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ClinicalTrials.gov public records Last synced Oct 6, 2026, 10:43 AM EDT

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Showing 97–120 of 3,869 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adults Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Three Different Doses of VAC52416 (ExPEC10V) in Adults Aged 60 to 85 Years in Stable Health

NCT03819049
View directory record Official record
Conditions
Extraintestinal Pathogenic Escherichia Coli Prevention
Interventions
ExPEC10V, ExPEC4V, Prevnar 13, Placebo
Biological
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
60 Years and older
Enrollment
836 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
12
States / cities
Huntsville, Alabama • Melbourne, Florida • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 6, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Exercise Adherence With App Technology for At-Risk Adults Living in Rural Kansas and Nebraska

NCT07171255
View directory record Official record
Conditions
Sedentary Middle Age and Older Aged Adults
Interventions
RemoteEx+ Programming
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
40 Years to 85 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Emporia, Kansas • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Five Session Unified Protocol for Older Adults With Emotional Distress and Reduced Mobility

NCT04837521
View directory record Official record
Conditions
Emotional Distress, Anxiety, Depression
Interventions
Unified Protocol
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Phase 4 Interventional Results available

Treating Hearing Loss to Improve Mood and Cognition in Older Adults

NCT03321006
View directory record Official record
Conditions
Hearing Loss, Depression
Interventions
Phonak Audeo B-R 90 hearing aid device (Active), Duloxetine or escitalopram, Audeo B-R 90 hearing aid device (Sham)
Device · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 6, 2026, 10:43 AM EDT
Active, not recruiting Not applicable Interventional

Senior Adult Hepatobiliary Prehab Study

NCT05921552
View directory record Official record
Conditions
Hepatobiliary Cancer, Cholangiocarcinoma, Liver Metastases
Interventions
Resistance Training, Aerobic Training
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery

NCT05685511
View directory record Official record
Conditions
Older Adults, Anxiety, Depression, Major Surgical Resection of a Thoracic Malignancy, Major Surgical Resection of an Abdominal Malignancy
Interventions
Behavioral Activation, Medication Optimization, Usual care resources
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Online Peer Networked Collaborative Learning for Managing Depressive Symptoms

NCT02841787
View directory record Official record
Conditions
Depression
Interventions
iCBT for late life depression
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
65 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 6, 2026, 10:43 AM EDT
Active, not recruiting Not applicable Interventional

Optimizing CBSST With Executive Function Training for Schizophrenia

NCT06251193
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
E-CBSST
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
60 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 6, 2026, 10:43 AM EDT
Terminated Phase 2 Interventional Results available

Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS

NCT01442714
View directory record Official record
Conditions
Leukemia, Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Interventions
Azacitidine, Lenalidomide
Drug
Lead sponsor
Stanford University
Other
Eligibility
60 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2018 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Phase 3 Interventional Results available

Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)

NCT00860847
View directory record Official record
Conditions
Coronary Atherosclerosis, Coronary Artery Calcification, Coronary Stenosis
Interventions
Aged garlic extract and Coenzyme Q10
Dietary Supplement
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
35 Years to 84 Years · Male only
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2015 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Brief App-based Mobile Health and Well-being Intervention Among Middle-aged Adults

NCT04272138
View directory record Official record
Conditions
Meditation, Control Group
Interventions
Calm Meditation, Educational Podcast Control
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
40 Years to 64 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 28, 2022 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effects of Strength Training on Knee Osteoarthritis

NCT00000406
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Progressive resistance exercise
Procedure
Lead sponsor
Indiana University
Other
Eligibility
60 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1977 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Oct 6, 2026, 10:43 AM EDT
Terminated Phase 4 Interventional

DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder

NCT02623504
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Carbamazepine, Placebo
Drug
Lead sponsor
Validus Pharmaceuticals
Industry
Eligibility
10 Years to 17 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
4
States / cities
Orlando, Florida • Baltimore, Maryland • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2023 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Phase 3 Interventional Results available

A Safety Study of Pimavanserin in Adult and Elderly Subjects Experiencing Neuropsychiatric Symptoms Related to Neurodegenerative Disease

NCT03575052
View directory record Official record
Conditions
Neuropsychiatric Symptoms Related to Neurodegenerative Disease
Interventions
Pimavanserin, Placebo
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
60 Years and older
Enrollment
784 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
21
States / cities
Gilbert, Arizona • Costa Mesa, California • Santa Ana, California + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Phase 2 Interventional Results available

Insomnia Treatment and EMA (Ecological Momentary Assessment) Outcomes

NCT05908526
View directory record Official record
Conditions
Insomnia
Interventions
Baseline surveys, Cognitive testing and EMAs, Actiwatch, suvorexant (or placebo), Placebo
Behavioral · Device · Drug + 1 more
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use

NCT05900115
View directory record Official record
Conditions
Substance Use, Parenting, Communication
Interventions
Media Ready Parent, Active Control Program
Behavioral
Lead sponsor
Innovation Research & Training
Other
Eligibility
10 Years and older
Enrollment
576 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Oct 6, 2026, 10:43 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

An Objective Assessment Tool for Evaluating Functioning in Older Adults

NCT06489847
View directory record Official record
Conditions
Alzheimer Disease
Interventions
SPPB++ Application
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Senior Change Makers Study: Improving Physical Activity Environments

NCT02944838
View directory record Official record
Conditions
Sedentary Lifestyle
Interventions
Senior Change Makers Advocacy Program, Senior Change Makers Physical Activity Program
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Video Gaming to Evaluate Front of Pack Labeling With Children

NCT03482336
View directory record Official record
Conditions
Child Obesity
Interventions
Four FOP label designs
Other
Lead sponsor
Michigan State University
Other
Eligibility
6 Years to 10 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Program in Primary Care

NCT05943509
View directory record Official record
Conditions
Deafness
Interventions
Alternative rehabilitation strategies, Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 10:43 AM EDT
Not listed Phase 2 Interventional

A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)

NCT01305499
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
Entinostat days 3, 10, 5AC, Entinostat days 10,17
Drug
Lead sponsor
Hetty Carraway
Other
Eligibility
60 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
4
States / cities
New Haven, Connecticut • Baltimore, Maryland • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 6, 2026, 10:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Outreach and Individualized Coaching Extension

NCT07836114
View directory record Official record
Conditions
Chronic Disease, Mild Cognitive Impairment
Interventions
Virtual Outreach and Individualized Coaching Extension
Other
Lead sponsor
Emory University
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 6, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease

NCT02331784
View directory record Official record
Conditions
Older Adults, Aging Brain
Interventions
Computerized Plasticity-based Software, Commercially available Video Game
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years to 79 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 6, 2026, 10:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults

NCT04396002
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
Life Space Questionnaire, Low Luminance Questionnaire, Contrast sensitivity under dim illumination, Visual field under dim illumination (MAIA), Macular Pigment Optical Density (MPOD), Dark Adaptation
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 6, 2026, 10:43 AM EDT