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ClinicalTrials.gov public records Last synced Oct 27, 2026, 3:19 AM EDT

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Showing 169–192 of 824 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Apnea Clear all
Completed Not applicable Interventional Results available

Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography

NCT01175031
View directory record Official record
Conditions
Sleep Apnea Central, Cheyne-Stokes Respiration, Obstructive Sleep Apnea
Interventions
Manipulation of Positive Airway Pressure (PAP)
Other
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
3
States / cities
Denver, Colorado • Gainesville, Florida • Portage, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2018 · Synced Oct 27, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional Results available

Telecommunications System in Sleep Apnea

NCT00232544
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Telecommunications system, TLC-Control
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 2Phase 3 Interventional

The ATLAST Long-Term Study

NCT01476917
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Attune Sleep Apnea System
Device
Lead sponsor
ApniCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
6
States / cities
Phoenix, Arizona • Burlingame, California • Menlo Park, California + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 27, 2026, 3:19 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients

NCT03647462
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
Continuous Positive Airway Pressure
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Enrolling by invitation Not applicable Interventional

Automated Manual Lymphatic Drainage Therapy to Improve Glymphatic Function in OSA Patients

NCT07301762
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), OSA, Obstructive Sleep Apnea
Interventions
Automated manual lymphatic drainage therapy (AMLDT) device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

NCT05988385
View directory record Official record
Conditions
Obstructive Sleep Apnea, Cognitive Decline
Interventions
Positive airway pressure, Oral appliance therapy, Positional therapy
Device
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
55 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
4
States / cities
Tucson, Arizona • New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00107848
View directory record Official record
Conditions
Narcolepsy, Sleep Apnea, Obstructive
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
55
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 2 Interventional Results available

Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

NCT03148899
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Oxytocin Intranasal Spray, Placebo Intranasal Spray
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional

Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea

NCT00205543
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
uvulopalatopharyngoplasty with or without sutures
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2012 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional

Targeted Hypoglossal Neurostimulation Study #2

NCT01796925
View directory record Official record
Conditions
Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Respiration Disorders, Signs and Symptoms, Respiratory, Syndrome, Obstructive Sleep Apnea
Interventions
aura6000 THN System
Device
Lead sponsor
ImThera Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
San Diego, California • Denver, Colorado • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 27, 2026, 3:19 AM EDT
Completed No phase listed Observational

CAP Pilot Study for Obstructive Sleep Apnea (OSA)

NCT02309749
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CAP
Other
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
21 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
St Louis, Missouri • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 27, 2026, 3:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Obstructive Sleep Apnea in Pregnancy

NCT02383706
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Obesity, Morbid
Interventions
ApneaLink Air, Berlin Quesionnaire, Epworth Sleepiness Scale, STOP-BANG questionnaire, Physical exam
Device · Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Oct 27, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional

Combination Tonsillectomy and Hypoglossal Nerve Stimulation for OSA Patients With Lateral Pharyngeal Collapse

NCT07724938
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Disordered Breathing
Interventions
Tonsillectomy, HGNS
Procedure · Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pharmacological Activation of HMN for OSA

NCT03640052
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral capsule, LTM1201L, LTM1201LN, LTM1201LB, LTM1201LD
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 27, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional

Long-term Evaluation of a Nasopharyngeal Airway

NCT07191314
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 27, 2026, 3:19 AM EDT
Active, not recruiting No phase listed Observational

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

NCT02917876
View directory record Official record
Conditions
Obstructive Sleep Apnea, Pregnancy, Obesity, Sleep
Interventions
Not listed
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 2 Interventional Results available

Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea

NCT02387710
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Tiagabine, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional Results available

Improving the Frequency and Quality of Sleep Apnea Care Management

NCT01916655
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Self-Management Care, Self-Management Mobile Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea

NCT00859950
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypoxemia
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Phase 2 Interventional

Steroids and Pain Control After Tonsillectomy

NCT03995628
View directory record Official record
Conditions
Tonsillitis, Obstructive Sleep Apnea of Child
Interventions
Dexamethasone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Years to 12 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Oct 27, 2026, 3:19 AM EDT
Recruiting Not applicable Interventional

Community Health Advocates for Motivating PAP Use in Our Neighborhoods.

NCT06047353
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Motivational Enhancement Therapy, Positive Airway Pressure (PAP) therapy
Behavioral · Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Early Phase 1 Interventional

Endothelial Function in Obstructive Sleep Apnea

NCT03122639
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Atorvastatin 10mg, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 27, 2026, 3:19 AM EDT
Completed Not applicable Interventional

Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

NCT02485236
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Low flow oxygen via nasal cannula, Humidified Nasal High Flow Therapy
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Oct 27, 2026, 3:19 AM EDT