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ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:47 PM EDT

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Showing 1–24 of 365 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-compulsive Disorder Clear all
Terminated Not applicable Interventional

The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens

NCT02998502
View directory record Official record
Conditions
Anxiety, Panic Disorder
Interventions
Freespira Breathing System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 17 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers

NCT02355002
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Task Control Circuit Targets for Obsessive Compulsive Behaviors in Children

NCT03584945
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms in Children
Interventions
Cognitive Behavioral Therapy, Community Referral as appropriate
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 14 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Ann Arbor, Michigan • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 20, 2026, 5:47 PM EDT
Terminated Phase 2Phase 3 Interventional

Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder

NCT00299611
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Sertraline, Levetiracetam, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Contingency Management for Hoarding Disorder

NCT04894851
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Contingency Management
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 20, 2026, 5:47 PM EDT
Completed No phase listed Observational

Study of Memantine Augmentation in Severe Obsessive-Compulsive Disorder

NCT00869505
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2009 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Phase 2 Interventional Results available

Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder

NCT00215137
View directory record Official record
Conditions
OCD
Interventions
escitalopram, Placebo ( sugar pill)
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2014 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Tolcapone in Obsessive Compulsive Disorder

NCT03348930
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Tolcapone 200 MG
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Web-based Acceptance and Commitment Therapy for Hoarding Disorder

NCT04239729
View directory record Official record
Conditions
Hoarding Disorder
Interventions
ACT Website and Coaching
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 20, 2026, 5:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Links Between OCD and Anorexia

NCT02085057
View directory record Official record
Conditions
Anorexia Nervosa, Obsessive-compulsive Disorder
Interventions
Functional Magnetic Resonance Imaging
Procedure
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 19 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2017 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Rehab and Exposure Treatment for Hoarding

NCT02402647
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Treatment (CREST), Exposure Therapy (ET)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Phase 2 Interventional Results available

Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)

NCT01100255
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Ketamine infusion, Saline
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 20, 2017 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Bias Modification for Thought-Action Fusion

NCT03921255
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive Bias Modification
Other
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Oct 20, 2026, 5:47 PM EDT
Enrolling by invitation No phase listed Observational

Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models

NCT06792175
View directory record Official record
Conditions
Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD), Attention Deficit Hyperactivity Disorder (ADHD), Schizophrenia Spectrum &Amp; Other Psychotic Disorders, Post Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Solicue Machine Learning Models, Mercuria Machine Learning Models
Diagnostic Test
Lead sponsor
Psyrin Inc.
Industry
Eligibility
13 Years to 60 Years
Enrollment
500 participants
Timeline
2025 – 2026
U.S. locations
2
States / cities
Brookline, Massachusetts • Zanesville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Comparison of Treatment for Hoarding Disorder

NCT02040805
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 20, 2026, 5:47 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Sonication-based OCD Neurosurgical Intervention Via Capsulotomy

NCT06131502
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 64 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Palo Alto, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 20, 2026, 5:47 PM EDT
Recruiting Phase 2 Interventional

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

NCT05783817
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
3,4-Methyl enedioxy methamphetamine, Methamphetamine, Cognitive Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
Carolyn Rodriguez
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 20, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Stepped Care Treatment for Anxiety Resilience

NCT07228143
View directory record Official record
Conditions
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia, Obsessive Compulsive Disorder (OCD), Panic Disorder (With or Without Agoraphobia)
Interventions
Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
Behavioral
Lead sponsor
Andrew Wiese
Other
Eligibility
7 Years to 17 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Digital Health Interventions for Obsessive Compulsive Disorder (OCD)

NCT04136626
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Perspectives OCD, The Health and Well-Being Program
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Cannabinoid Medication for Adults With OCD

NCT02911324
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Nabilone, Exposure and Response Prevention Therapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Oct 20, 2026, 5:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Correlates of Compulsivity

NCT05195476
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 20, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Efficacy of COMB (Comprehensive Behavioral) Model of Treatment of Trichotillomania

NCT01878110
View directory record Official record
Conditions
Trichotillomania, Hair-Pulling Disorder
Interventions
COMB
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 20, 2026, 5:47 PM EDT
Enrolling by invitation No phase listed Observational

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

NCT06823024
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD, Generalized Anxiety Disorder (GAD)
Interventions
Not listed
Lead sponsor
Psyrin Inc.
Industry
Eligibility
18 Years to 68 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Sunnyvale, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 20, 2026, 5:47 PM EDT
Completed No phase listed Observational

Functional Magnetic Resonance Imaging (fMRI) During Deep Brain Stimulation (DBS) to Treat Parkinson's Disease

NCT01809613
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Functional Magnetic Resonance Imaging (fMRI)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 3, 2017 · Synced Oct 20, 2026, 5:47 PM EDT