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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:17 AM EDT

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Showing 337–360 of 3,894 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adult Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Combined Exercise Trial

NCT04848038
View directory record Official record
Conditions
Healthy Aging
Interventions
Exercise
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years to 80 Years
Enrollment
282 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fairway, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional Results available

Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia

NCT01363258
View directory record Official record
Conditions
Care-resistant Behavior, Dementia
Interventions
Care-resistant mouth care (MOUTh), Evidence-based mouth care
Behavioral · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Bellefonte, Pennsylvania • Harrisburg, Pennsylvania • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 7, 2018 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 3 Interventional Results available

Vyvanse Adolescent Open-Label Safety and Efficacy Extension Study

NCT00764868
View directory record Official record
Conditions
ADHD
Interventions
Lisdexamfetamine Dimesylate (LDX)
Drug
Lead sponsor
Shire
Industry
Eligibility
13 Years to 17 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
45
States / cities
Little Rock, Arkansas • El Centro, California • Rolling Hills Estates, California + 40 more
Source: ClinicalTrials.gov public record
Updated Jun 14, 2021 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 3 Interventional

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Older Patients With Non-Hodgkin's Lymphoma

NCT00003150
View directory record Official record
Conditions
Lymphoma
Interventions
rituximab, CHOP regimen, cyclophosphamide, doxorubicin hydrochloride, prednisone, vincristine sulfate
Biological · Drug
Lead sponsor
Eastern Cooperative Oncology Group
Network
Eligibility
60 Years and older
Enrollment
630 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2006
U.S. locations
91
States / cities
Mobile, Alabama • Phoenix, Arizona • Tucson, Arizona + 60 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2013 · Synced Oct 25, 2026, 7:17 AM EDT
Recruiting Not applicable Interventional

Senior Center Medication Safety and Empowerment Curriculum

NCT07799610
View directory record Official record
Conditions
Older Adults, Medication and Supplement Use, Caregiver Awareness, Health Literacy, Empowerment, Patient, Knowledge
Interventions
Team Alice Medication Safety and Empowerment Curriculum (MedSEC)
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
55 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional

Text Message Reminders for Hearing Healthcare

NCT05438225
View directory record Official record
Conditions
Hearing Loss
Interventions
Automated text message reminder
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2023 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Immunogenicity and Safety of bioCSL Quadrivalent Influenza Vaccine (QIV) in Adults Aged 18 Years and Above.

NCT02214225
View directory record Official record
Conditions
Influenza, Human
Interventions
Quadrivalent Influenza Vaccine (QIV), Trivalent Influenza Vaccine (TIV-1), Trivalent Influenza Vaccine (TIV-2)
Biological
Lead sponsor
Seqirus
Industry
Eligibility
18 Years and older
Enrollment
3,484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
33
States / cities
Huntsville, Alabama • Los Angeles, California • San Diego, California + 29 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 2 Interventional

Cognitive Effects of Darifenacin and Oxybutynin Extended Release in Volunteers Aged 60 and Over

NCT00170768
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Darifenacin, Oxybutynin, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
60 Years and older
Enrollment
150 participants
Timeline
2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 23, 2008 · Synced Oct 25, 2026, 7:17 AM EDT
Terminated Phase 3 Interventional Results available

A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People

NCT01259297
View directory record Official record
Conditions
Cardiovascular Events
Interventions
Aliskiren, Amlodipine, Hydrochlorothiazide (HCTZ), Placebo for Aliskiren, Placebo for Amlodipine, Placebo for Hydrochlorothiazide (HCTZ)
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
65 Years and older
Enrollment
2,336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • Northridge, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional

TMS for PTSD and Blood Pressure

NCT05512143
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Hypertension
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
Lifespan
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional Results available

Reducing Treatment Risk in Older Adults With Diabetes

NCT04585191
View directory record Official record
Conditions
Type 2 Diabetes Treated With Insulin, Hypoglycemia, Primary Health Care, Polypharmacy
Interventions
Conversation Aid, Attention Control Educational Handout
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
75 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
San Francisco, California • San Leandro, California • Union City, California + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 25, 2026, 7:17 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Evaluate Spine Motion in Older Adults

