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ClinicalTrials.gov public records Last synced Oct 25, 2026, 8:02 AM EDT

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Showing 361–384 of 3,894 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adult Clear all
Completed Not applicable Interventional Results available

Helping Invested Families Improve Veterans Experiences Study

NCT01777490
View directory record Official record
Conditions
Caregiver, Disabled Veterans, Referred to Long-term Care, Residing at Home, Hospice Ineligible
Interventions
Helping Invested Families Improve Veterans Experiences - Control, Helping Invested Families Improve Veterans Experiences - HI FIVES
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
484 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 28, 2019 · Synced Oct 25, 2026, 8:02 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

A Study of the Safety of PAZ-417 in Healthy Elderly Adults

NCT00663065
View directory record Official record
Conditions
Healthy
Interventions
PAZ-417
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 4, 2009 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults

NCT05377411
View directory record Official record
Conditions
Aging
Interventions
tDCS, cognitive training
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 25, 2026, 8:02 AM EDT
Completed No phase listed Observational

EMPOWER-PULM (PULMonary Outcomes in Older Adults Empowered With Movement to Prevent Obesity and Weight Regain)

NCT03621098
View directory record Official record
Conditions
Obesity, Pulmonary Disease, Dyspnea
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy and Immunogenicity of Norovirus GI.1/GII.4 Bivalent Virus-like Particle Vaccine in Adults

NCT02669121
View directory record Official record
Conditions
Healthy Volunteers
Interventions
NoV Placebo-matching Saline, NoV GI.1/GII.4 Bivalent VLP Vaccine
Biological
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 49 Years
Enrollment
4,748 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Great Lakes, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 25, 2026, 8:02 AM EDT
Active, not recruiting Not applicable Interventional

The Hope App Study

NCT05729516
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Hope App immersive learning and telehealth platform
Behavioral
Lead sponsor
See Yourself Health LLC
Other
Eligibility
65 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Beverly, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Patient Coach Support for Older Adults With Obesity

NCT06624163
View directory record Official record
Conditions
Obesity
Interventions
OHWL Clinic Activities (Standard of Care), Coach Activities
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years to 85 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

NCT03912233
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
VX-121, TEZ, VX-561, TEZ/IVA, IVA, Placebo
Drug
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
12
States / cities
Los Angeles, California • Oakland, California • Lexington, Kentucky + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Oct 25, 2026, 8:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Muscle Function and Size in Older Adults With Rotator Cuff Tear

NCT01459536
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Not listed
Lead sponsor
Wake Forest University
Other
Eligibility
60 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Phase 3 Interventional Results available

A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurological Condition

NCT01557244
View directory record Official record
Conditions
Urinary Bladder, Neurogenic
Interventions
Fesoterodine PR 4 mg, Fesoterodine PR 8 mg, Oxybutynin, Fesoterodine PR, Fesoterodine BIC 2 mg, Fesoterodine BIC 4 mg
Drug
Lead sponsor
Pfizer
Industry
Eligibility
6 Years to 17 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
18
States / cities
Tucson, Arizona • Orange, California • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional

Virtual Reality-based Exercise in Older Adults

NCT02043834
View directory record Official record
Conditions
Distorted; Balance, Motor Deficit
Interventions
Balance Training
Other
Lead sponsor
University of Arizona
Other
Eligibility
65 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 28, 2014 · Synced Oct 25, 2026, 8:02 AM EDT
Withdrawn Phase 3 Interventional

Does Administration of Etomidate and Propofol of the Anesthetic Induction of Elderly Hypertensive Patient Provide Superior Blood Pressure Stability in Response to Direct Laryngoscopy When Compared to Propofol or Etomidate Alone?

NCT01248234
View directory record Official record
Conditions
Hypertension
Interventions
propofol, Etomidate, Propofol and Etomidate
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
65 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 16, 2012 · Synced Oct 25, 2026, 8:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Functional Capacity in Older Adults With Short Session High Intensity Interval Training

NCT03750006
View directory record Official record
Conditions
Frailty
Interventions
Short session HIIT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2024 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults

NCT02266628
View directory record Official record
Conditions
Respiratory Syncytial Virus (RSV)
Interventions
RSV-F Vaccine, Saline Placebo
Biological
Lead sponsor
Novavax
Industry
Eligibility
60 Years and older
Enrollment
1,599 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
10
States / cities
Redding, California • Stockbridge, Georgia • Lenexa, Kansas + 7 more
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 25, 2026, 8:02 AM EDT
Recruiting Phase 3 Interventional

A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

NCT06807281
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Abrocitinib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
2 Years to 11 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
11
States / cities
Birmingham, Alabama • North Little Rock, Arkansas • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Calmer Life: Treating Worry Among Older Adults In Underserved, Low-income, Minority Communities

NCT02391363
View directory record Official record
Conditions
Anxiety
Interventions
Cognitive behavior treatment, Information and referral
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
50 Years and older
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2019 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Pea Hull Fibre Supplementation

NCT02778230
View directory record Official record
Conditions
Healthy
Interventions
Pea Fiber, Control
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
60 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Phase 4 Interventional Results available

Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine Surgery

NCT03112993
View directory record Official record
Conditions
Spine Surgery
Interventions
sugammadex, Neostigmine
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Early Phase 1 Interventional

Nitrate Supplementation and Cerebrovascular and Cognitive Function in Metabolic Syndrome

NCT05532423
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Beetroot Juice - Active, beetroot juice - Placebo
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 25, 2026, 8:02 AM EDT
Active, not recruiting No phase listed Observational

Vanderbilt Memory and Aging Project

NCT05372159
View directory record Official record
Conditions
Alzheimer Disease, Aging, Aged, 80 and Over, Biomarkers, Brain, Case-Control Studies, Cognitive Dysfunction, Neuropsychological Tests
Interventions
none, observational study
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 25, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Proactive Social Robot for Older Adults in Reducing Loneliness and Social Isolation

NCT03972787
View directory record Official record
Conditions
Loneliness, Mood, Quality of Life
Interventions
Proactive social robot
Device
Lead sponsor
Baycrest
Other
Eligibility
70 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 25, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fatty Acid Modulation of Brain Function in Older Adults

NCT06192407
View directory record Official record
Conditions
Aging
Interventions
High Oleic Acid Diet, High Palmitic Acid Diet
Dietary Supplement
Lead sponsor
University of Vermont
Other
Eligibility
65 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 25, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Ester And Salt (KEAS) in Older Adults

NCT06868719
View directory record Official record
Conditions
Salt; Excess, Hypertension, Aging, Inflammation, Blood Pressure
Interventions
No Salt, No β-OHB, High Salt, No β-OHB, High Salt, High β-OHB
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
50 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 25, 2026, 8:02 AM EDT
Not yet recruiting No phase listed Observational

Refining Risk Prediction Models for Older Adults Using Electronic Health Records

NCT06995365
View directory record Official record
Conditions
Predictive Modeling
Interventions
Risk Prediction Model
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 25, 2026, 8:02 AM EDT