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ClinicalTrials.gov public records Last synced Sep 26, 2026, 6:11 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Older People Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV

NCT06001814
View directory record Official record
Conditions
Hiv, Cardiovascular Diseases
Interventions
One-Mind One-Heart, Education
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 26, 2026, 6:11 PM EDT
Active, not recruiting Not applicable Interventional

Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors

NCT05467410
View directory record Official record
Conditions
Critical Illness, Cognitive Impairment, Circadian Dysrhythmia, Intensive Care Unit Delirium, Aging, Older People
Interventions
COG-AM, COG-PM
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Not yet recruiting Not applicable Interventional

Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias

NCT07839286
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Mild Cognitive Impairment
Interventions
Jigsawdio Multisensory Puzzle Platform, Standard Jigsaw Puzzle Activity
Behavioral
Lead sponsor
Callahan-Young LLC DBA Jigsawdio
Industry
Eligibility
60 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV

NCT06586619
View directory record Official record
Conditions
Depressive Symptoms, Hiv
Interventions
Tai chi/qigong intervention group, Health Education group
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
50 Years to 75 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Phase 2 Interventional Results available

A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System

NCT05438602
View directory record Official record
Conditions
COVID-19
Interventions
Nirmatrelvir, Ritonavir, Placebo for nirmatrelvir, Placebo for ritonavir
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
25
States / cities
San Francisco, California • Washington D.C., District of Columbia • Doral, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2024 · Synced Sep 26, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Hybrid Group Singing

NCT07355192
View directory record Official record
Conditions
Coronary Artery Disease, Elderly
Interventions
group singing (hybrid format), instructional sing-along video series
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
55 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

NCT06125522
View directory record Official record
Conditions
Breast Cancer
Interventions
vepdegestrant, Samuraciclib
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
17
States / cities
Fayetteville, Arkansas • Rogers, Arkansas • Springdale, Arkansas + 9 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed No phase listed Observational

Develop and Validate a Self-Administered Instrument That Will Screen for Eating Disorder Symptoms in Persons Aged 12 and Older With Type 1 Diabetes.

NCT00948311
View directory record Official record
Conditions
Type 1 Diabetes, Eating Disorder
Interventions
Not listed
Lead sponsor
HealthPartners Institute
Other
Eligibility
12 Years and older
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 26, 2026, 6:11 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Sensitivity Among Older Adults Who Consume Alcohol

NCT07636447
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
Alcohol (Oral), Placebo Control
Other
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Project HOPEFUL: A PN-RCT With Implementation Science

NCT07475039
View directory record Official record
Conditions
Older Adults (50-90 Years), Mental Health, Depression and Suicide Ideation, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness
Interventions
Standardized and manualized warm calls from providers trained in the BE training, Standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed No phase listed Observational

Quality of Life of Older Patients Who Are Undergoing Treatment for Cancer and of Their Family Caregivers

NCT00255697
View directory record Official record
Conditions
Psychosocial Effects of Cancer and Its Treatment, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
psychosocial assessment and care, quality-of-life assessment
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
863 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Mobile Health Intervention to Support Healthful Diet

NCT05236712
View directory record Official record
Conditions
Frailty
Interventions
Mobile app
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Phase 1 Interventional

Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI)

NCT00817154
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
Interventions
HOPES-I
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
50 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Concord, New Hampshire • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 6, 2014 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Canadian Manufactured Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine Compared With U.S. Manufactured Td

NCT00601835
View directory record Official record
Conditions
Diphtheria, Tetanus
Interventions
Tetanus and Diphtheria Toxoids Adsorbed (Td) Vaccine
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
11 Years to 60 Years
Enrollment
3,651 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
2
States / cities
Oakland, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 26, 2026, 6:11 PM EDT
Terminated Phase 2 Interventional

Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes

NCT04409327
View directory record Official record
Conditions
COVID19
Interventions
RTB101, Placebo
Drug
Lead sponsor
Restorbio Inc.
Industry
Eligibility
65 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Middletown, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Sep 26, 2026, 6:11 PM EDT
Active, not recruiting Phase 2 Interventional

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

NCT04761770
View directory record Official record
Conditions
Myelodysplastic Syndrome, Myeloproliferative Neoplasms, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia, Myelodysplastic/Myeloproliferative Overlapping Syndrome
Interventions
Geriatric assessment (GA) pre-transplant, conditioning regimen, Allogeneic CD34+ selected stem cells
Other · Drug · Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
60 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep, Diet, Exercise and Older Persons

NCT05735353
View directory record Official record
Conditions
Cognitive Change, Cognitive Decline
Interventions
High-Speed Circuit Resistance Training, High-Speed Multidirectional Yoga
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
60 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Efficacy of the Quell Wearable Device for Chronic Overlapping Pain Conditions

NCT05540002
View directory record Official record
Conditions
Chronic Pain, Adults 21 and Older, Multiple Chronic Overlapping Pain Conditions, Hypersensitivity
Interventions
High Intensity Quell, Low Intensity Quell
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 26, 2026, 6:11 PM EDT
Recruiting Phase 3 Interventional

A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe Eczema

NCT07765888
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Tilrekimig, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Northridge, California • Panama City, Florida • St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

RESveratrol To Improve Outcomes in oldeR pEople With PAD (the RESTORE Trial)

NCT02246660
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Resveratrol, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
65 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2018 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Intensive Versus Standard Blood Pressure Lowering to Prevent Functional Decline in Older People

NCT01650402
View directory record Official record
Conditions
Hypertension, Systolic, Cerebrovascular Disease
Interventions
Anti-hypertensive therapy to SBP 130 mm Hg, Anti-hypertensive therapy to SBP 145 mm Hg
Other
Lead sponsor
UConn Health
Other
Eligibility
75 Years and older
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Phase 3 Interventional Results available

A 12-week Study to Compare the Efficacy and Safety of Albuterol Spiromax® Versus a Placebo in People 12 Years and Older With Persistent Asthma

NCT01424813
View directory record Official record
Conditions
Asthma
Interventions
Placebo MDPI, Albuterol MDPI
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
12 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
38
States / cities
Birmingham, Alabama • Phoenix, Arizona • Costa Mesa, California + 30 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2015 · Synced Sep 26, 2026, 6:11 PM EDT
Not yet recruiting Phase 3 Interventional

A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema

NCT07783425
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Tilrekimig, Dupilumab, Placebo for Tilrekimig, Placebo for Dupilumab
Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
12 Years and older
Enrollment
1,375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 26, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein

NCT03835416
View directory record Official record
Conditions
Prediabetes, Obesity
Interventions
Foods rich in high quality protein
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older · Male only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 26, 2026, 6:11 PM EDT