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Showing 1–24 of 361 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obsessive-compulsive Disorder (OCD) Clear all
Completed Not applicable Interventional

CBT for Pediatric OCD: Community Training Pilot

NCT02202915
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Behavioral Checklist
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Sep 14, 2026, 4:35 PM EDT
Active, not recruiting Not applicable Interventional

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

NCT05967468
View directory record Official record
Conditions
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Generalized Anxiety Disorder, Separation Anxiety, Panic Disorder, Panic Disorder With Agoraphobia, Panic Attacks
Interventions
Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
Behavioral · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 13 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional

Theta Burst Stimulation for Compulsive Behavior Non-invasive Brain Stimulation Study

NCT03265015
View directory record Official record
Conditions
Compulsive Behavior, Obsessive-Compulsive Disorder
Interventions
Habit Override Practice, Transcranial Magnetic Stimulation
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 15, 2022 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation

NCT04075890
View directory record Official record
Conditions
OCD, Decision-Making, tDCS, fMRI
Interventions
transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)

NCT01411774
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Cognitive-behavioral therapy, d-cycloserine, Pill placebo
Behavioral · Drug
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
2
States / cities
St. Petersburg, Florida • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 4 Interventional Results available

Effects of Ondansetron in Obsessive-compulsive and Tic Disorders

NCT03239210
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Tic Disorders, Tourette Syndrome
Interventions
Ondansetron, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 60 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 14, 2026, 4:35 PM EDT
Recruiting Not applicable Interventional

OCD LIFU Target Engagement

NCT07558148
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 14, 2026, 4:35 PM EDT
Recruiting No phase listed Observational

A Multicenter Pediatric Deep Brain Stimulation Registry

NCT06585618
View directory record Official record
Conditions
Dystonia, Epilepsy in Children, Cerebral Palsy, Tourette Syndrome, Obsessive-Compulsive Disorder, Neurologic Disorder, Movement Disorders in Children, Movement Disorders, Deep Brain Stimulation
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 14, 2026, 4:35 PM EDT
Terminated Not applicable Interventional Results available

Cognitive Behavioral Strategies and Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Open Label Study

NCT02528331
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Transcranial magnetic stimulation, Cognitive behavioral therapy
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 2 Interventional Results available

Open Label Trial of Rapastinel (Formerly GLYX-13) in Individuals With Obsessive-Compulsive Disorder

NCT02267629
View directory record Official record
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Rapastinel (formerly GLYX-13)
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional

Skin Picking Approach Avoidance Task

NCT04099537
View directory record Official record
Conditions
Skin-Picking
Interventions
Computerized cognitive training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Sep 14, 2026, 4:35 PM EDT
Active, not recruiting Not applicable Interventional

Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder

NCT03184454
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Medtronic Percept Deep Brain Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Charlestown, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism

NCT01563003
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
11 Years to 16 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 4 Interventional

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome

NCT05657860
View directory record Official record
Conditions
Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking
Interventions
Guanfacine Extended Release, Placebo
Drug · Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
6 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 14, 2026, 4:35 PM EDT
Terminated Phase 4 Interventional Results available

Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS

NCT04015596
View directory record Official record
Conditions
PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive Disorder
Interventions
Naproxen Sodium, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
6 Years to 15 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 2 Interventional Results available

N-Acetyl Cysteine in Trichotillomania

NCT00354770
View directory record Official record
Conditions
Trichotillomania
Interventions
Placebo, N-Acetyl Cysteine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 1 Interventional

Psilocybin for Treatment of Obsessive Compulsive Disorder

NCT03300947
View directory record Official record
Conditions
Obsessive-compulsive Disorder (OCD)
Interventions
Psilocybin 100 mcg/kg, Psilocybin 300 mcg/kg, Lorazepam 1 mg
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 4 Interventional

Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections

NCT00001658
View directory record Official record
Conditions
Autoimmune Disease, Mental Disorder, Obsessive Compulsive Disorder, Streptococcal Infection, Tic Disorder
Interventions
Amoxicillin
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional

Web Based Therapist Training on Cognitive Behavior Therapy for Anxiety Disorders

NCT02089984
View directory record Official record
Conditions
Anxiety Disorders, Obsessive Compulsive Disorder, PTSD
Interventions
Internet Based CBT Training
Behavioral
Lead sponsor
Center for Psychological Consultation
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 14, 2026, 4:35 PM EDT
Not listed Not applicable Interventional

Improving Access to Child Anxiety Treatment

NCT03528109
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Anxiety Disorders, Pediatric Disorder, Anxiety, OCD, Phobia, Agoraphobia, Generalized Anxiety, Generalized Anxiety Disorder, Selective Mutism, Separation Anxiety, Social Anxiety, Social Anxiety Disorder, Panic Disorder
Interventions
Exposure Therapy
Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of Virtual Reality for Providing Exposure Therapy to Children

NCT03208348
View directory record Official record
Conditions
Generalized Anxiety Disorder
Interventions
Pilot Virtual Reality
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
7 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 2 Interventional Results available

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

NCT00956085
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Memantine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Sep 14, 2026, 4:35 PM EDT
Completed No phase listed Observational

Initial Development and Dissemination of OC-Go

NCT03126305
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
OC-Go
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 17 Years
Enrollment
8 participants
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 14, 2026, 4:35 PM EDT
Completed Phase 2 Interventional Results available

Marinol in Trichotillomania or Obsessive Compulsive Disorder

NCT01093976
View directory record Official record
Conditions
Trichotillomania, Obsessive Compulsive Disorder
Interventions
Dronabinol
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 14, 2026, 4:35 PM EDT