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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:14 AM EST

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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Ocular Anesthesia Clear all

Conditions: Pain
Interventions: Vitrase; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 18
States / cities: Newport Beach, California • Sacramento, California • Littleton, Colorado + 15 more

Conditions: Ocular Anesthesia
Interventions: Cryoanesthesia device, Lidocaine; Device · Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 99 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Corneal Injuries
Interventions: Eyeprotx™ General Anesthesia Protective Goggles, Eyelid Tape, Eye Ointment; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Anesthesia, Local, Intravitreal Injection, Macular Edema, Macular Degeneration, Diabetic Retinopathy, Diabetic Macular Edema
Interventions: Recens Cooling Anesthesia Device; Device
Lead sponsor: Recens Medical, Inc.; Industry
Eligibility: 18 Years to 110 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Reno, Nevada • Houston, Texas

Conditions: Anesthesia Complication
Interventions: Not listed
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pediatric Retinoblastoma, Retinoblastoma
Interventions: Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V), California Verbal Learning Test, Children's Version, Beery Developmental Test of Visual Motor Integration, 6th edition, Grooved Pegboard Test, Behavior Assessment System for Children/Parent Report; Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 6 Years to 17 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Anesthesia, Local
Interventions: AG-920, Proparacaine Ophthalmic; Drug
Lead sponsor: American Genomics, LLC; Industry
Eligibility: Up to 10 Years
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: McAllen, Texas

Conditions: Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
Interventions: High IOP Setting, Low IOP Setting; Device
Lead sponsor: Matthew Rauen; Other
Eligibility: 60 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: West Des Moines, Iowa

Conditions: Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
Interventions: TCD Measurement; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Stanford, California

Conditions: Corneal Diseases, Effectiveness of Microdrops
Interventions: Nanodropper and Proparacaine HCl 0.5%, Standard Eye Drop Bottle with Proparacaine HCl 0.5%; Combination Product
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Strabismus
Interventions: subtenons anesthetic - preservative-free bupivacaine 0.75%, topical anesthetic - 0.5 cc of lidocaine 3.5% ophthalmic gel, topical control - 0.5 cc of Hypromellose 0.3% gel, subtenons control - 0.5 cc of Normal Saline; Drug
Lead sponsor: Duke University; Other
Eligibility: 1 Year to 7 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease, Hyperparathyroidism
Interventions: Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline, Marcaine; Procedure · Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Antiseptic, Anesthesia, Local
Interventions: Chloroprocaine ophthalmic gel 3%; Drug
Lead sponsor: Harrow Inc; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Brandon, Florida

Conditions: Retinal Detachment, Proliferative Vitreoretinopathy, Retinoschisis
Interventions: Triamcinolone, Bupivicaine Hydrochloride; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Delirium
Interventions: Cognitive test + Pupillary measure; Combination Product
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 325 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Anesthesia, Local, Intravitreal Injection, Macular Degeneration, Diabetic Macular Edema
Interventions: Cooling Anesthesia; Device
Lead sponsor: Recens Medical, Inc.; Industry
Eligibility: 18 Years to 110 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Reno, Nevada • Houston, Texas

Conditions: Macular Degeneration, Diabetic Retinopathy, Retinal Vein Occlusion (RVO)
Interventions: Iheezo, Lidocaine pledget; Drug
Lead sponsor: Retina Consultants of Delmarva; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Easton, Maryland

Conditions: Glaucoma, Intraocular Pressure, Anesthesia
Interventions: Tono-pen XL Applanation tonometer + Ocu-film +; Drug
Lead sponsor: University of Miami; Other
Eligibility: 1 Year to 18 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 2
States / cities: Miami, Florida

Conditions: Anesthesia, Local
Interventions: AG-920, Placebo; Drug
Lead sponsor: American Genomics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 249 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 2
States / cities: Newport Beach, California • McAllen, Texas

Conditions: Upper Eyelid Surgery
Interventions: Hyaluronidase, 2 mL of lidocaine 2% with epinephrine 1:100,000 without rHuPH20; Drug · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions: Oral sedation, Placebo; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 60 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Anesthesia, Local
Interventions: AG-920, Placebo; Drug
Lead sponsor: American Genomics, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: McAllen, Texas

Conditions: Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:; Drug
Lead sponsor: Daniel Benjamin; Other
Eligibility: Up to 21 Years
Enrollment: 3,520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 43
States / cities: Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more

Conditions: Glaucoma
Interventions: Sterile commercially available bandage contact lens, Medical grade silicone of a thickness >100 µm, Medical grade silicone of a thickness <100 µm with blur tint, Standard tip in conjunction with a topical anesthetic; Diagnostic Test
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Evaluation of Vitrase as a Spreading Agent

Cryoanesthesia for Intravitreal Injections

Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.

Long Term Safety of Cooling Anesthesia for Intravitreal Injection

Perioperative Complications of Deep Extubation in Adults

Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population

The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage

Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block

Efficacy of Nanodropper-mediated Topical Anesthetic

Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine

Postoperative Pain Control Following Vitreoretinal Surgery

Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia

Cooling Anesthesia for Intravitreal Injection

Patient Comfort Following Intravitreal Injections Using Iheezo Versus Standard Anesthesia

The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops

A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution

Use of Recombinant Hyaluronidase Human is Effective for the Use of Local Blocks for Eyelid's Surgery

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Tolerability of an Anesthesia-free Tonometer Tip