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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Recruiting Not applicable Interventional

Multi-center Trial to Improve Nocturia and Sleep in Older Adults

NCT06110091
View directory record Official record
Conditions
Nocturia, Insomnia
Interventions
Integrated Behavioral Therapy Program, Health Education Program
Behavioral
Lead sponsor
Atlanta VA Medical Center
Federal
Eligibility
60 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional Results available

Anxiety in Older Veterans

NCT02400723
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Progressive Muscle Relaxation, Diaphragmatic Breathing, Psychoeducation (Placebo)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Jun 11, 2026, 5:03 AM EDT
Recruiting Early Phase 1 Interventional

Thiamine Intervention and Coronary Artery Bypass Grafting

NCT06326996
View directory record Official record
Conditions
Coronary Heart Disease, Coronary Artery Bypass Grafting
Interventions
Thiamine, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 4 Interventional Results available

Trial of Levomilnacipran in Geriatric Depression

NCT02466958
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
levomilnacipran, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Jun 11, 2026, 5:03 AM EDT
Active, not recruiting Phase 3 Interventional

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

NCT04994717
View directory record Official record
Conditions
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Interventions
Blinatumomab, Low-intensity chemotherapy regimen, SOC chemotherapy regimen
Drug
Lead sponsor
Amgen
Industry
Eligibility
40 Years to 100 Years
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
7
States / cities
Duarte, California • Orange, California • San Francisco, California + 4 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Clinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

NCT06919926
View directory record Official record
Conditions
Hippocampal Overactivity, Dementia
Interventions
AGB101, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Screening for Atrial Fibrillation in Elderly Women Older Than 70 Years

NCT05444335
View directory record Official record
Conditions
Atrial Fibrillation New Onset
Interventions
Wearable cardiac monitor -Zio patch
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
70 Years to 100 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 3 Interventional

Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

NCT05153317
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
ELX/TEZ/IVA, IVA
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
2 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
13
States / cities
Tucson, Arizona • Palo Alto, California • Aurora, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional

Medication Adherence in Hypertension Study

NCT00688350
View directory record Official record
Conditions
Hypertension
Interventions
Behavioral feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 2 Interventional

Comparison of MMFS Dosages in Older Adults

NCT03601169
View directory record Official record
Conditions
Anxiety, Depression, Sleep Quality, Cognitive Impairment
Interventions
Low Dose MMFS-205-SR, High Dose MMFS-205-SR, Placebo
Dietary Supplement
Lead sponsor
Neurocentria, Inc.
Industry
Eligibility
60 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 8, 2020 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 2 Interventional Results available

Selinexor (KPT-330) in Older Patients With Relapsed AML

NCT02088541
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML)
Interventions
Selinexor, Hydroxyurea, Ara-C
Drug
Lead sponsor
Karyopharm Therapeutics Inc
Industry
Eligibility
60 Years and older
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
26
States / cities
Los Angeles, California • Sacramento, California • Stanford, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Trial to Evaluate the Safety and Immunogenicity of a 20-Valent Pneumococcal Vaccine in Adults 65 Years of Age or Older With Prior Pneumococcal Vaccination

NCT03835975
View directory record Official record
Conditions
Pneumococcal Disease
Interventions
13vPnC, PPSV23, 20vPnC
Biological
Lead sponsor
Pfizer
Industry
Eligibility
65 Years and older
Enrollment
875 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
34
States / cities
Mobile, Alabama • Chandler, Arizona • Peoria, Arizona + 26 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2021 · Synced Jun 11, 2026, 5:03 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Recovery of Physical Function After Critical Illness In Older Adults

NCT07225257
View directory record Official record
Conditions
Sepsis, Acute Lung Injury(ALI)
Interventions
Not listed
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

We Walk Plus Study for Older Adults With Intellectual Disabilities

NCT04573530
View directory record Official record
Conditions
Intellectual Disability
Interventions
We Walk Plus Intervention
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
35 Years to 60 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • New Lenox, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional

Facilitating Optimal Routines in Aging

NCT03913637
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Strategy Training, Enhanced Usual Care
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Not listed Not applicable Interventional

Intervention to Support Participation in Regular Exercise in the Elderly (INSPIRE)

NCT02464254
View directory record Official record
Conditions
Chronic Illnesses
Interventions
Physical activity plus positive affect, Physical activity plus education
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years to 110 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional Results available

Yoga in Older Cardiac Patients

NCT06235658
View directory record Official record
Conditions
Cardiovascular Diseases in Old Age
Interventions
Gentle Yoga
Behavioral
Lead sponsor
Geunyeong Cha
Other
Eligibility
65 Years to 100 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional

Way to Cure HCV Adherence

NCT02472925
View directory record Official record
Conditions
Hepatitis C
Interventions
MedSignals Pill Box
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Rivaroxaban

NCT02220725
View directory record Official record
Conditions
Bleeding
Interventions
Andexanet, Placebo
Biological · Other
Lead sponsor
Portola Pharmaceuticals
Industry
Eligibility
50 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cypress, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional

The Preliminary Effects of Empower@Home

NCT05593276
View directory record Official record
Conditions
Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders, Mental Disorder
Interventions
Empower@Home
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Phase 2 Interventional Results available

Allogeneic Transplantation From Related Haploidentical Donors

NCT00185692
View directory record Official record
Conditions
Blood Cancer, Leukemia, Graft Versus Host Disease, Malignancy, CLL, NHL, Hodgkin's Disease, MDS
Interventions
non-myeloablative hematopoietic cell transplantation, Anti-Thymocyte Globulin, Cyclosporine, Mycophenolate Mofetil, G-CSF, Solumedrol, Acetaminophen, Diphenydramine, Hydrocortisone
Procedure · Drug
Lead sponsor
Stanford University
Other
Eligibility
12 Months and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Urinary Incontinence Treatment Study

NCT03057834
View directory record Official record
Conditions
Urinary Incontinence, Sarcopenia
Interventions
Pelvic floor muscle exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
70 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jun 11, 2026, 5:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study on Whether Tart Cherry Juice Can Reduce Oxidative Stress and Inflammation

NCT00847743
View directory record Official record
Conditions
Oxidative Stress, Antioxidant Capacity, Inflammation
Interventions
Tart Cherry Juice
Dietary Supplement
Lead sponsor
Kronos Longevity Research Institute
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 18, 2009 · Synced Jun 11, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional

Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain

NCT06632535
View directory record Official record
Conditions
Chronic Pain, Musculoskeletal Pain
Interventions
Chiropractic care, Group medical visits
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 11, 2026, 5:03 AM EDT