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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:22 PM EDT

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Showing 337–360 of 366 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-compulsive Disorder Clear all
Completed Not applicable Interventional

Web-based Acceptance and Commitment Therapy for Hoarding Disorder

NCT04239729
View directory record Official record
Conditions
Hoarding Disorder
Interventions
ACT Website and Coaching
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder

NCT01453439
View directory record Official record
Conditions
Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder, Anxiety Disorders, Somatoform Disorders
Interventions
Cognitive Behavioral Therapy, Supportive Psychotherapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Boston, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 21, 2026, 7:22 PM EDT
Completed No phase listed Observational

Clinical Outcomes From NOCD Treatment of Obsessive-Compulsive Disorder Using Exposure and Response Prevention

NCT04701372
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and response prevention therapy
Behavioral
Lead sponsor
NOCD
Industry
Eligibility
10 Years and older
Enrollment
2,069 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Phase 2 Interventional

Stepped Care in the Treatment of Trichotillomania

NCT01118637
View directory record Official record
Conditions
Trichotillomania
Interventions
StopPulling.com
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 27, 2013 · Synced Oct 21, 2026, 7:22 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)

NCT05940324
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Ketamine, Naltrexone Pill, Placebo pill
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)

NCT03459456
View directory record Official record
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Provocation OC task (Provoc), Trier Social Stress Test (TSST), Exposure provocation task
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Not applicable Interventional Results available

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

NCT01947647
View directory record Official record
Conditions
Major Depressive Disorder, Persistent Depressive Disorder, Posttraumatic Stress Disorder, Panic Disorder, Social Phobia, Specific Phobia, Generalized Anxiety Disorder, Obsessive Compulsive Disorder
Interventions
Transdiagnostic Behavior Therapy, Behavioral Activation Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 21, 2026, 7:22 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

NCT06624137
View directory record Official record
Conditions
OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer, Migraine, PTSD, PTSD - Post Traumatic Stress Disorder, Addiction, Tobacco Use Disorder, Obsessive Compulsive Disorder (OCD), Opioid Use Disorder
Interventions
Serotonergic Psychedelic, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Hamden, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Terminated Not applicable Interventional

The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens

NCT02998502
View directory record Official record
Conditions
Anxiety, Panic Disorder
Interventions
Freespira Breathing System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 17 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Not applicable Interventional

Assessing Models of Exposure Therapy

NCT01679457
View directory record Official record
Conditions
Obsessive-compulsive Disorders and Symptoms
Interventions
ACT-Focused ERP, TAU-ERP
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 21, 2026, 7:22 PM EDT
Recruiting Not applicable Interventional

Mechanisms of Exposure Therapy for OCD

NCT06173752
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure therapy
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Diego, California • Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Not listed Not applicable Interventional

A RCT of an AEBT Website for Adults With Skin Picking

NCT05989737
View directory record Official record
Conditions
Excoriation (Skin-Picking) Disorder
Interventions
Acceptance-Enhanced Behavior Therapy
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 21, 2026, 7:22 PM EDT
Not yet recruiting Phase 2 Interventional

Aripiprazole in Body Focused Repetitive Behaviors

NCT05545891
View directory record Official record
Conditions
Trichotillomania (Hair-Pulling Disorder), Dermatillomania
Interventions
Placebo, Aripiprazole
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 21, 2026, 7:22 PM EDT
Recruiting Not applicable Interventional

Neurostimulation Versus Therapy for Problems With Emotions

NCT05712057
View directory record Official record
Conditions
Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders, OCD, Impulse Control Disorder, Eating Disorders, Emotional Dysfunction, Emotional Instability, Emotional Distress, Emotional Maladjustment, Emotional Impulsivity, Obsessive-Compulsive Disorder, Emotion Dysregulation, Borderline Personality Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring, Emotional Awareness Training
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Not applicable Interventional

Leveraging Technological Advancements to Improve the Treatment of Trichotillomania

NCT05003401
View directory record Official record
Conditions
Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling
Interventions
HabitAware Keen2
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial of Tolcapone in Obsessive Compulsive Disorder

NCT05624528
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, OCD
Interventions
Tolcapone, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Cannabinoid Medication for Adults With OCD

NCT02911324
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Nabilone, Exposure and Response Prevention Therapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Sertraline and Cognitive Behavioral Therapy in Treating Pediatric Obsessive-Compulsive Disorder

NCT00382291
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Regular Titration, Placebo, Slow Titration
Drug
Lead sponsor
University of Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
2
States / cities
Gainesville, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 21, 2026, 7:22 PM EDT
Recruiting Not applicable Interventional

Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms

NCT07217925
View directory record Official record
Conditions
Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation, Post Traumatic Stress Symptoms
Interventions
Neuroptimal (Zengar, Inc.) Neurofeedback
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Not yet recruiting No phase listed Observational

Locating Biomarkers in OCD Through Behavioral Tasks

NCT03313622
View directory record Official record
Conditions
OCD, Obsessive-Compulsive Disorder
Interventions
Beads Task, PROVOC Tasks
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder

NCT04641143
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Troriluzole, Placebo
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
73
States / cities
Chandler, Arizona • Phoenix, Arizona • Bellflower, California + 62 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Recruiting Not applicable Interventional

CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD

NCT05609916
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Obsessive-Compulsive Disorder, Obsessive-Compulsive Disorder in Children, Obsessive-Compulsive Disorder in Adolescence
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 21, 2026, 7:22 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Cost-Effectiveness of Adding Web-Based Cognitive-Behavioral Therapy (CBT) to Luvox CR for Obsessive Compulsive Disorder (OCD)

NCT00743834
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Luvox CR, Behavioral Therapy
Drug · Behavioral
Lead sponsor
Rogers Center for Research & Training, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2008 · Synced Oct 21, 2026, 7:22 PM EDT
Terminated Phase 4 Interventional Results available

Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder

NCT00592852
View directory record Official record
Conditions
Pediatric Bipolar Disorder, Pediatric OCD
Interventions
fluoxetine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 21, 2026, 7:22 PM EDT