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ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:22 AM EDT

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Showing 1441–1464 of 4,090 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Clear all
Completed Phase 2 Interventional

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

NCT03189173
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment
Device · Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 79 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 4 Interventional Results available

Peak Inspiratory Flow and Dry Powder Inhaler Performance in COPD

NCT04606394
View directory record Official record
Conditions
COPD
Interventions
Trelegy Ellipta 100/62.5/25Mcg Inh 30D, Ventolin 90Mcg/Actuation Inhalation Aerosol
Drug
Lead sponsor
Pulmonary Research Institute of Southeast Michigan
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice

NCT01979588
View directory record Official record
Conditions
Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
Interventions
What's Going Around tool, Control
Other
Lead sponsor
Endeavor Health
Other
Eligibility
Not listed
Enrollment
206,703 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 17, 2026, 11:22 AM EDT
Not listed No phase listed Observational

Perry Virtual - A Prospective and Observational Rural Health Trial

NCT04483154
View directory record Official record
Conditions
COPD, Arrhythmia, Murmur, Heart, Chronic Disease
Interventions
Coala Heart Monitor
Device
Lead sponsor
Coala Life, Inc
Industry
Eligibility
65 Years and older
Enrollment
100 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Linden, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 24, 2020 · Synced Oct 17, 2026, 11:22 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

NCT02669251
View directory record Official record
Conditions
Chronic Graft vs Host Disease, Chronic Graft-Versus-Host Disease, Bronchiolitis Obliterans Syndrome
Interventions
MPH966
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 17, 2026, 11:22 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Analytical Validation of the abioSCOPE Device With an IgE Test Panel: Point-of-Care Precision, Sample Type Comparison and Method Correlation

NCT04401631
View directory record Official record
Conditions
Allergy, Allergic Asthma, Allergy to Cats, Allergy to House Dust, Allergy to Dog Dander (Finding), Allergy Mold, Allergy Cockroach
Interventions
Blood Collection
Device
Lead sponsor
Abionic SA
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Not applicable Interventional Results available

Vitamin D Oral Replacement in Asthma

NCT03686150
View directory record Official record
Conditions
Asthma, Vitamin D Deficiency, Pediatric Obesity
Interventions
Vitamin D3 oral regimen
Dietary Supplement
Lead sponsor
IDeA States Pediatric Clinical Trials Network
Network
Eligibility
6 Years to 17 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
15
States / cities
Little Rock, Arkansas • Wilmington, Delaware • Honolulu, Hawaii + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Oct 17, 2026, 11:22 AM EDT
Recruiting Phase 4 Interventional

Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

NCT07135427
View directory record Official record
Conditions
Alpha 1-Antitrypsin, COPD, Antibody Deficiency
Interventions
20-valent pneumococcal conjugate vaccine
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 17, 2026, 11:22 AM EDT
Not yet recruiting Not applicable Interventional

Modulating Locomotor-Respiratory Coupling Through Adaptive Exoskeleton Assistance in Patients With COPD

NCT07703527
View directory record Official record
Conditions
COPD (Chronic Obstructive Pulmonary Disease)
Interventions
Hip Exoskeleton-Assisted Walking
Device
Lead sponsor
University of Nebraska
Other
Eligibility
45 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease

NCT03819517
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Resveratrol, Placebo
Drug · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Comparison of Physical Activity Regimens as Treatments for Obstructive Sleep Apnea

NCT00956423
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
moderate-intensity aerobic and resistance training, low-intensity stretching
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2011 · Synced Oct 17, 2026, 11:22 AM EDT
Withdrawn No phase listed Observational

Mechanisms of Response to Diesel Exhaust in Subjects With Asthma

NCT01799746
View directory record Official record
Conditions
Asthma
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadephia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 4 Interventional Results available

