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Showing 1–16 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: One-Lung Ventilation Clear all
Completed Not applicable Interventional

Incentive Spirometry Prehabilitation Study

NCT03994848
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Spirometry Group
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 29, 2021 · Synced Jun 10, 2026, 7:39 PM EDT
Completed No phase listed Observational

Dexmedetomidine and Hypoxic Pulmonary Vasoconstriction in Thoracic Surgical Procedures and One-Lung Ventilation

NCT00839605
View directory record Official record
Conditions
Esophageal Cancer, Lung Cancer, Chest Wall Disorders
Interventions
Dexmedetomidine
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Jun 10, 2026, 7:39 PM EDT
Terminated Not applicable Interventional Results available

Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery

NCT01866657
View directory record Official record
Conditions
Hypoxia
Interventions
Vasoconstrictor Agents, Head/neck repositioning, Increase ETCO2, IV fluid bolus, Additional anesthesia, RBC transfusion, Increase FiO2
Drug · Other · Biological
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
65 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Jun 10, 2026, 7:39 PM EDT
Withdrawn Phase 4 Interventional

The Effect of Decreasing the Inspired Oxygen Concentration on Post-Operative Oxygenation After Primary Lobectomy

NCT02509182
View directory record Official record
Conditions
Hyperoxia
Interventions
60% oxygen, 100% oxygen
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Jun 10, 2026, 7:39 PM EDT
Completed No phase listed Observational

Respiratory Supports and COVID-19 Mortality

NCT04832061
View directory record Official record
Conditions
COVID-19
Interventions
Respiratory supports
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Jun 10, 2026, 7:39 PM EDT
Completed Not applicable Interventional

Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection

NCT04694638
View directory record Official record
Conditions
Prone Positioning, Covid19, Hypoxemic Respiratory Failure, ARDS, Non Invasive Ventilation, High Flow Nasal Cannulla
Interventions
Body position change
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 110 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Jun 10, 2026, 7:39 PM EDT
Withdrawn Not applicable Interventional

Individualized vs Low PEEP in One Lung Ventilation

NCT03569774
View directory record Official record
Conditions
One-Lung Ventilation, Obesity, Lung Diseases
Interventions
One-lung ventilation with individualized PEEP, One-lung ventilation with low PEEP
Procedure
Lead sponsor
Dionne Peacher
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 5, 2021 · Synced Jun 10, 2026, 7:39 PM EDT
Terminated No phase listed Observational Results available

Esophageal Pressure Measurements During One-lung Ventilation

NCT04725318
View directory record Official record
Conditions
Surgery, One-lung Ventilation
Interventions
One-lung ventilation
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jun 10, 2026, 7:39 PM EDT
Withdrawn Not applicable Interventional

Dolores One: Maximizing Functional Communication for Adults

NCT03934619
View directory record Official record
Conditions
Communication
Interventions
Dolores One
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Jun 10, 2026, 7:39 PM EDT
Completed No phase listed Observational

One Lung Ventilation

NCT01997073
View directory record Official record
Conditions
Evaluate the Changes in Respiratory Heat Content During One Lung Ventilation
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jun 10, 2026, 7:39 PM EDT
Completed Not applicable Interventional

Protective Ventilation With High Versus Low PEEP During One-lung Ventilation for Thoracic Surgery

NCT02963025
View directory record Official record
Conditions
One-Lung Ventilation
Interventions
PEEP level, Use of recruitment maneuvers
Procedure
Lead sponsor
Technische Universität Dresden
Other
Eligibility
18 Years and older
Enrollment
2,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Jun 10, 2026, 7:39 PM EDT
Completed No phase listed Observational

Intracuff Pressure During One-lung Ventilation in Infants and Children

NCT02424487
View directory record Official record
Conditions
One-lung Ventilation (OLV)
Interventions
Intracuff pressure measurement in one-lung ventilation during thoracic surgery
Procedure
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Jun 10, 2026, 7:39 PM EDT
Completed Not applicable Interventional Results available

One-Lung Ventilation in the Morbidly Obese Patient: Comparison of Double Lumen Versus Bronchial Blockers

NCT00813176
View directory record Official record
Conditions
Obesity
Interventions
Double Lumen Endotracheal Tube, Arndt Bronchial Blocker
Device
Lead sponsor
Javier H Campos
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2018 · Synced Jun 10, 2026, 7:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

VivaSight Double Lumen Tube for Single Lung Ventilation

NCT03690284
View directory record Official record
Conditions
Double Lumen Endotracheal Tube, Single Lung Ventilation
Interventions
Conventional Double Lumen Tube, VivaSight Double Lumen Tube
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Jun 10, 2026, 7:39 PM EDT
Completed Not applicable Interventional Results available

Ultrasound to Verify Lung-isolation During Single-lung Ventilation

NCT03729999
View directory record Official record
Conditions
Thoracic Diseases
Interventions
Portable, Point-of-Care Ultrasound
Device
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Jun 10, 2026, 7:39 PM EDT
Terminated No phase listed Observational

Effect of One-lung Ventilation on BIS Values

NCT03962036
View directory record Official record
Conditions
Surgery, Thoracic
Interventions
Bispectral index monitor
Device
Lead sponsor
Christopher McKee
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Jun 10, 2026, 7:39 PM EDT