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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obstructive Sleep Apnea Clear all
Terminated No phase listed Observational Results available

Prospective Study to Evaluate Outcomes From Transoral BOT Resection for OSAHS

NCT01107795
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Interventions
Transoral Robotic Surgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Jun 7, 2026, 6:28 AM EDT
Recruiting Not applicable Interventional

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

NCT02703207
View directory record Official record
Conditions
Obstructive Sleep Apnea, OSA COPD Overlap Syndrome
Interventions
Positive airway pressure, NIPPV and /or oxygen
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 7, 2026, 6:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mechanisms for Individual Differences in Hypertension in Obstructive Sleep

NCT03176732
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypertension
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jun 7, 2026, 6:28 AM EDT
Not listed Not applicable Interventional

CPAP Adherence Pilot Study Among African Americans

NCT05955287
View directory record Official record
Conditions
Sleep Apnea
Interventions
Telemonitoring, Peer Based, CPAP Education, Usual Care
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Jun 7, 2026, 6:28 AM EDT
Withdrawn Not applicable Interventional

Reproductive Aging and Obstructive Sleep Apnea

NCT01850992
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
30 Years to 70 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Non-Inferiority Study of the FRESCA Airbox Positive Airway Pressure System

NCT03999944
View directory record Official record
Conditions
Sleep Apnea
Interventions
positive airway pressure system
Device
Lead sponsor
FRESCA Medical
Industry
Eligibility
22 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
6
States / cities
St. Petersburg, Florida • Atlanta, Georgia • Gainesville, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Jun 7, 2026, 6:28 AM EDT
Recruiting Phase 3 Interventional

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571109
View directory record Official record
Conditions
Obesity, Overweight, Obstructive Sleep Apnoea
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
20
States / cities
Gilbert, Arizona • Bradenton, Florida • Naples, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 7, 2026, 6:28 AM EDT
Active, not recruiting Not applicable Interventional

Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea

NCT04932447
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertension
Interventions
Inspiratory Muscle Strength Training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Phase 2 Interventional

Managing Opioid Related Sleep Apnea With Acetazolamide

NCT06043830
View directory record Official record
Conditions
Sleep-Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea, Chronic Pain, Opioid Use
Interventions
Acetazolamide, Placebo
Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Phase 4 Interventional

Nasal Budesonide in Children With Rhinitis and/or Mild Obstructive Sleep Apnea Syndrome

NCT00560586
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Budesonide, placebo
Drug
Lead sponsor
University of Louisville
Other
Eligibility
6 Years to 12 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional

Sleep Apnea Video Education for CPAP (SAVE-CPAP)

NCT02553694
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Enhanced education, Usual education, Usual follow up, Enhanced follow up
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Phase 3 Interventional

Effect of Heated Humidity With Thermosmart™ Compared to an Intranasal Steroid in Improving Compliance and Nasal Symptoms in Patients Using Continuous Positive Airway Pressure

NCT00665977
View directory record Official record
Conditions
Obstructive Sleep Apnea, Nasal Congestion, Sinus Congestion
Interventions
Thermosmart & placebo, Placebo Device & Nasacort, Placebo Arm
Drug · Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
16 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 6, 2010 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Sleep Apnea Intervention for Cardiovascular Disease Reduction

NCT01261390
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Conservative Medical Therapy (CMT), Sham PAP (Sham), Active PAP with RT Support (Active-Beh), Active PAP with Behavioral Modification (Active+Beh)
Behavioral · Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 75 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jun 7, 2026, 6:28 AM EDT
Completed No phase listed Observational

Evaluation of Obstructive Sleep Apnea as a Risk Factor for Pulmonary Embolism

NCT00409045
View directory record Official record
Conditions
Obstructive Sleep Apnea, Pulmonary Embolism
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 4, 2007 · Synced Jun 7, 2026, 6:28 AM EDT
Not listed Not applicable Interventional

The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study

NCT01121445
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
NeilMed nose and sinus irrigation
Device
Lead sponsor
Bridgeport Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bridgeport, Connecticut
Source: ClinicalTrials.gov public record
Updated May 11, 2010 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment

NCT02538419
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
CPAP + Peer Support, CPAP + Individual Education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2019 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics

NCT02732795
View directory record Official record
Conditions
Pediatric Sleep Apnea, Obesity, Morphine Metabolism
Interventions
Morphine pharmacokinetic evaluation
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2019 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Phase 1Phase 2 Interventional Results available

DAW1033B2 in Obstructive Sleep Apnea

NCT03426631
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Placebo oral capsule, DAW1033B2 oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA

NCT02244957
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
Interventions
Bi-level positive airway pressure (BPAP), Nocturnal oxygen
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Effects of Continuous Positive Airway Pressure (CPAP) on Glucose Metabolism

NCT01503164
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep Apnea, Sleep-disordered Breathing
Interventions
Positive Pressure Therapy (PAP), LifeStyle Counseling
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 18, 2017 · Synced Jun 7, 2026, 6:28 AM EDT
Recruiting No phase listed Observational

SUNOSI® (Solriamfetol) Pregnancy Registry

NCT06413420
View directory record Official record
Conditions
Narcolepsy, Obstructive Sleep Apnea, Pregnant Women and Their Offspring
Interventions
Sunosi (solriamfetol), Other prescription wake-promoting medications or stimulants, No treatment
Drug · Other
Lead sponsor
Axsome Therapeutics, Inc.
Industry
Eligibility
Female only
Enrollment
1,731 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
2
States / cities
Morrisville, North Carolina • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Jun 7, 2026, 6:28 AM EDT
Completed No phase listed Observational

Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35

NCT01825278
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea
Interventions
ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Adherence to Electrical Glossal In Situ Stimulation for Sleep Apnea (AEGIS Study)

NCT04974515
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
eXciteOSA
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Jun 7, 2026, 6:28 AM EDT
Completed Not applicable Interventional Results available

Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)

NCT02522442
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Auto BiLevel
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Jun 7, 2026, 6:28 AM EDT