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ClinicalTrials.gov public records Last synced Oct 6, 2026, 1:45 AM EDT

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Showing 193–216 of 362 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-Compulsive Disorder (OCD) Clear all
Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder

NCT04693351
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Troriluzole, Placebo
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
589 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
49
States / cities
Phoenix, Arizona • Culver City, California • La Jolla, California + 45 more
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Recruiting Phase 2 Interventional

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

NCT06376734
View directory record Official record
Conditions
Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Sunnyvale, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors

NCT03530800
View directory record Official record
Conditions
Trichotillomania, Skin-Picking
Interventions
Dronabinol, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 2, 2022 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Phase 2 Interventional Results available

Ketamine Infusion for Obsessive-Compulsive Disorder

NCT01349231
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children

NCT03584945
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms in Children
Interventions
Cognitive Behavioral Therapy, Community Referral as appropriate
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 14 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 6, 2026, 1:45 AM EDT
Active, not recruiting Not applicable Interventional

Imaging-Guided Low Intensity Focused Ultrasound (LIFU)

NCT05467085
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
BX Pulsar 1002
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Boston, Massachusetts • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Control and Reward Circuits in Obsessive Compulsive Disorder

NCT02221518
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure & Response Prevention (EX/RP)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"

NCT03414619
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
Interventions
Cognitive Control Tasks and Script Driven Imagery
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 6, 2026, 1:45 AM EDT
Recruiting Phase 1Phase 2 Interventional

Pilot Study of RR-HNK in OCD

NCT06575075
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
RR-HNK/Hydroxynorketamine, Placebo
Drug
Lead sponsor
Carolyn Rodriguez
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Not listed Not applicable Interventional

Testing a Brief Exercise Intervention in Hoarding Disorder

NCT06561659
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Exercise Condition, Relaxation Control Condition
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
45 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 6, 2026, 1:45 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery

NCT02320266
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation

NCT04075890
View directory record Official record
Conditions
OCD, Decision-Making, tDCS, fMRI
Interventions
transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional

Leveraging Technological Advancements to Improve the Treatment of Trichotillomania

NCT05003401
View directory record Official record
Conditions
Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling
Interventions
HabitAware Keen2
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Phase 2 Interventional Results available

N-Acetylcysteine for Pediatric Trichotillomania

NCT00993265
View directory record Official record
Conditions
Trichotillomania, Hair Pulling
Interventions
N-Acetylcysteine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
8 Years to 17 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 6, 2026, 1:45 AM EDT
Recruiting Not applicable Interventional

Interpretation Bias as a Mechanism of Treatment Response in OCD

NCT05224414
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive bias modification for interpretation bias, Psychoeducation
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Phase 2 Interventional Results available

N-Acetyl Cysteine in Trichotillomania

NCT00354770
View directory record Official record
Conditions
Trichotillomania
Interventions
Placebo, N-Acetyl Cysteine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 6, 2026, 1:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Correlates of Compulsivity

NCT05195476
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional

Assessing Models of Exposure Therapy

NCT01679457
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms
Interventions
ACT-Focused ERP, TAU-ERP
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 6, 2026, 1:45 AM EDT
Recruiting Not applicable Interventional

Anxiety Skills Study

NCT07774481
View directory record Official record
Conditions
Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders, Social Anxiety Disorder, Panic Disorder (With or Without Agoraphobia), Generalized Anxiety Disorder, Obsessive-Compulsive Disorder, Specific Phobia
Interventions
Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)

NCT03457675
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Activa PC+S DBS implant for OCD, One Month Blinded Discontinuation Period
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Terminated Phase 4 Interventional Results available

Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS

NCT04015596
View directory record Official record
Conditions
PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive Disorder
Interventions
Naproxen Sodium, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 15 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 6, 2026, 1:45 AM EDT
Not listed No phase listed Observational

Discovering Factors in the Clinical Study Journey of Patients With OCD

NCT05881356
View directory record Official record
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Power Life Sciences Inc.
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 6, 2026, 1:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electrophysiological Recording for Patients Receiving Deep Brain Stimulation Electrode for Treatment-resistant Obsessive-compulsive Disorder

NCT01429558
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 6, 2026, 1:45 AM EDT
Completed Not applicable Interventional Results available

TMS for Improving Response Inhibition in Adolescents With OCD

NCT05104697
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Bradley Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 6, 2026, 1:45 AM EDT