Phase4/Symbicort® Versus Pulmicort Flexhaler® in African Americans

NCT00702325
View directory record Official record
Conditions
Asthma
Interventions
Budesonide / formoterol fumarate (SYMBICORT), Budesonide
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
12 Years and older
Enrollment
311 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
57
States / cities
Pell City, Alabama • Bentonville, Arkansas • Hot Springs, Arkansas + 54 more
Source: ClinicalTrials.gov public record
Updated Nov 9, 2012 · Synced Oct 17, 2026, 11:22 AM EDT
Recruiting Phase 2 Interventional

Down Syndrome Obstructive Sleep Apnea

NCT06043440
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Oxygen
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Los Angeles, California • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Office-Based Asthma Screening Intervention

NCT00156468
View directory record Official record
Conditions
Asthma
Interventions
Provider Prompt
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
2 Years to 12 Years
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2011 · Synced Oct 17, 2026, 11:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Microvascular and Fibrosis Imaging Study

NCT01758250
View directory record Official record
Conditions
Autoimmune Diseases, Sickle Cell Disease, Chronic Graft Versus Host Disease
Interventions
Acoustic Radiation Force Impulse (ARFI), Laser Doppler Flowmetry (LDF), Laser Doppler Perfusion Imaging (LDI), Optical Coherence Tomography (OCT), Orthogonal Polarization Spectral Imaging (OPSI), Nail fold video capillaroscopy (NVC)
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 11, 2020 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 2 Interventional Results available

Combination of Orally Inhaled BI1744CL/Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease ( COPD)

NCT00696020
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
BI 1744 CL/tiotropium bromide fixed dose combination, tiotropium bromide, Respimat® Inhaler
Drug · Device
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
22
States / cities
Riverside, California • San Diego, California • Wheat Ridge, Colorado + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2015 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 2 Interventional Results available

A Study to Assess the Effect of CK-2127107 on Physical Function in Subjects With Chronic Obstructive Pulmonary Disease

NCT02662582
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Reldesemtiv, Placebo
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Torrance, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 17, 2026, 11:22 AM EDT
Completed No phase listed Observational

Examining the Link Between Obesity, Inflammation, and Response to Asthma Medications

NCT00557180
View directory record Official record
Conditions
Asthma, Obesity
Interventions
Beclomethasone dipropionate HFA, Tiotropium bromide, Salmeterol xinafoate
Drug
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
10
States / cities
San Diego, California • San Francisco, California • Denver, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Not applicable Interventional

Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma

NCT01504646
View directory record Official record
Conditions
Asthma, Exercise-Induced Bronchoconstriction
Interventions
Lyprinol, Placebo (Olive Oil)
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Oct 17, 2026, 11:22 AM EDT
Completed Phase 4 Interventional Results available

A 24-Week Study to Evaluate the Safety and Efficacy of ADVAIR DISKUS® Inhaler 250/50mcg Plus SPIRIVA HANDIHALER® Inhaler Versus SPIRIVA HANDIHALER® Inhaler Plus Placebo DISKUS® Inhaler in Subjects With Chronic Obstructive Pulmonary Disease (COPD).

NCT00784550
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Tiotropium Bromide, Fluticasone Propionate/Salmeterol
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
40 Years to 99 Years
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
35
States / cities
Riverside, California • Fort Collins, Colorado • Clearwater, Florida + 31 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Oct 17, 2026, 11:22 AM EDT
Active, not recruiting Not applicable Interventional

Primary Care Implementation and Evaluation of Coach McLungs

NCT05059210
View directory record Official record
Conditions
Asthma
Interventions
Coach McLungs Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
5 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 17, 2026, 11:22 AM EDT
Completed No phase listed Observational

Determine the Prevalence and Severity of Asthma in HIV (Human Immunodeficiency Virus) Infected Patients

NCT02405026
View directory record Official record
Conditions
Asthma, HIV
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2017 · Synced Oct 17, 2026, 11:22 AM EDT
Completed No phase listed Observational

Exhaled Nitric Oxide and Airway Caliber in Children With Asthma

NCT01645397
View directory record Official record
Conditions
Asthma in Children
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
6 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 16, 2014 · Synced Oct 17, 2026, 11:22 AM EDT