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ClinicalTrials.gov public records Last synced Oct 3, 2026, 2:10 PM EDT

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Showing 49–72 of 3,867 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adults Clear all
Recruiting Phase 2 Interventional

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

NCT06799195
View directory record Official record
Conditions
Hematological Malignancies, Graft-versus-Host Disease (GVHD)
Interventions
Attenuated-dose Cyclophosphamide, High-dose Cyclophosphamide, Sirolimus, Mycophenolate Mofetil (MMF)
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
60 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide (NO) Homeostasis

NCT01137656
View directory record Official record
Conditions
Healthy
Interventions
Acetylcholine and Blood
Drug
Lead sponsor
Mark Gladwin
Other
Eligibility
18 Years to 50 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Results available

Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-1)

NCT03740737
View directory record Official record
Conditions
Infertility
Interventions
Follitropin delta, Placebo
Drug · Other
Lead sponsor
Ferring Pharmaceuticals
Industry
Eligibility
18 Years to 34 Years · Female only
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
23
States / cities
Tempe, Arizona • Encino, California • Farmington, Connecticut + 20 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

Anastrozole Administration in Elderly Hypogonadal Men

NCT00136695
View directory record Official record
Conditions
Hypogonadism
Interventions
anastrozole
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
60 Years and older · Male only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Building Resilience for Surgical Recovery

NCT06174701
View directory record Official record
Conditions
Psychosocial Functioning, Surgery, Older Adults, Physical Function, Postoperative Outcome, Depressive Symptoms
Interventions
Problem Solving Therapy (PST), Enhanced Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional

MBM and taVNS for Low Back Pain and Depressive Symptoms

NCT07415941
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
MBM, VNSM
Behavioral · Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults

NCT05822466
View directory record Official record
Conditions
Accidental Fall
Interventions
Virtual tai ji quan: moving for better balance intervention (V-TJQMBB), Virtual multimodal exercise intervention (V-Multimodal)
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
65 Years to 90 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Aspirin in Reducing Events in the Elderly

NCT01038583
View directory record Official record
Conditions
Functional Disability, Dementia, Heart Disease, Stroke, Cancer, Bleeding, Depression
Interventions
100 mg enteric-coated aspirin, Placebo
Drug
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
65 Years and older
Enrollment
19,114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2024
U.S. locations
33
States / cities
Birmingham, Alabama • Palo Alto, California • Washington D.C., District of Columbia + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 3, 2026, 2:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Safety of Three Formulations of Ketasyn Administered for 14 Days in Healthy Elderly

NCT00660088
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Ketasyn
Other
Lead sponsor
Cerecin
Industry
Eligibility
55 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Oct 8, 2008 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed No phase listed Observational

Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

NCT01366183
View directory record Official record
Conditions
Stage I Ovarian Cancer AJCC v6 and v7, Stage IA Fallopian Tube Cancer AJCC v6 and v7, Stage IB Fallopian Tube Cancer AJCC v6 and v7, Stage IC Fallopian Tube Cancer AJCC v6 and v7, Stage II Ovarian Cancer AJCC v6 and v7, Stage IIA Fallopian Tube Cancer AJCC v6 and v7, Stage IIB Fallopian Tube Cancer AJCC v6 and v7, Stage IIC Fallopian Tube Cancer AJCC v6 and v7, Stage III Ovarian Cancer AJCC v6 and v7, Stage III Primary Peritoneal Cancer AJCC v7, Stage IIIA Fallopian Tube Cancer AJCC v7, Stage IIIB Fallopian Tube Cancer AJCC v7, Stage IIIC Fallopian Tube Cancer AJCC v7, Stage IV Fallopian Tube Cancer AJCC v6 and v7, Stage IV Ovarian Cancer AJCC v6 and v7, Stage IV Primary Peritoneal Cancer AJCC v7
Interventions
Assessment of Therapy Complications, Carboplatin, Filgrastim, Paclitaxel, Pharmacological Study, Quality-of-Life Assessment, Questionnaire Administration
Procedure · Drug · Biological + 1 more
Lead sponsor
Gynecologic Oncology Group
Network
Eligibility
75 Years and older
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
357
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 245 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Different Formulations of an A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly

