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ClinicalTrials.gov public records Last synced Oct 27, 2026, 2:06 PM EDT

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Showing 601–624 of 3,899 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adult Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Phase 3 Safety and Immunogenicity Study of aQIV in Elderly Adults

NCT03314662
View directory record Official record
Conditions
Influenza, Human
Interventions
MF59-adjuvanted Quadrivalent Subunit Inactivated Egg-derived Influenza Vaccine (aQIV), Licensed MF59-adjuvanted Trivalent Subunit Inactivated Egg-derived Influenza Vaccine (aTIV-1), MF59-adjuvanted Trivalent Subunit Inactivated Egg-derived Influenza Vaccine Containing the Alternate B Strain (aTIV-2)
Biological
Lead sponsor
Seqirus
Industry
Eligibility
65 Years and older
Enrollment
1,778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
20
States / cities
Mobile, Alabama • Anaheim, California • Redding, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Oct 27, 2026, 2:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)

NCT01674296
View directory record Official record
Conditions
Obesity, Stress, Feeding Behavior, Physical Activity
Interventions
Not listed
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
40 Years to 60 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)

NCT03283462
View directory record Official record
Conditions
Mitochondrial Function, Bioenergetics, Muscle Function, Aging
Interventions
Mitopure, Placebo
Dietary Supplement
Lead sponsor
Amazentis SA
Industry
Eligibility
65 Years to 90 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 4 Interventional Results available

A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder

NCT00928070
View directory record Official record
Conditions
Overactive Bladder
Interventions
Fesoterodine, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
65 Years and older
Enrollment
566 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
125
States / cities
Birmingham, Alabama • Montgomery, Alabama • Green Valley, Arizona + 106 more
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 3 Interventional Results available

Study in Adult and Adolescent Subjects With PAR (Perennial Allergic Rhinitis)

NCT01134705
View directory record Official record
Conditions
Rhinitis, Allergic, Perennial
Interventions
Beclomethasone dipropionate hydrofluoroalkane HFA Nasal Aerosol, Placebo Nasal Aerosol
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
12 Years and older
Enrollment
474 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
35
States / cities
Los Angeles, California • Mission Viejo, California • San Diego, California + 30 more
Source: ClinicalTrials.gov public record
Updated May 23, 2012 · Synced Oct 27, 2026, 2:06 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

NCT05304351
View directory record Official record
Conditions
Herpes Zoster, Shingles
Interventions
Amezosvatein Antigen High Dose Arm A, Amezosvatein Antigen Low Dose Arm B, Shingrix, Amezosvatein Adjuvant Dose Arm D, Amezosvatein Adjuvant Dose Arm F, Amezosvatein Adjuvant Dose Arm H, Amezosvatein Adjuvant Dose Arm J, Amezosvatein Adjuvant Dose Arm L
Biological
Lead sponsor
Curevo Inc
Industry
Eligibility
50 Years and older
Enrollment
1,516 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
14
States / cities
Tempe, Arizona • Coral Gables, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 27, 2026, 2:06 PM EDT
Recruiting Not applicable Interventional

OASIS: Peer Support for T2DM in Appalachia (Peer Participant)

NCT06336122
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Peer Coach Training - Weekly, Peer Coach Training - Biweekly
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
55 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Bowling Green, Kentucky • Hazard, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Enrolling by invitation Phase 2 Interventional

Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women

NCT03430037
View directory record Official record
Conditions
Frail Elderly Syndrome
Interventions
Fisetin, Placebo oral capsule
Dietary Supplement · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Terminated Phase 2 Interventional Results available

Vorinostat and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia

NCT00673153
View directory record Official record
Conditions
Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Untreated Adult Acute Myeloid Leukemia
Interventions
gemtuzumab ozogamicin, vorinostat, laboratory biomarker analysis
Drug · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
60 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
4
States / cities
Stanford, California • Detroit, Michigan • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Oct 27, 2026, 2:06 PM EDT
Active, not recruiting Not applicable Interventional

The Effect of Clinic Visit Audio Recordings for Self-management in Older Adults

NCT05824572
View directory record Official record
Conditions
Diabetes
Interventions
Clinic visit audio recordings for self-management in older adults, Usual Care
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Manchester, New Hampshire • Nashville, Tennessee • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Early Phase 1 Interventional

A Pilot Study to Examine the Effects of Vitamin D Supplementation on Mitochondrial Bioenergetics in Older Adults

