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ClinicalTrials.gov public records Last synced Oct 15, 2026, 9:29 AM EDT

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Showing 457–480 of 759 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Pharyngeal Muscle Control Mechanisms of Atomoxetine-plus-oxybutynin in Obstructive Sleep Apnea

NCT05944965
View directory record Official record
Conditions
OSA
Interventions
Atomoxetine 80 mg plus Oxybutynin 5 mg, Atomoxetine 80 MG, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 15, 2026, 9:29 AM EDT
Completed No phase listed Observational

World Trade Center (WTC) CHEST

NCT01466218
View directory record Official record
Conditions
Pulmonary Disease, Cardiac Disease, Cardiopulmonary Disease, Obstructive Sleep Apnea, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
40 Years and older
Enrollment
1,012 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2014 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Not applicable Interventional

Promoting Adherence to Sleep Apnea Treatment Among Blacks With Metabolic Syndrome

NCT01946659
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Adherence to Sleep Apnea Treatment, Standard Care Group
Behavioral · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2015 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Phase 2 Interventional

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

NCT05951023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eszopiclone 2 mg, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 15, 2026, 9:29 AM EDT
Not yet recruiting Not applicable Interventional

Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).

NCT07613281
View directory record Official record
Conditions
Snoring, OSA - Obstructive Sleep Apnea
Interventions
Palatal Implant System
Device
Lead sponsor
Serene Sleep, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California • Evans, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Terminated Not applicable Interventional Results available

Propofol vs Propofol + Benzo/Opiates in High Risk Group

NCT01315158
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Obesity
Interventions
Propofol Alone, Propofol+Benzo/Opioids
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 28, 2016 · Synced Oct 15, 2026, 9:29 AM EDT
Terminated Not applicable Interventional Results available

Remote Monitoring in Obstructive Sleep Apnea

NCT01678560
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Monitoring every 3 months by face-to-face visits, Frequent remote monitoring
Device
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Comparison of Physical Activity Regimens as Treatments for Obstructive Sleep Apnea

NCT00956423
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
moderate-intensity aerobic and resistance training, low-intensity stretching
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 55 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2011 · Synced Oct 15, 2026, 9:29 AM EDT
Withdrawn Not applicable Interventional

Positioning of Surgical Patients With Sleep Apnea

NCT02123238
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
bed positioning
Other
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Englewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 15, 2015 · Synced Oct 15, 2026, 9:29 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Effects of Mental Tasks on Breathing Patterns in Adults Using Chronic Opioids vs Non-opioid Users.

NCT07829055
View directory record Official record
Conditions
Opiod Use Disorder, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Recruiting Phase 2 Interventional

Down Syndrome Obstructive Sleep Apnea

NCT06043440
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Oxygen
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
5 Years to 18 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
7
States / cities
Los Angeles, California • Ann Arbor, Michigan • Cincinnati, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Completed No phase listed Observational

Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Device in the Diagnosis of Obstructive Sleep Apnea

NCT04778748
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Under-mattress sleep monitor
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Oct 15, 2026, 9:29 AM EDT
Recruiting No phase listed Observational

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

NCT06189755
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Positive Airway Pressure
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
500 participants
Timeline
2024 – 2028
U.S. locations
2
States / cities
Columbus, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Terminated Not applicable Interventional Results available

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

NCT01953874
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Sleep Disordered Breathing
Interventions
MV ASV, Optimized Medical Treatment
Device · Drug
Lead sponsor
ResMed
Industry
Eligibility
21 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
14
States / cities
Huntsville, Alabama • Los Angeles, California • Denver, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 15, 2026, 9:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea

NCT00672737
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Remifentanil, Cold pain threshold and tolerance, Heat pain threshold and tolerance, Polysomnography
Drug · Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 15, 2026, 9:29 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Assessment of PPG & PAT to Detect Upper Airway Obstruction in Patients With Obstructive Sleep Apnea

NCT01831583
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Measurement of PPG waveforms, Measurement of Pulse Arrival Time (PAT)
Device
Lead sponsor
Sotera Wireless, Inc.
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Escondido, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2013 · Synced Oct 15, 2026, 9:29 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.

NCT05592002
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Genio System
Device
Lead sponsor
Nyxoah S.A.
Industry
Eligibility
22 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
16
States / cities
Colorado Springs, Colorado • Boca Raton, Florida • Miami, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 15, 2026, 9:29 AM EDT
Active, not recruiting No phase listed Observational

A Prospective Observational Cohort to Study the Genetics of Obstructive Sleep Apnea and Associated Co-Morbidities

NCT01857427
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 70 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Withdrawn No phase listed Observational

Can Postoperative Outcomes be Predicted From Asking OSA Screening Questions Pre-operatively?

NCT02930538
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Survey
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
3 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Oct 15, 2026, 9:29 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

NCT03307330
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

NCT00371293
View directory record Official record
Conditions
Sleep Apnea Syndromes, Inflammation
Interventions
Weight Loss Program, CPAP therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 15, 2026, 9:29 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Pathogenesis of OSA in People Living With HIV

NCT03064204
View directory record Official record
Conditions
Obstructive Sleep Apnea, HIV/AIDS
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 79 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Not applicable Interventional Results available

Improving the Frequency and Quality of Sleep Apnea Care Management

NCT01916655
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Self-Management Care, Self-Management Mobile Care, Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 15, 2026, 9:29 AM EDT
Completed Phase 2 Interventional

Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health

NCT05616260
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Acetazolamide, Placebo, Continuous Positive Airway Pressure
Drug · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 15, 2026, 9:29 AM EDT