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ClinicalTrials.gov public records Last synced Oct 16, 2026, 12:24 PM EDT

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Showing 721–744 of 4,090 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Clear all
Completed Phase 1Phase 2 Interventional Results available

Pharmacological Activation of HMN for OSA

NCT03640052
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral capsule, LTM1201L, LTM1201LN, LTM1201LB, LTM1201LD
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 2 Interventional

Study Assessing Utility of a Clinical Questionnaire to Identify Subjects With Features of Both Asthma and Chronic Obstructive Pulmonary Disease (COPD)

NCT02302417
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Spirometry, ACOS clinical questionnaire
Procedure · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
1,215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
12
States / cities
Newport Beach, California • Upland, California • Sunset, Louisiana + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2017 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional Results available

Vivatmo Pro™ for Fractional Exhaled Nitric Oxide (FeNO) Monitoring in U.S. Asthmatic Patients

NCT04450108
View directory record Official record
Conditions
Asthma, Asthma in Children
Interventions
Vivatmo pro FeNO Test
Diagnostic Test
Lead sponsor
Bosch Healthcare Solutions GmbH
Industry
Eligibility
7 Years to 80 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
6
States / cities
Birmingham, Alabama • Bakersfield, California • White Marsh, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 16, 2026, 12:24 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma

NCT06270576
View directory record Official record
Conditions
Asthma; Eosinophilic, Asthma
Interventions
Lipopolysaccharides
Drug
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 3 Interventional

Integrated Care Program for Chronic Obstructive Pulmonary Disease

NCT01045213
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Integrated Care
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 16, 2026, 12:24 PM EDT
Recruiting Phase 3 Interventional

A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

NCT07645248
View directory record Official record
Conditions
Asthma
Interventions
HFA-152a, HFA-134a
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
12
States / cities
Aventura, Florida • Miami, Florida • Naples, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 16, 2026, 12:24 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

A Prospective, Cohort Study of Hyperpolarized 3He MRI in Chronic Obstructive Pulmonary Disease

NCT02734368
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Hyperpolarized Helium-3
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 70 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 1 Interventional

Comparative Effects of Fish Oil Supplementation and a Montelukast on EIB and Airway Inflammation in Asthma

NCT00676468
View directory record Official record
Conditions
Asthma
Interventions
Active Montelukast + Fish Oil Placebo, Active Fish Oil + Montelukast Placebo, Active Montelukast + Active Fish Oil
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 9, 2009 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 2 Interventional

PT005 MDI Dose Ranging Versus Foradil Aerolizer Study

NCT01349868
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
PT005 MDI, Formoterol Fumarate 12 μg (Foradil® Aerolizer®), Formoterol Fumarate 24 μg (Foradil® Aerolizer®), Placebo MDI
Drug · Other
Lead sponsor
Pearl Therapeutics, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
3
States / cities
Clearwater, Florida • Tampa, Florida • Spartanburg, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2012 · Synced Oct 16, 2026, 12:24 PM EDT
Terminated Phase 2 Interventional

Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA

NCT05667662
View directory record Official record
Conditions
ABPA
Interventions
Itraconazole Powder, Placebo
Drug
Lead sponsor
Pulmatrix Inc.
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
8
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Santa Monica, California + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 2 Interventional

A Safety and Tolerability Study of Levalbuterol HFA Metered Dose Inhaler in Subjects With Asthma

NCT00684827
View directory record Official record
Conditions
Asthma
Interventions
Levalbuterol HFA MDI followed by Racemic albuterol HFA MDI, Racemic Albuterol followed by levalbuterol HFA MDI
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
12 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
4
States / cities
Encinitas, California • Los Angeles, California • North Dartmouth, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Oct 16, 2026, 12:24 PM EDT
Not listed Not applicable Interventional

The Effect of Exercise on Systemic Inflammation in Veterans With COPD and OSA

NCT03431103
View directory record Official record
Conditions
COPD, OSA, Home Exercise, Inflammation
Interventions
Exercise
Behavioral
Lead sponsor
Salem Veterans Affairs Medical Center
Federal
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salem, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional Results available

Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.

NCT05139303
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Orthoapnea NOA®
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 79 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 3 Interventional Results available

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma

NCT04305405
View directory record Official record
Conditions
Severe Uncontrolled Asthma
Interventions
Benralizumab
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
6 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
7
States / cities
Los Angeles, California • Orlando, Florida • Lincoln, Nebraska + 4 more
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 16, 2026, 12:24 PM EDT
Completed No phase listed Observational

CLAD Phenotype Specific Risk Factors and Mechanisms

NCT02631720
View directory record Official record
Conditions
Lung Transplant, Post Lung Transplantation
Interventions
Blood Draw, Bronchoscopy
Procedure
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
884 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
4
States / cities
Los Angeles, California • Baltimore, Maryland • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Genotype Stratified Pharmacokinetic Study of Montelukast

NCT01086527
View directory record Official record
Conditions
Asthma
Interventions
10 mg tablet of montelukast (Singulair)
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
7 Years to 35 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional

The Breathe Well Program for Adults With Asthma

NCT02761837
View directory record Official record
Conditions
Asthma
Interventions
IVR call/text, Email
Behavioral
Lead sponsor
National Jewish Health
Other
Eligibility
19 Years to 99 Years
Enrollment
14,978 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional

The Community United to Challenge Asthma

NCT01061424
View directory record Official record
Conditions
Asthma
Interventions
community health worker, mailed information
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
5 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional

Effect of Supplemental Oral Curcumin in Patients With Atopic Asthma

NCT01179256
View directory record Official record
Conditions
Atopic Asthma
Interventions
CURCUMIN, no intervention other than stopping study
Dietary Supplement · Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 11, 2010 · Synced Oct 16, 2026, 12:24 PM EDT
Not yet recruiting Not applicable Interventional

Clearance in Primary Ciliary Dyskinesia

NCT07699302
View directory record Official record
Conditions
Primary Ciliary Dyskinesia, PCD
Interventions
Exercise, HS pretreatment with Exercise
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 16, 2026, 12:24 PM EDT
Completed No phase listed Observational

Asthma and Osteopathic Manipulative Treatment

NCT03864354
View directory record Official record
Conditions
Asthma
Interventions
Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Des Moines University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 16, 2026, 12:24 PM EDT
Completed Not applicable Interventional Results available

Evaluating Long Acting Beta Agonists Used to Treat Asthma Among Those With Either Arg/Arg or Gly/Gly Genotypes

NCT00521222
View directory record Official record
Conditions
Asthma
Interventions
Fluticasone with salmeterol, Fluticasone HFA, Ipratropium HFA, Albuterol HFA
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
3
States / cities
Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2023 · Synced Oct 16, 2026, 12:24 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis

NCT02416102
View directory record Official record
Conditions
COPD, Chronic Bronchitis
Interventions
Losartan 50 mg, Losartan 100 mg
Drug
Lead sponsor
University of Miami
Other
Eligibility
35 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 16, 2026, 12:24 PM EDT
Completed No phase listed Observational

Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

NCT00281242
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Interventions
blood draw
Other
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 29, 2016 · Synced Oct 16, 2026, 12:24 PM EDT