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ClinicalTrials.gov public records Last synced Oct 18, 2026, 7:04 AM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Ocular Refraction Clear all
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Contact Lenses With New UV-blocker Manufactured With Different Techniques

NCT03475875
View directory record Official record
Conditions
Correction of Refraction Error, Attenuation of Bright Light
Interventions
senofilcon A TEST Lens, senofilcon A CONTROL Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
5
States / cities
Foster City, California • Jacksonville, Florida • Pickens, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 18, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Refractive Accuracy of "2WIN" and Portable Autorefractors

NCT04249505
View directory record Official record
Conditions
Refractive Error - Myopia Axial, Astigmatism, Accomodation, Visual Impairment, Hyperopia of Both Eyes
Interventions
"2WIN" Photoscreener, "Plusoptix A12", "Retinomax"
Device
Lead sponsor
Alaska Blind Child Discovery
Other
Eligibility
6 Months to 95 Years
Enrollment
708 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 18, 2026, 7:04 AM EDT
Terminated Phase 1 Interventional Results available

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema

NCT04292912
View directory record Official record
Conditions
Macular Edema
Interventions
GSK2798745
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
6
States / cities
Sacramento, California • Lake Worth, Florida • Winter Haven, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional

Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol

NCT07168564
View directory record Official record
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Direct Comparison of SVOne Obtained Refraction to Subjective Manifest Refraction

NCT03222661
View directory record Official record
Conditions
Refractive Errors
Interventions
Refraction
Diagnostic Test
Lead sponsor
Smart Vision Labs
Industry
Eligibility
12 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 18, 2026, 7:04 AM EDT
Active, not recruiting Not applicable Interventional

Validation of the Vision Trainer Clinical Decision-Support Software

NCT07773753
View directory record Official record
Conditions
Myopia
Interventions
Software Trainer
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Pediatric Refraction With SVOne Autorefractor

NCT02559271
View directory record Official record
Conditions
Ocular Refraction
Interventions
Not listed
Lead sponsor
Smart Vision Labs
Industry
Eligibility
5 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction

NCT04693247
View directory record Official record
Conditions
Refractive Errors, Vision Disorders
Interventions
EQ103
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Newark, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigational Study of Accommodation Triggering and Control to Allow for the Performance of Refraction Measurements

NCT03957408
View directory record Official record
Conditions
Accommodation
Interventions
Visual Stimuli
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
18 Years to 30 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Newark, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Smart Vision Labs Autorefractor

NCT02300116
View directory record Official record
Conditions
Ocular Refraction
Interventions
Not listed
Lead sponsor
Smart Vision Labs
Industry
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2015 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Phase 2 Interventional Results available

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

NCT05059041
View directory record Official record
Conditions
Down Syndrome, Refractive Errors
Interventions
Dilated Refraction, Non-Dilated Refraction
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 18, 2026, 7:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results

NCT01342393
View directory record Official record
Conditions
Refractive Error
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

At-home Testing Refraction Results With Best Corrected Visual Acuity (BCVA) Outcomes in Adults

NCT04820218
View directory record Official record
Conditions
Visual Impairment, Myopia, Hyperopia, Astigmatism
Interventions
With Try-on glasses
Device
Lead sponsor
EyeQue Corp.
Industry
Eligibility
30 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Newark, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Clinical Investigation of the Vision-R800 Device.

NCT04208750
View directory record Official record
Conditions
Myopia, Hyperopia, Astigmatism, Presbyopia
Interventions
Vision R-800 Phoropter, Standard Phoropter
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed Not applicable Interventional

Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction

NCT05049070
View directory record Official record
Conditions
Refractive Errors
Interventions
Mobile medical application to self administer a subjective refraction test, Standard of care refraction test
Diagnostic Test
Lead sponsor
1800 Contacts, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
12
States / cities
Beverly Hills, California • Petaluma, California • Pomona, California + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 18, 2026, 7:04 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Comparison of Contoura Vision Outcomes Programmed Using the Manifest Refraction Verses Using Phorcides Planning Software in Patients With Oblique Astigmatism

NCT05888337
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura LASIK with Phorcides planning strategy, Contoura LASIK with manifest refraction planning strategy
Device
Lead sponsor
Bismarck Lasik
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bismarck, North Dakota
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Toric Intraocular Lens Following Cataract Surgery

NCT01140477
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
Toric Accommodating Lens, Accommodating Lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 8, 2014 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate Effectiveness of Digital Refraction

NCT03502863
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Digital refraction, Manual Refraction
Device · Other
Lead sponsor
Visibly
Industry
Eligibility
22 Years to 55 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
3
States / cities
Fort Lauderdale, Florida • Nashville, Tennessee • Harlingen, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2018 · Synced Oct 18, 2026, 7:04 AM EDT
Terminated Phase 1Phase 2 Interventional

Enhancement of Emmetropization in Hyperopic Infants

NCT00574717
View directory record Official record
Conditions
Hyperopia, Hypermetropia, Farsightedness
Interventions
Spectacles
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
8 Weeks to 20 Weeks
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Results available

Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism

NCT01852084
View directory record Official record
Conditions
Astigmatism
Interventions
enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 18, 2026, 7:04 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser

NCT01441895
View directory record Official record
Conditions
Cataract, Dry Eye
Interventions
Not listed
Lead sponsor
Ophthalmic Consultants of Long Island
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 18, 2026, 7:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VisionApp - Refraction and Presbyopia

NCT07570602
View directory record Official record
Conditions
Presbyopia, Refractive Errors
Interventions
VisionApp
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 18, 2026, 7:04 AM EDT