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ClinicalTrials.gov public records Last synced Oct 15, 2026, 8:10 PM EDT

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Showing 625–648 of 915 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstetric Labor Complications Clear all
Completed Phase 2 Interventional

Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus

NCT00187447
View directory record Official record
Conditions
Patent Ductus Arteriosus
Interventions
indomethacin (two different dosing regimens)
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 48 Hours
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Davis, California • Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 4, 2008 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional

Flow-synchronized Nasal IMV in Preterm Infants

NCT02085499
View directory record Official record
Conditions
Premature Infant Disease, Respiratory Insufficiency
Interventions
non-synchronized NIMV, Synchronized NIMV
Other
Lead sponsor
University of Miami
Other
Eligibility
Not listed
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional Results available

Prevention of Preterm Birth With a Pessary in Singleton Gestations

NCT02056652
View directory record Official record
Conditions
Preterm Birth, Short Cervix
Interventions
Bioteque cup pessary
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
4
States / cities
Danville, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional

Study to Determine if Gloving in Addition to Hand Hygiene Will Prevent Invasive Infections and Necrotizing Enterocolitis

NCT01729000
View directory record Official record
Conditions
Neonatal Infection, Neonatal Necrotizing Enterocolitis
Interventions
Gloves
Other
Lead sponsor
University of Virginia
Other
Eligibility
Up to 8 Days
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2012 · Synced Oct 15, 2026, 8:10 PM EDT
Not yet recruiting Not applicable Interventional

Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates

NCT07060911
View directory record Official record
Conditions
RDS of Prematurity, Preterm Birth, Lung Diseases
Interventions
Lung monitoring with the Neola device
Device
Lead sponsor
Neola Medical Inc
Industry
Eligibility
1 Day to 44 Weeks
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Palo Alto, California • Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)

NCT00099164
View directory record Official record
Conditions
Preterm Birth, Pregnancy, Multifetal
Interventions
17 alpha-hydroxyprogesterone caproate (17P)
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
795 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
14
States / cities
Birmingham, Alabama • Chicago, Illinois • Detroit, Michigan + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Assessment of DHA On Reducing Early Preterm Birth

NCT02626299
View directory record Official record
Conditions
Preterm Birth
Interventions
Docosahexaenoic acid - 800mg/day, Docosahexaenoic acid - 200mg/day, Placebo
Drug · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
3
States / cities
Kansas City, Kansas • Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2021 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 1Phase 2 Interventional

Effects of Massage on the Immune System of Preterm Infants

NCT00317278
View directory record Official record
Conditions
Premature Birth, Stress
Interventions
massage therapy, Sham
Other
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
28 Weeks to 33 Weeks
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2009 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)

NCT00724594
View directory record Official record
Conditions
Chorioamnionitis, Brain Injury
Interventions
N-acetylcysteine, Control
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling

NCT04859114
View directory record Official record
Conditions
Premature Birth
Interventions
Format of outcome data presentation, Displayed chance of survival
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,052 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional Results available

Evaluation of CRB in PROM Patients

NCT01736852
View directory record Official record
Conditions
Premature Rupture of Fetal Membranes
Interventions
CRB, Pitocin
Device · Drug
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older · Female only
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
4
States / cities
Tucson, Arizona • Tampa, Florida • Louisville, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 15, 2026, 8:10 PM EDT
Not listed No phase listed Observational

Study of Bedside EEG to Evaluate Brain Injury in Premature Newborns

NCT00516334
View directory record Official record
Conditions
Brain Injury, Seizures, Cerebral Palsy
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
1 Day to 36 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2012 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meditation for NICU Moms

NCT03574766
View directory record Official record
Conditions
Breast Feeding, Premature Birth, Stress, Depression, Postpartum, Anxiety, Self Efficacy, Behavior, Maternal, Insufficient Lactation
Interventions
Meditation
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond Heights, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

NCT02509312
View directory record Official record
Conditions
Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity, Coagulation Defect; Postpartum, Postoperative Pain, Ketorolac Adverse Reaction, Blood Loss, Postoperative
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional

Randomized Controlled Trial of Higher-Volume Feedings in Preterm Neonates

NCT02377050
View directory record Official record
Conditions
Infant Premature
Interventions
Higher Volume Feeding Goal
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 1 Month
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional

Effects of Massage Therapy and Kinesthetic Stimulation on Pre-Term Infants

NCT00661791
View directory record Official record
Conditions
Prematurity
Interventions
Massage therapy without exercise, Massage therapy with exercise
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
28 Weeks to 32 Weeks
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2008 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19

NCT04718220
View directory record Official record
Conditions
Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus, Neonatal Infection, Prenatal Stress, Preterm Birth
Interventions
Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Female only
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 2Phase 3 Interventional

Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

NCT03231735
View directory record Official record
Conditions
Ventilator-Induced Lung Injury, Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, Preterm Infant
Interventions
Mid frequency ventilation, Standard frequency ventilation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 3 Days
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
2
States / cities
Birmingham, Alabama • Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 15, 2026, 8:10 PM EDT
Recruiting Phase 2 Interventional

Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project

NCT06004674
View directory record Official record
Conditions
Adverse Pregnancy Outcome
Interventions
Lovenox 40mg
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 15, 2026, 8:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Coagulation Factor Changes Associated With Postpartum Hysterectomies

NCT00456547
View directory record Official record
Conditions
Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Not applicable Interventional

Randomized Study of Human-Milk Based Nutrition Versus Formula in Premature Infants

NCT00506584
View directory record Official record
Conditions
Infant, Very Low Birth Weight
Interventions
Pasteurized human milk and pasteurized human milk fortifier, Human milk fortifier (bovine-based), pre-term formula, Pre-term/term formula
Dietary Supplement
Lead sponsor
Prolacta Bioscience
Industry
Eligibility
1 Day to 21 Days
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
12
States / cities
Berkeley, California • San Diego, California • New Haven, Connecticut + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2010 · Synced Oct 15, 2026, 8:10 PM EDT
Terminated Phase 1 Interventional

Timolol for the Prevention of Proliferation of Infantile Hemangioma (TiPPIH Trial)

NCT01434849
View directory record Official record
Conditions
Infantile Hemangioma, Very Low Birth Weight Infants
Interventions
topical 0.5% Timolol maleate, Control (placebo) group
Drug
Lead sponsor
Alice K. Gong
Other
Eligibility
Up to 6 Months
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2016 · Synced Oct 15, 2026, 8:10 PM EDT
Completed No phase listed Observational

Pulse Oximetry Measurement and Transfusions

NCT04249193
View directory record Official record
Conditions
Hypoxia Neonatal, Premature, Blood Transfusion
Interventions
Transfusion
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
Up to 6 Weeks
Enrollment
75 participants
Timeline
2014 – 2017
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 15, 2026, 8:10 PM EDT
Completed Phase 1 Interventional Results available

Enteral L Citrulline Supplementation in Preterm Infants - Safety, Efficacy and Dosing

NCT03649932
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Bronchopulmonary Dysplasia Associated Pulmonary Hypertension, Pulmonary Hypertension, Premature Birth, Chronic Lung Disease of Prematurity
Interventions
Enteral L-citrulline
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 30 Weeks
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Oct 15, 2026, 8:10 PM EDT