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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Weakness, Hospital Acquired Condition
Interventions
Ambulation
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 1 Interventional Accepts healthy volunteers

Leg Heat Therapy in Elderly Individuals

NCT05543980
Conditions
Aging, Muscle Weakness
Interventions
Sham device, Leg heat therapy device
Device
Lead sponsor
Purdue University
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
West Lafayette, Indiana
Conditions
Bladder Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer, Fatigue, Lung Cancer, Lymphoma, Ovarian Cancer, Prostate Cancer
Interventions
exercise intervention, complementary or alternative medicine procedure, fatigue assessment and management, physical therapy
Behavioral · Procedure
Lead sponsor
University of Utah
Other
Eligibility
60 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Muscle Weakness, Critical Illness, Sarcopenia
Interventions
MPR and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Dietary Supplement
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
45 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Protective Arm Balance Responses

NCT06388434
Conditions
Old Age; Debility, Peripheral Neuropathy
Interventions
Protective Arm Balance Response Training
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
45 Years to 88 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Muscle Weakness, ICU-acquired Weakness
Interventions
HMB protein supplement (3g), Nutritional Supplement
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
Interventions
No Drug and no aspecific intervention
Other
Lead sponsor
Biophytis
Industry
Eligibility
65 Years to 95 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Gainesville, Florida • Boston, Massachusetts • New York, New York
Conditions
Muscle Weakness
Interventions
Healthy Moves for Aging Well (Healthy Moves), Active Mind for Aging Well (Active Mind)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years to 110 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Dual Task Perturbation Training for OAwMCI

NCT04938349
Conditions
Mild Cognitive Impairment, Old Age; Debility
Interventions
Dual task perturbation training
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years and older
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Cancer, Geriatric, Fatigue
Interventions
Walk With Ease
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Hip Fracture, Testosterone Deficiency, Muscle Weakness
Interventions
Testosterone gel
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Fracture, Infection, Depression, Gait Instability, Debility
Interventions
Home Visit
Other
Lead sponsor
Northwell Health
Other
Eligibility
65 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Staten Island, New York
Conditions
Weakness, Muscle, Delirium in Old Age, Muscle Atrophy or Weakness, Muscle Loss, Hospital Acquired Condition, Physical Disability, Physical Inactivity
Interventions
Yoomi Physical Therapy Software
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
65 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
Frail Elderly, Muscle Weakness
Interventions
3-Step Workout for Life
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
60 Years to 90 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Muscle Weakness, Muscular Atrophy
Interventions
exercise, testosterone
Procedure · Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
65 Years and older · Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2006
U.S. locations
1
States / cities
No. Little Rock, Arkansas
Conditions
Old Age; Debility
Interventions
In-Bed Resistance Training Device, Standard of Care
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
70 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

C-Protein in Fatigue and Aging

NCT05926219
Conditions
Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
Interventions
Fatiguing Exercise
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Critical Illness, Sarcopenia, ICU Acquired Weakness
Interventions
MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Combination Product
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 99 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Not listed Not applicable Interventional Accepts healthy volunteers

Hydraulic Resistance and Older Adults

NCT06353438
Conditions
Aging, Fall, Old Age; Debility, Muscle Weakness
Interventions
Exercise Program
Other
Lead sponsor
College of Staten Island, the City University of New York
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Brooklyn, New York
Enrolling by invitation Not applicable Interventional

RIC (Remote Ischemic Conditioning) in Older Individuals

NCT06476288
Conditions
Old Age, Mobility Limitation, Debility
Interventions
Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
Other
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Sarcopenia, Gait Disorders in Old Age, Muscle Weakness
Interventions
BIO101, Placebo
Drug
Lead sponsor
Biophytis
Industry
Eligibility
65 Years and older
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
19
States / cities
Banning, California • Garden Grove, California • San Diego, California + 15 more
Not listed Not applicable Interventional Accepts healthy volunteers

A Community-Based Falls Prevention Program for Adults At-Risk for Falls

NCT05771818
Conditions
Accidental Fall, Neurologic Disorder, Old Age; Debility, Healthy Aging
Interventions
Falls Prevention Program
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Miami, Florida
Conditions
Social Isolation, Depression, Anxiety, Debility
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
65 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois