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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:27 AM EDT

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Showing 121–144 of 824 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Apnea Clear all
Completed Not applicable Interventional

Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea

NCT05881512
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA
Interventions
Transcutaneous Upper Airway Stimulation Device
Device
Lead sponsor
Somnial Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 27, 2026, 1:27 AM EDT
Withdrawn Phase 4 Interventional

Study to Evaluate Recovery From Postoperative Pain After Sleep Apnea Surgery

NCT00380458
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Coblation (radiofrequency-based device)
Device
Lead sponsor
ArthroCare Corporation
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Comparison Study of the ICON™ CPAP Series With and Without SensAwake™

NCT01831258
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
SensAwake On, SensAwake Off
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Glendale, Arizona • Macon, Georgia • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 27, 2026, 1:27 AM EDT
Withdrawn No phase listed Observational

Sexual Dysfunction And Hypotestosteronemia In Patients With Obstructive Sleep Apnea Syndrome

NCT00832065
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Apnea, Hypotestosteronism
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 70 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
2
States / cities
Burlington, Massachusetts • Peabody, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Phase 2Phase 3 Interventional

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA

NCT06146101
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
IHL-42X Low Dose, IHL-42X High Dose, Placebo, IHL-42X (Optimal Dose), Dronabinol, Acetazolamide
Drug
Lead sponsor
Incannex Healthcare Ltd
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
20
States / cities
Chula Vista, California • Long Beach, California • Upland, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Recruiting Phase 1Phase 2 Interventional

Rescue Pharmacotherapy for OSA

NCT05293600
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo, Acetazolamide, Trazodone, Atomoxetine and eszopiclone
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional

Workflow Validation of an In-home Auto-titrating Mandibular Positioner

NCT02933112
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Auto-titrating mandibular positioner test
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 27, 2026, 1:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea

NCT00936481
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 25, 2013 · Synced Oct 27, 2026, 1:27 AM EDT
Withdrawn No phase listed Observational

Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea

NCT03155828
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Anovulation, Polycystic Ovarian Syndrome
Interventions
CPAP
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 35 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

NCT00880165
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure apparatus
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2014 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety Monitoring for a Novel 3D Printed Mandibular Advancement Device

NCT05018234
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Noval Oral Appliance
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Oct 27, 2026, 1:27 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Validity of the PAP Problems Triage Tool in Patients With PAP Treatment for Obstructive Sleep Apnea

NCT05530967
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
TT, VE
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Completed No phase listed Observational

Improving the Efficiency of the Digital Sleep Workflow Using MATRx Plus

NCT03579225
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
MATRx plus test
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers

NCT00591591
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
OxiplexTS
Device
Lead sponsor
ISS, Inc.
Industry
Eligibility
21 Years to 55 Years
Enrollment
309 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
4
States / cities
Orange, California • Stanford, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2011 · Synced Oct 27, 2026, 1:27 AM EDT
Active, not recruiting Not applicable Interventional

Dual-sided Hypoglossal neRvE stimulAtion for the treatMent of Obstructive Sleep Apnea (DREAM)

NCT03868618
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Genio™ system
Device
Lead sponsor
Nyxoah S.A.
Industry
Eligibility
22 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
16
States / cities
Birmingham, Alabama • Boca Raton, Florida • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Steroids, Sleep, and Metabolic Dysfunction in Women

NCT00805207
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS), Obstructive Sleep Apnea, Obesity
Interventions
Progesterone, testosterone, glucocorticoid, continuous positive airway pressure, Estrogen, Control
Drug · Device · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Phase 2 Interventional Results available

Crossover Trial of AD036 in Obstructive Sleep Apnea

NCT04445688
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
AD036, Atomoxetine, Placebo
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
5
States / cities
Little Rock, Arkansas • Santa Ana, California • Chevy Chase, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 27, 2026, 1:27 AM EDT
Recruiting Not applicable Interventional

Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

NCT07220525
View directory record Official record
Conditions
Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction
Interventions
HGNS Use Randomized Instructions
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Brain Sleep Deprivation MRI Effects (BEDTIME)

NCT02741505
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Actigraph
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment

NCT01939938
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Nasal and Oronasal PAP Mask
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

Validation of Safety and Efficacy for Night Shift Therapy

NCT02032706
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Deliver therapy when the supine position is detected
Device
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Murrieta, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2016 · Synced Oct 27, 2026, 1:27 AM EDT
Completed Not applicable Interventional Results available

The Evaluation of a Mask for the Treatment of Obstructive Sleep Apnea

NCT03142438
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
F&P Seal Improvement Project
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 27, 2026, 1:27 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

NCT05052216
View directory record Official record
Conditions
Pediatric Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
3 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 27, 2026, 1:27 AM EDT
Withdrawn No phase listed Observational

Can Postoperative Outcomes be Predicted From Asking OSA Screening Questions Pre-operatively?

NCT02930538
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Survey
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
3 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 27, 2026, 1:27 AM EDT