NCT00953524
View directory record Official record
Conditions
Influenza, Swine-origin A/H1N1 Influenza
Interventions
Monovalent Subvirion A/H1N1 Influenza vaccine (7.5 µg of HA), Monovalent Subvirion A/H1N1 Influenza vaccine (15 µg of HA), Monovalent Subvirion A/H1N1 Influenza vaccine (30 µg of HA), Normal saline solution (placebo)
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
18 Years and older
Enrollment
849 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
15
States / cities
Hoover, Alabama • Chandler, Arizona • Phoenix, Arizona + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Optimizing Medication Management by Older Adults Through the Med Wise Rx Community-based Program

NCT05751980
View directory record Official record
Conditions
Communication Research
Interventions
Med Wise Rx
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
65 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
Eau Claire, Wisconsin • Greendale, Wisconsin • Kenosha, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Early Phase 1 Interventional

Propranolol in Primary Progressive Aphasia

NCT06066710
View directory record Official record
Conditions
Aphasia, Primary Progressive
Interventions
Propranolol, Magnetic Resonance Imaging (MRI), Placebo
Drug · Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Sleep Amyloid, Slow WAve Race and Ethnicity Study

NCT03814603
View directory record Official record
Conditions
Alzheimer Disease
Interventions
PET-MR Scan, PiB
Procedure · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
60 Years to 75 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias

NCT07638046
View directory record Official record
Conditions
Older Adults With Elevated Dementia Risk
Interventions
Mindfulness-based walking, Walking-only
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Neurovascular Effects of Empagliflozin

NCT07799441
View directory record Official record
Conditions
Blood Pressure, Endothelial Dysfunction
Interventions
Empagliflozin (EMPA), Placebo
Drug · Other
Lead sponsor
Kanokwan Bunsawat
Other
Eligibility
45 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed No phase listed Observational

Outcomes Of Social Service Programs For Homebound Older Adults

NCT00248924
View directory record Official record
Conditions
Homebound, Elderly
Interventions
Social Services
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2008 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Telemedicine Monitoring of Nocturnal Incidents

NCT04328896
View directory record Official record
Conditions
Diabetes Mellitus, Type 1, Hypoglycemia
Interventions
CGM-Tele-monitoring
Other
Lead sponsor
University of Southern California
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Oct 3, 2026, 2:10 PM EDT
Terminated Phase 2 Interventional

Effects of Pycnogenol on Cardiac Fibrosis and Diastolic Dysfunction in Aged Hypertensive Subjects

NCT00952627
View directory record Official record
Conditions
Cardiac Fibrosis, Diastolic Dysfunction
Interventions
Pycnogenol, Placebo
Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
50 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 17, 2013 · Synced Oct 3, 2026, 2:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Elders Preserving Independence in the Community

NCT05381480
View directory record Official record
Conditions
Healthy Aging
Interventions
In-home Preventive Health Visits by Advanced Practice Nurse, On-site Evidence-based Physical Activity, Health and Wellness Classes
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
55 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

Pharmacokinetics and Pharacodynamics of GW642444 in Paedetric Subjects

NCT01453296
View directory record Official record
Conditions
Asthma
Interventions
GW642444, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
5 Years to 11 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
5
States / cities
Cypress, California • Huntington Beach, California • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 3, 2026, 2:10 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The Hurria Older PatiEnts (HOPE) With Breast Cancer Study

NCT01472094
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
City of Hope Medical Center
Other
Eligibility
65 Years and older
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2026
U.S. locations
17
States / cities
Duarte, California • New Haven, Connecticut • Chicago, Illinois + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed No phase listed Observational

Bictegravir in the Elderly Living With HIV (BICEP)

NCT05064020
View directory record Official record
Conditions
HIV-1-infection
Interventions
Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 1 Interventional

Care Partner-Assisted Diabetes Self-Management Through Linking Continuous Glucose Monitoring With Mobile Health: Improving Outcomes for Older Adults With Mild Cognitive Impairment

NCT05601583
View directory record Official record
Conditions
Type 2 Diabetes, Mild Cognitive Impairment
Interventions
Continuous Glucose Monitor (CGM)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
65 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 3, 2026, 2:10 PM EDT