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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:06 PM EDT

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Showing 145–168 of 365 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-compulsive Disorder Clear all
Completed Not applicable Interventional

ERP Plus Improv Group Therapy for OCD (IMPROVE Study)

NCT06265233
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Group Improv sessions, Group Exposure and Response Prevention (ERP) Therapy
Other · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 2 Interventional Results available

Antibiotic Treatment Trial for the PANDAS/PANS Phenotype

NCT01617083
View directory record Official record
Conditions
PANS, PANDAS, Obsessive Compulsive Disorder (OCD)
Interventions
Azithromycin, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
4 Years to 14 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin Administration in BDD and OCD

NCT02671266
View directory record Official record
Conditions
Body Dysmorphic Disorder, Obsessive-compulsive Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 23, 2018 · Synced Oct 20, 2026, 11:06 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Neural Mechanisms of Decision Making in Hoarding Disorder

NCT03487224
View directory record Official record
Conditions
Hoarding Disorder
Interventions
MRI with fMRI frequency
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Role of Theta Frequency Oscillations in Proactive and Reactive Control Processes in Youth With Attention Deficit Hyperactivity Disorder (ADHD) and Obsessive Compulsive Disorder (OCD)

NCT07566468
View directory record Official record
Conditions
ADHD, Obsessive Compulsive Disorder (OCD), Healthy Volunteer
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
10 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder

NCT00864123
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Cognitive-behavioral therapy, D-cycloserine, Placebo pill
Behavioral · Drug
Lead sponsor
University of South Florida
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2012 · Synced Oct 20, 2026, 11:06 PM EDT
Active, not recruiting Not applicable Interventional

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

NCT06138782
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Psilocybin for Treatment of OCD-2

NCT06992999
View directory record Official record
Conditions
Obsessive - Compulsive Disorder
Interventions
Low Dose Psilocybin, High Dose Psilocybin
Drug
Lead sponsor
Francisco A Moreno
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Recruiting Not applicable Interventional

Neurostimulation Versus Therapy for Problems With Emotions

NCT05712057
View directory record Official record
Conditions
Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders, OCD, Impulse Control Disorder, Eating Disorders, Emotional Dysfunction, Emotional Instability, Emotional Distress, Emotional Maladjustment, Emotional Impulsivity, Obsessive-Compulsive Disorder, Emotion Dysregulation, Borderline Personality Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring, Emotional Awareness Training
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Increasing Treatment Efficacy Using SMART Methods for Personalizing Care

NCT04642898
View directory record Official record
Conditions
Anxiety Disorders, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
Interventions
Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 20, 2026, 11:06 PM EDT
Completed No phase listed Observational

Genetics of Obsessive-Compulsive Disorder

NCT00001548
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurocircuit Mechanisms of OCD Across the Lifespan

NCT02437773
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive Behavioral Therapy - Adolescents, Stress Management Therapy - Adolescents, Optional CBT - Adolescents, Cognitive Behavioral Therapy - Adults, Stress Management Therapy - Adults, Optional CBT - Adults, fMRI only - Healthy Control Adults, fMRI only - Healthy Control Adolescents
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 45 Years
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2020 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Not applicable Interventional Results available

Motivational Interviewing to Enhance Behavioral Change in Older Adults With Hoarding Disorder

NCT05237466
View directory record Official record
Conditions
Hoarding Disorder
Interventions
RECLAIM: Reducing Clutter and Increasing Meaning, Sorting Practice
Behavioral
Lead sponsor
Mississippi State University
Other
Eligibility
60 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Enrolling by invitation Phase 3 Interventional

Ventral Capsulotomy for Intractable OCD

NCT05659082
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Laser Interstitial Thermal Therapy
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 20, 2026, 11:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Characterization of Childhood-Onset Obsessive-Compulsive Disorder

NCT00044239
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
4 Years to 12 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2010
U.S. locations
4
States / cities
Little Rock, Arkansas • Gainesville, Florida • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 20, 2026, 11:06 PM EDT
Recruiting Not applicable Interventional

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

NCT05160129
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Selective focal stimulation of ALIC-pathways
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Recruiting Not applicable Interventional

Cognitive Control Targets for the Treatment of Obsessive Compulsive Disorder in Young Children

NCT06102941
View directory record Official record
Conditions
Obsessive-Compulsive Disorder in Children
Interventions
Cognitive Control Training (CT)
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 2 Interventional Results available

Enhancing Attention in Adults With Compulsive Hoarding

NCT01100268
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Methylphenidate ER
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Hartford, Connecticut • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2014 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Not applicable Interventional

Attention Training for Childhood Obsessive Compulsive Disorder

NCT02114918
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Attention Modification Program, Attention Control Condition
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
8 Years to 17 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2017 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents

NCT01177969
View directory record Official record
Conditions
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Interventions
Cognitive-Behavioral Therapy, Wait-list
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
11 Years to 14 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
2
States / cities
Los Angeles, California • St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Not applicable Interventional

A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD

NCT05777161
View directory record Official record
Conditions
Anxiety Disorders, Obsessive-Compulsive Disorder
Interventions
Parent Coached Exposure Therapy - Individualized, Cognitive Behavior Therapy, Parent Coached Exposure Therapy - Group (removed from study)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Sertraline on Brain Connectivity in Adolescents With OCD

NCT02797808
View directory record Official record
Conditions
OCD
Interventions
Sertraline, No Intervention
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years to 17 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2021 · Synced Oct 20, 2026, 11:06 PM EDT
Recruiting No phase listed Observational

Developing Brain, Impulsivity and Compulsivity

NCT04631042
View directory record Official record
Conditions
Typical Development, Obsessive Compulsive Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
6 Years to 80 Years
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 11:06 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)

NCT01411774
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Cognitive-behavioral therapy, d-cycloserine, Pill placebo
Behavioral · Drug
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
St. Petersburg, Florida • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 20, 2026, 11:06 PM EDT