology of Sensory Phenomena in Obsessive-Compulsive Disorder

NCT03451409
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Tasked based functional MRI (fMRI), Eye Tracking Device
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 60 Years
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2024 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Increasing Treatment Efficacy Using SMART Methods for Personalizing Care

NCT04642898
View directory record Official record
Conditions
Anxiety Disorders, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
Interventions
Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 7, 2026, 7:45 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Exposure Therapy for OCD

NCT06173752
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure therapy
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Diego, California • Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 3 Interventional

Study to Determine the Efficacy and Safety of Adjunctive Topiramate in the Treatment of Obsessive-Compulsive Disorder

NCT00187928
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Topiramate
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Oct 7, 2026, 7:45 AM EDT
Active, not recruiting Not applicable Interventional

Open/Aftercare Treatment for Participants Diagnosed With Obsessive Compulsive Disorder

NCT03511534
View directory record Official record
Conditions
OCD
Interventions
Psychotherapy, Pharmacotherapy
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional

Safety and Effectiveness of Gamma Capsulotomy in Intractable OCD

NCT01849809
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Gamma Ventral Capsulotomy
Procedure
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Oct 7, 2026, 7:45 AM EDT
Active, not recruiting Not applicable Interventional

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

NCT06138782
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional

Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding

NCT02306174
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure-based Class for Compulsive Hoarding
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 1 Interventional

Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

NCT03356483
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Psilocybin (0.25mg/kg), Niacin (250mg)
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 7, 2026, 7:45 AM EDT
Not listed Not applicable Interventional

Testing a Brief Exercise Intervention in Hoarding Disorder

NCT06561659
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Exercise Condition, Relaxation Control Condition
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
45 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional

Personalized Computerized Inhibitory Control Training for OCD

NCT02378896
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Personalized Computer Program, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2018 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 2 Interventional

Testing a New Therapy for Trichotillomania

NCT00872742
View directory record Official record
Conditions
Trichotillomania
Interventions
Acceptance enhanced behavior therapy (AEBT), Psychoeducation and supportive therapy (PST)
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Phase 2 Interventional Results available

Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP)

NCT02062658
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Ketamine, Exposure and Response Prevention
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of a Neurobehavioral Intervention on Symptoms of Obsessive Compulsive Disorder

NCT01414023
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Cognitive Control Training, Peripheral Vision Task
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Oct 7, 2026, 7:45 AM EDT
Terminated Phase 2Phase 3 Interventional

Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder

NCT00299611
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Sertraline, Levetiracetam, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Oct 7, 2026, 7:45 AM EDT
Active, not recruiting Phase 1 Interventional

Effects of Repeated Psilocybin Dosing in OCD

NCT05370911
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Recruiting Not applicable Interventional

Neurophysiological Investigation of the Approach-avoidance Axis in OCD: Applications to Neuromodulation

NCT06596447
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Neuromodulation
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
22 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 7, 2026, 7:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

NCT02028247
View directory record Official record
Conditions
Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified, Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder
Interventions
Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 13 Years
Enrollment
214 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 7, 2026, 7:45 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder

NCT04806516
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 7, 2026, 7:45 AM EDT