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ClinicalTrials.gov public records Last synced Oct 14, 2026, 3:31 PM EDT

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Showing 481–504 of 761 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea/Hypopnea Syndrome Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Analysis of the Prevalence and Characteristics of Concomitant Sleep and Headache Disorders, and the Efficacy of CPAP Treatment for Headache Among Those Patients Diagnosed With Obstructive Sleep Apnea

NCT00520156
View directory record Official record
Conditions
Headache Disorder, Sleep Disorder, Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years to 80 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 23, 2007 · Synced Oct 14, 2026, 3:31 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea

NCT02721251
View directory record Official record
Conditions
Obstructive Sleep Apnea, Overweight
Interventions
Exercise, Weight Loss, Exercise + Weight Loss
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Comparison of Physical Activity Regimens as Treatments for Obstructive Sleep Apnea

NCT00956423
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
moderate-intensity aerobic and resistance training, low-intensity stretching
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2011 · Synced Oct 14, 2026, 3:31 PM EDT
Completed No phase listed Observational Results available

Effect of Opioids on Ventilation in Children With Obstructive Sleep Apnea

NCT03938259
View directory record Official record
Conditions
Respiratory Depression, Obstructive Sleep Apnea
Interventions
Fentanyl
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
2 Years to 8 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2024 · Synced Oct 14, 2026, 3:31 PM EDT
Withdrawn Not applicable Interventional

Home Study of Subjects Who Have Completed a Previous Continuous Negative External Pressure (cNEP) Clinical Trial

NCT03108417
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
continuous negative external pressure
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
22 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2017 · Synced Oct 14, 2026, 3:31 PM EDT
Withdrawn Not applicable Interventional

Positioning of Surgical Patients With Sleep Apnea

NCT02123238
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
bed positioning
Other
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 15, 2015 · Synced Oct 14, 2026, 3:31 PM EDT
Terminated Not applicable Interventional Results available

The Efficacy of a New Mathematical Formula to Predict Continuous Positive Air Pressure With an Oronasal Mask Interface.

NCT02816255
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Full Face Mask with same CPAP Pressure, Full Face Mask with new Pressure
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional

Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea

NCT00205543
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
uvulopalatopharyngoplasty with or without sutures
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2012 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Acclimate Feature for Positive Airway Pressure (PAP) Therapy

NCT01421654
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
S9 Elite with Acclimate, S9 Elite
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 14, 2026, 3:31 PM EDT
Not listed Phase 1Phase 2 Interventional

Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy

NCT05550246
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Atomoxetine, Oxybutynin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults

NCT00745251
View directory record Official record
Conditions
Sleep Apnea
Interventions
VI-0521, placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 14, 2026, 3:31 PM EDT
Completed No phase listed Observational

Correlation Between CPAP Compliance and Food Intake Timing

NCT01851811
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 14, 2026, 3:31 PM EDT
Terminated Not applicable Interventional

Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF

NCT05359965
View directory record Official record
Conditions
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Gastro Esophageal Reflux
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional Results available

Trial on Oral Appliance Design for Improving Upper Airway Function and Sleep Quality

NCT03219034
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
oral appliance - A ; washout; oral appliance B, oral appliance - B; washout; oral appliance A
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 14, 2026, 3:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Incidence of Obstructive Sleep Apnea in Pregnancy

NCT00462306
View directory record Official record
Conditions
Obstructive Sleep Apnea, Pregnancy
Interventions
Survey: Berlin questionnaire
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4,577 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 14, 2026, 3:31 PM EDT
Withdrawn No phase listed Observational

Post Discharge Circadian Rhythms Post Adenotonsillectomy

NCT03217708
View directory record Official record
Conditions
Circadian Dysrhythmia
Interventions
Jawbone UP4
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
5 Years to 10 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional Results available

Hypoglossal Nerve Stimulation on Cardiovascular Outcomes

NCT03359096
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Therapeutic HGNS, Subtherapeutic 'Sham' HGNS
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
22 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Phase 2 Interventional

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

NCT03189173
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment
Device · Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 79 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 14, 2026, 3:31 PM EDT
Recruiting No phase listed Observational

SUNOSI® (Solriamfetol) Pregnancy Registry

NCT06413420
View directory record Official record
Conditions
Narcolepsy, Obstructive Sleep Apnea, Pregnant Women and Their Offspring
Interventions
Sunosi (solriamfetol), Other prescription wake-promoting medications or stimulants, No treatment
Drug · Other
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
Female only
Enrollment
1,731 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
2
States / cities
Morrisville, North Carolina • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional

Inspiratory Muscle Strength Training for Sleep-related Breathing Disorders

NCT02709941
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Inspiratory muscle strength training, Placebo
Other
Lead sponsor
University of Arizona
Other
Eligibility
30 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Not applicable Interventional

Sleep Apnea Video Education for CPAP (SAVE-CPAP)

NCT02553694
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Enhanced education, Usual education, Usual follow up, Enhanced follow up
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 14, 2026, 3:31 PM EDT
Completed No phase listed Interventional Results available

The Evaluation of a Full Face Mask Seal for the Treatment of Obstructive Sleep Apnea

NCT03230877
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Toffee full face mask with 'Improved Seal', Toffee full face mask with 'Normal Seal'
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Oct 14, 2026, 3:31 PM EDT
Completed Phase 1 Interventional

Evaluate Sunosi® PK in Breast Milk and Plasma of Healthy Postpartum Women Following Single Dose Oral Administration

NCT05008341
View directory record Official record
Conditions
Narcolepsy, Obstructive Sleep Apnea, Excessive Daytime Somnolence, Excessive Sleepiness, Postpartum
Interventions
Solriamfetol 150 mg Oral Tablet
Drug
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2023 · Synced Oct 14, 2026, 3:31 PM EDT
Completed No phase listed Observational

Direct Referral for Apnea Monitoring

NCT05419323
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
6,501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
San Francisco, California • Portland, Oregon • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 14, 2026, 3:31 PM EDT