NCT05364320
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 4 Interventional Results available

Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement

NCT01270620
View directory record Official record
Conditions
Obesity, Arthritis
Interventions
propofol, Desflurane
Drug
Lead sponsor
Pedro Paulo Tanaka
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults

NCT05764824
View directory record Official record
Conditions
Cognitive Decline, Nutrition, Healthy, Brain Injuries
Interventions
Blueberry powder, Controlled and matched powder
Dietary Supplement · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years to 99 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional

An Intuitive, Non-intrusive, Approach to Reduce Patient Harm From Inappropriate Dosing of High-risk Drugs in Older Adult Patients Across an Urban Safety Net Hospital System

NCT05218343
View directory record Official record
Conditions
Potentially Inappropriate Medications
Interventions
EHR-based "nudge" interventions
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
65 Years and older
Enrollment
8,640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2023 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tart Cherry Supplementation and Women's Bone Health Study

NCT04167150
View directory record Official record
Conditions
Osteoporosis, Postmenopausal, Osteoporosis, Age-Related
Interventions
tart cherry juice concentrate is a commercial product provided by King Orchards (Central Lake, MI)
Dietary Supplement
Lead sponsor
Oklahoma State University
Other
Eligibility
65 Years to 80 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Walnut and Immunity Study

NCT05915390
View directory record Official record
Conditions
Immune Response, Upper Respiratory Tract Infection
Interventions
walnuts, Habitual diet
Dietary Supplement
Lead sponsor
Loma Linda University
Other
Eligibility
55 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 25, 2026, 7:17 AM EDT
Terminated Phase 2 Interventional Results available

Bendamustine, Obinutuzumab, and Dexamethasone in Older Patients With Diffuse Large B-cell Lymphoma

NCT02420210
View directory record Official record
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
Bendamustine Hydrochloride, Obinutuzumab, Dexamethasone, Quality-of-Life Assessment, Laboratory Biomarker Analysis
Drug · Biological · Other
Lead sponsor
University of Chicago
Other
Eligibility
70 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 25, 2026, 7:17 AM EDT
Completed No phase listed Observational

Study to Collect Information About Invasive Disease Caused by Extraintestinal Pathogenic Escherichia Coli-2 (EXPECT-2)

NCT04117113
View directory record Official record
Conditions
E. Coli Infection
Interventions
Not listed
Lead sponsor
UMC Utrecht
Other
Eligibility
60 Years and older
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder

NCT00813735
View directory record Official record
Conditions
Insomnia
Interventions
Eszopiclone, Placebo, Escitalopram
Drug
Lead sponsor
Lehigh Center for Clinical Research
Other
Eligibility
65 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 3, 2012 · Synced Oct 25, 2026, 7:17 AM EDT
Recruiting Phase 3 Interventional

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

NCT07265674
View directory record Official record
Conditions
Advanced Biliary Tract Cancer, Biliary Tract Cancer (BTC)
Interventions
Nanvuranlat, Physician's Best Choice
Drug · Other
Lead sponsor
J-Pharma Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
18
States / cities
Duarte, California • Orange, California • Santa Monica, California + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Recruiting Not applicable Interventional

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

NCT06987890
View directory record Official record
Conditions
Lung Cancer (NSCLC), Geriatric Assessment, Stereotactic Body Radiation Therapy (SBRT)
Interventions
Practical Geriatric Assessment
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 2Phase 3 Interventional

Maximizing Independence at Home (MIND at Home)

NCT01283750
View directory record Official record
Conditions
Memory Disorders, Dementia
Interventions
care coordination
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years and older
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 6, 2018 · Synced Oct 25, 2026, 7:17 AM EDT
Completed Phase 2Phase 3 Interventional

Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders

NCT00462618
View directory record Official record
Conditions
Insomnia
Interventions
Quetiapine, Cogntive behavioral therapy
Drug · Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
60 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Oct 25, 2026, 7:17 AM EDT