- Conditions
- Open-Angle Glaucoma, Ocular Hypertension
- Interventions
- DE-104 medium concentration, DE-104 high concentration, Placebo, 0.005% latanoprost
- Drug
- Lead sponsor
- Santen Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 6
- States / cities
- Artesia, California • Pasadena, California • San Francisco, California + 3 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 229
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Glaucoma
- Interventions
- Observation only
- Other
- Lead sponsor
- Peregrine Ophthalmic
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Goose Creek, South Carolina
- Conditions
- Glaucoma
- Interventions
- Brinzolamide 1% and timolol 0.5% fixed combination eye drops
- Drug
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 20 Years and older
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Fort Worth, Texas
- Conditions
- Glaucoma
- Interventions
- Gen 2 Travoprost Intracameral Implant, Timolol eye drops 0.5%, Sham Procedure, placebo eye drops
- Drug · Procedure · Other
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 510 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- Dothan, Alabama
- Conditions
- Open-Angle Glaucoma
- Interventions
- XEN45 (Glaucoma Gel Stent)
- Device
- Lead sponsor
- AbbVie
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 74 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 23
- States / cities
- Fayetteville, Arkansas • Pasadena, California • Ventura, California + 19 more
- Conditions
- Glaucoma Open-Angle Primary, Glaucoma, Open Angle Glaucoma, Glaucoma, Open-Angle
- Interventions
- Mitomycin C
- Drug
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 20 Years to 85 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 4
- States / cities
- Arcadia, California • Fountain Valley, California • Los Angeles, California + 1 more
- Conditions
- Visual Field Defect, Peripheral, Glaucoma, Open-Angle
- Interventions
- Vitamin B3, Pyruvate, Placebo
- Dietary Supplement
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Open-angle Glaucoma or Ocular Hypertension
- Interventions
- DE-117 ophthalmic solution, latanoprost ophthalmic solution, Placebo
- Drug · Other
- Lead sponsor
- Santen Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 91 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 7
- States / cities
- Newport Beach, California • Morrow, Georgia • Kansas City, Missouri + 4 more
- Conditions
- Open Angle Glaucoma, Ocular Hypertension
- Interventions
- Travoprost Ophthalmic Topical Cream low-dose, Travoprost Ophthalmic Topical Cream mid-dose, Travoprost Ophthalmic Topical Cream high-dose, Timolol maleate ophthalmic solution, 0.5%, Travoprost Ophthalmic Solution, 0.004%
- Drug
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Open Angle Glaucoma, Ocular Hypertension
- Interventions
- PG324 Ophthalmic Solution 0.01%, PG324 Ophthalmic Solution 0.02%, Netarsudil (AR-13324) Ophthalmic Solution 0.02%, Latanoprost Ophthalmic Solution 0.005%
- Drug
- Lead sponsor
- Aerie Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 298 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 23
- States / cities
- Artesia, California • Inglewood, California • Newport Beach, California + 20 more
- Conditions
- Primary Open-angle Glaucoma (POAG), Ocular Hypertension
- Interventions
- SHP639 (n=60), Placebo Comparator (n=24)
- Drug
- Lead sponsor
- Shire
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Lexington, Massachusetts
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma; Drugs, Droopy Eyelid, Ptosis, Glaucoma, Primary Open Angle
- Interventions
- brimonidine tartrate ophthalmic solution 0.025%, sterile balanced saline solution
- Drug · Other
- Lead sponsor
- Tulane University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2036
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Glaucoma, Ocular Hypertension
- Interventions
- OTX-TP, Timolol
- Drug
- Lead sponsor
- Ocular Therapeutix, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Fayetteville, Arkansas
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Interventions
- Hydrus Microstent, Ophthalmic surgery
- Device · Procedure
- Lead sponsor
- Alcon Research
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 5
- States / cities
- Bentonville, Arkansas • Zephyrhills, Florida • Fraser, Michigan + 2 more
- Conditions
- Glaucoma, Open-Angle
- Interventions
- H-1337 Placebo, H-1337 [1], H-1337 [2], H-1337 [3]
- Drug
- Lead sponsor
- Allysta Pharmaceutical
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Goose Creek, South Carolina
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Pseudoexfoliation Syndrome
- Interventions
- Travatan, Azopt, Alphagan P
- Drug
- Lead sponsor
- Hermann Eye Center
- Other
- Eligibility
- 35 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2005
- U.S. locations
- 21
- States / cities
- Los Angeles, California • Hamden, Connecticut • Gainesville, Florida + 14 more
- Conditions
- Glaucoma, Open-Angle, Ocular Hypertension
- Interventions
- PF-04217329, latanoprost vehicle, latanoprost
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 8
- States / cities
- Cypress, California • Garden Grove, California • Gardena, California + 4 more
- Conditions
- Glaucoma Open-Angle Primary, Ocular Hypertension
- Interventions
- H-1337 1.0%
- Drug
- Lead sponsor
- D. Western Therapeutics Institute, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 17 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Newport Beach, California
- Conditions
- Glaucoma
- Interventions
- Triesence, balanced salt solution BSS
- Drug
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Glaucoma, Ocular Hypertension
- Interventions
- RKI983
- Drug
- Lead sponsor
- Novartis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Timeline
- Started 2007
- U.S. locations
- 5
- States / cities
- Artesia, California • Rochester, New York • Charlotte, North Carolina + 2 more
- Conditions
- Open Angle Glaucoma
- Interventions
- Streamline Surgical System, iStent Inject W
- Device
- Lead sponsor
- New World Medical, Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 18
- States / cities
- Fayetteville, Arkansas • Newport Beach, California • Torrance, California + 15 more
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension
- Interventions
- T-2345, Xalatan
- Drug
- Lead sponsor
- Nephron Pharmaceuticals Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 335 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- El Paso, Texas
- Conditions
- Glaucoma, Open-Angle [C11.525.381.407]
- Interventions
- Open angle glaucoma - iDropper device
- Device
- Lead sponsor
- Care Team Solutions
- Industry
- Eligibility
- 21 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Glaucoma, Open-angle, Ocular Hypertension (OHT), Phacoemulsification Cataract Surgery
- Interventions
- iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgery, Sham procedure in conjunction with cataract surgery
- Combination Product · Procedure
- Lead sponsor
- Glaukos Corporation
- Industry
- Eligibility
- 45 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Kenosha, Wisconsin