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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:54 AM EDT

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Showing 49–72 of 760 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea/Hypopnea Syndrome Clear all
Completed Phase 2 Interventional

Trial of AD113 and Atomoxetine in OSA Patients With Hypertension

NCT04905979
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertension
Interventions
AD113, Atomoxetine
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Towson, Maryland • Cincinnati, Ohio • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring

NCT02928770
View directory record Official record
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Nastent
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Oct 6, 2026, 10:54 AM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Recruiting No phase listed Observational

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

NCT07113288
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Inspire® UAS System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
5
States / cities
Colorado Springs, Colorado • Bradenton, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Results available

Hyperglycemic Profiles in Obstructive Sleep Apnea: Effects of PAP Therapy

NCT02454153
View directory record Official record
Conditions
Sleep Apnea, Diabetes
Interventions
REMStar Positive Airway Pressure, LifeStyle Counseling
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 6, 2026, 10:54 AM EDT
Completed No phase listed Observational

Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea

NCT02097212
View directory record Official record
Conditions
Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC), Obstructive Sleep Apnea (OSA)
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 29, 2017 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Early Phase 1 Interventional

Endothelial Function in Obstructive Sleep Apnea

NCT03122639
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Atorvastatin 10mg, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 6, 2026, 10:54 AM EDT
Terminated Not applicable Interventional

Pediatric Obesity Management Study

NCT05622981
View directory record Official record
Conditions
Obesity, Childhood, Behavior, Eating
Interventions
Age-specific educational materials and monitoring
Behavioral
Lead sponsor
Corewell Health East
Other
Eligibility
2 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Oct 6, 2026, 10:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Potential Mechanism of Exercise Impairment in OSA

NCT02505594
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
30 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 5, 2018 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Results available

Determining the Benefits of Improving Communication in BPAP/CPAP Users

NCT03795753
View directory record Official record
Conditions
Positive-Pressure Respiration, Communication
Interventions
F2S Communicator, Non-functioning Communicator
Device · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2020 · Synced Oct 6, 2026, 10:54 AM EDT
Active, not recruiting Not applicable Interventional

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

NCT03487185
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult, Preeclampsia, Obstetrical Complications
Interventions
Continuous Positive Airway Pressure, Sleep Advice Control
Device · Other
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
18 Years and older · Female only
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
14
States / cities
Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome

NCT00107809
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
60
States / cities
Birmingham, Alabama • Tucson, Arizona • Fort Smith, Arkansas + 51 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 6, 2026, 10:54 AM EDT
Not listed No phase listed Observational

Reiterative Development and Evaluation Study of OSA Therapy System

NCT01634074
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
ApniCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
7
States / cities
Burlingame, California • Redwood City, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 6, 2026, 10:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents

NCT01840618
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
Interventions
Nasal Continuous positive airway pressure (CPAP)
Device
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance

NCT00711516
View directory record Official record
Conditions
Excessive Sleepiness
Interventions
Armodafinil, Placebo
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Burlingame, California • San Diego, California • Stanford, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2013 · Synced Oct 6, 2026, 10:54 AM EDT
Terminated Early Phase 1 Interventional

CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia

NCT03972943
View directory record Official record
Conditions
CALR Gene Mutation, Essential Thrombocythemia, JAK2 Gene Mutation, MPL Gene Mutation, Obstructive Sleep Apnea Syndrome, Polycythemia Vera
Interventions
Continuous Positive Airway Pressure, Patient Observation, Questionnaire Administration
Procedure · Other
Lead sponsor
University of Utah
Other
Eligibility
30 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea

NCT04121923
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
696 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional Results available

Arrhythmia Detection In Obstructive Sleep Apnea (ADIOS)

NCT02743520
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmia, Stroke, Cardiovascular
Interventions
The Lifestar Act III
Device
Lead sponsor
University of Miami
Other
Eligibility
40 Years to 85 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional

Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery

NCT01697878
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
CPAP followed by atmospheric pressure, Atmospheric pressure followed by CPAP
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 6, 2026, 10:54 AM EDT
Recruiting Not applicable Interventional

Effectiveness of Audio Cues to Achieve Positional Therapy in Patients With Positional Obstructive Sleep Apnea

NCT07714330
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Positional Obstructive Sleep Apnea
Interventions
Investigational Positional Therapy Device
Device
Lead sponsor
SleepDev, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed No phase listed Observational

Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea

NCT04793334
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
sleeve gastectomy
Procedure
Lead sponsor
Brandon Nokes
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 6, 2026, 10:54 AM EDT
Completed No phase listed Observational

Screening Tools for Obstructive Sleep Apnea (OSA) in Hospitalized Medical Patients

NCT01340781
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Polysomnogram
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2013 · Synced Oct 6, 2026, 10:54 AM EDT
Completed Not applicable Interventional

Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease

NCT02034357
View directory record Official record
Conditions
Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
Interventions
Neurocognitive function, Sleep evaluations
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Oct 6, 2026, 10:54 AM EDT