NCT02445066
View directory record Official record
Conditions
Low 25-hydroxyvitamin D Concentrations
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 27, 2026, 2:06 PM EDT
Active, not recruiting Not applicable Interventional

Population Health Approach to Optimizing Medications in Older Adults

NCT06110156
View directory record Official record
Conditions
Medication Adverse Effects, Older Adults (65 Years and Older), Polypharmacy, Polypharmacy Patients, Deprescribing
Interventions
Patient-tailored deprescribing assessment and intervention
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

The Efficient Brain Study

NCT02771366
View directory record Official record
Conditions
Metabolism - Cerebral Energy
Interventions
Fermented Papaya Preparation, Granulated Sugar
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2019 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Not applicable Interventional Results available

Modified Application of Cardiac Rehabilitation for Older Adults

NCT03922529
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiac Rehabilitation, Transition of Care
Interventions
MACRO-I, Usual Care
Behavioral · Other
Lead sponsor
Daniel Forman, MD
Other
Eligibility
70 Years and older
Enrollment
416 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
St Louis, Missouri • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein-Distinct Macronutrient-Equivalent Diet 2

NCT05581953
View directory record Official record
Conditions
Healthy Aging
Interventions
Omnivorous, No meat
Other
Lead sponsor
South Dakota State University
Other
Eligibility
65 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Brookings, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections

NCT00711802
View directory record Official record
Conditions
Skin Diseases, Infectious
Interventions
Daptomycin, Standard of Care (SOC)
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
1 Year to 17 Years
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
22
States / cities
Birmingham, Alabama • Oakland, California • Orange, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Ad26.COV2.S Administered as Booster Vaccination in Adults Who Have Previously Received Primary Vaccination With Ad26.COV2.S or BNT162b2

NCT04999111
View directory record Official record
Conditions
Coronavirus Disease
Interventions
Ad26.COV2.S
Biological
Lead sponsor
Janssen Vaccines & Prevention B.V.
Industry
Eligibility
18 Years and older
Enrollment
1,541 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
21
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 27, 2026, 2:06 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assessment of the BodyGuardian Remote Monitoring Platform in Elderly Healthy Subjects

NCT01808053
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
BodyGuardian remote health monitoring system
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 3 Interventional

Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture

NCT00046254
View directory record Official record
Conditions
Osteoporosis, Hip Fracture
Interventions
Zoledronic Acid
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
50 Years and older
Enrollment
2,127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
27
States / cities
Birmingham, Alabama • Eureka, California • La Mesa, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 2, 2012 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

NCT00004451
View directory record Official record
Conditions
Parkinson Disease
Interventions
Glucose
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1998
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 1, 2005 · Synced Oct 27, 2026, 2:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism

NCT07421830
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD)
Interventions
Wellness Enhancing Physical Activity for Young Children: Parent Version (WE PLAY for Parents)
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Study of Inactivated, Split-Virion Influenza Vaccine Compared With Standard Fluzone Vaccine in Elderly Subjects

NCT00388583
View directory record Official record
Conditions
Orthomyxoviridae Infection, Influenza, Myxovirus Infection
Interventions
Split, Inactivated, Trivalent Influenza Vaccine
Biological
Lead sponsor
Sanofi
Industry
Eligibility
65 Years and older
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
17
States / cities
Alabaster, Alabama • Tucson, Arizona • Fountain Valley, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2012 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Not applicable Interventional Results available

Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care Coordination

NCT05820295
View directory record Official record
Conditions
Cardiovascular Diseases, Myocardial Infarction, Atrial Fibrillation, Diabetes Mellitus, Heart Failure, Hyperlipidemias, Hypertension, Ischemic Heart Disease, Stroke, Transient Ischemic Attack
Interventions
Care coordination delivered based on perceived need, Care coordination delivered based on usual care (e.g. discharge from hospital)
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
65 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 27, 2026, 2:06 PM EDT
Completed Phase 2 Interventional

A Study to Assess the Efficacy and Safety of Daily OM-85 in Young Children With Recurrent Wheezing

NCT05857930
View directory record Official record
Conditions
Recurrent Wheezing, Wheezing Lower Respiratory Illness
Interventions
OM-85, Placebo
Drug
Lead sponsor
OM Pharma SA
Industry
Eligibility
6 Months to 72 Months
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
31
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 25 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 27, 2026, 2:06 PM EDT