- Conditions
- Masseter Muscle Prominence
- Interventions
- BOTOX, Placebo
- Drug
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 207 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 20
- States / cities
- Los Angeles, California • Newport Beach, California • Vista, California + 14 more
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Showing 25–48
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- Conditions
- Nervous System Disorders
- Interventions
- Botulinum toxin type A
- Biological
- Lead sponsor
- Ipsen
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 258 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 13
- States / cities
- Downey, California • Fairfield, Connecticut • Boca Raton, Florida + 9 more
- Conditions
- Cervical Dystonia
- Interventions
- daxibotulinumtoxinA for injection
- Biological
- Lead sponsor
- Revance Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 357 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 37
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona • Fountain Valley, California + 32 more
- Conditions
- Lateral Canthal Lines
- Interventions
- Vehicle Control, RT001 (Botulinum Toxin Type A Topical Gel)
- Other · Drug
- Lead sponsor
- Revance Therapeutics, Inc.
- Industry
- Eligibility
- 30 Years to 55 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Antibiotic Stewardship, Overactive Bladder, Onabotulinumtoxin A, UTI
- Interventions
- No antibiotic, Prophylactic antibiotic, cystoscopic injection of onabotulinumtoxinA
- Other · Procedure
- Lead sponsor
- Benaroya Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Stony Brook, New York
- Conditions
- Muscle Spasticity, Stroke
- Interventions
- onabotulinumtoxinA, placebo (normal saline)
- Biological · Drug
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Glabellar Frown Lines
- Interventions
- DWP-450 (Botulinum purified neurotoxin, Type A)
- Biological
- Lead sponsor
- Evolus, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 570 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Chronic Migraine
- Interventions
- IncobotulinumtoxinA (XEOMIN®), OnabotulinumtoxinA (BOTOX®)
- Drug
- Lead sponsor
- Naval Medical Center Camp Lejeune
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Jacksonville, North Carolina
- Conditions
- Overactive Bladder
- Interventions
- onaBoNT-A
- Drug
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 184 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Neuropathic Back Pain, Spinal Cord Injury
- Interventions
- Botulinum Toxin A, Placebo
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Facial Flushing
- Interventions
- botulinum toxin A, Saline Control
- Drug · Other
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Urgency Urinary Incontinence
- Interventions
- Beta3-Agonists, Adrenergic [Mirabegron/Vibegron], OnabotulinumtoxinA 100 UNT [Botox]
- Drug
- Lead sponsor
- Women and Infants Hospital of Rhode Island
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 432 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2030
- U.S. locations
- 5
- States / cities
- Birmingham, Alabama • San Diego, California • Washington D.C., District of Columbia + 2 more
- Conditions
- Overactive Bladder
- Interventions
- Botulinum Toxin Type A 300U, Botulinum Toxin Type A 200U
- Biological
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 397 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 1
- States / cities
- Middlebury, Connecticut
- Conditions
- Pelvic Floor Disorders
- Interventions
- Botulinum neurotoxin, High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device
- Drug · Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 75 Years · Female only
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Cerebral Palsy
- Interventions
- Dysport Injectable Product
- Drug
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 5 Years to 17 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Hidradenitis Suppurativa (HS)
- Interventions
- Botulinum Toxin A (Allergan, Inc, Irvine CA), Placebo
- Drug
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 13 Years to 75 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Cerebral Palsy, Muscle Spasticity
- Interventions
- Botulinum toxin type A
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 3 Years to 12 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1997
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Benign Essential Blepharospasm, Hemifacial Spasm
- Interventions
- DaxibotulinumtoxinA
- Drug
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- The Bronx, New York
- Conditions
- Chronic Migraine
- Interventions
- Nerivio ®, Sham
- Device
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Scottsdale, Arizona
- Conditions
- Bladder Pain Syndrome, Female Sexual Dysfunction
- Interventions
- Onabotulinum toxin A, Conservative management (dietary and behavioral)
- Drug · Behavioral
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years to 99 Years · Female only
- Enrollment
- 159 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Neurogenic Bladder, Lower Urinary Tract Symptoms, Overactive Bladder, Neuro: Neurogenic Bladder, Neurogenic Detrusor Overactivity
- Interventions
- Standard number of injection sites, Reduced number of injection sites
- Procedure
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Overactive Bladder, Urinary Urge Incontinence, Urinary Incontinence, Detrusor Hyperreflexia, Urge Incontinence
- Interventions
- Botox Instillation, DMSO Instillation
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 1
- States / cities
- Jacksonville, Florida
- Conditions
- Primary Focal Hyperhidrosis of the Hands
- Interventions
- BTX-A
- Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- New Daily Persistent Headache
- Interventions
- OnabotulinumtoxinA
- Drug
- Lead sponsor
- St. Luke's-Roosevelt Hospital Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York