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ClinicalTrials.gov public records Last synced Nov 5, 2026, 5:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 489 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Ophthalmic Surgery Clear all

Conditions: Refractive Error, Glaucoma, Cataracts, Clear Lens Exchange
Interventions: Intervention; Device
Lead sponsor: Johnson & Johnson Surgical Vision, Inc.; Industry
Eligibility: Not listed
Enrollment: 1,674 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 4
States / cities: Dothan, Alabama • Bakersfield, California • Bloomington, Minnesota + 1 more

Conditions: Cataract
Interventions: UNITY Vitreoretinal Cataract System, CENTURION Vision System with Active Sentry, Anterior segment ophthalmic surgery; Device · Procedure
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 5
States / cities: West Des Moines, Iowa • Sioux Falls, South Dakota • Spring, Texas + 2 more

Conditions: Cataract
Interventions: Intraocular Lens (IOL); Device
Lead sponsor: Lenstec Incorporated; Industry
Eligibility: 21 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Tarpon Springs, Florida

Conditions: Cataract, Inflammation, Surgery
Interventions: Mapracorat, Vehicle; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 360 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Cataract, Floppy Iris Syndrome
Interventions: DisCoVisc, Healon5; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Cataract, Anterior Chamber Inflammation, Pain, Postoperative
Interventions: Dexamethasone phosphate, Placebo; Combination Product · Other
Lead sponsor: Eyegate Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Post Surgical Ocular Inflammation and Pain
Interventions: KPI-121 1% Ophthalmic Suspension dosed BID, Vehicle of KPI-121 Ophthalmic Suspension dosed BID; Drug
Lead sponsor: Kala Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 520 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 35
States / cities: Chandler, Arizona • Phoenix, Arizona • Artesia, California + 32 more

Conditions: Cataract
Interventions: Dexycu intracameral dexamethasone, Prednisolone Acetate; Drug
Lead sponsor: Research Insight LLC; Industry
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Laguna Hills, California • Garden City, New York

Conditions: Hyperopia
Interventions: TENEO 317 Model 2 excimer laser; Device
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 22 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 9
States / cities: Newport Beach, California • Fort Myers, Florida • Bloomington, Minnesota + 6 more

Conditions: Ocular Inflammation
Interventions: KPI-121 1%, Prednisolone acetate; Drug
Lead sponsor: Kala Pharmaceuticals, Inc.; Industry
Eligibility: Up to 3 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 4
States / cities: Palo Alto, California • Detroit, Michigan • Erie, Pennsylvania + 1 more

Conditions: Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
Interventions: Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL); Device
Lead sponsor: Eyegate Pharmaceuticals, Inc.; Industry
Eligibility: 22 Years to 50 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Myopia
Interventions: SMILE, LASIK; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 22 Years to 59 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Anesthesia Complication
Interventions: Not listed
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cataract, Diabetes, Hypertension, Obesity, Vision Disability
Interventions: Cataract surgery; Procedure
Lead sponsor: University of Pikeville; Other
Eligibility: 60 Years and older
Timeline: 2023
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Laser Corneal Surgery
Interventions: LASIK surgery, No Intervention; Procedure · Other
Lead sponsor: Deb Grzybowski; Other
Eligibility: 18 Years to 60 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2012
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Inflammation
Interventions: Difluprednate, Placebo; Drug · Other
Lead sponsor: Sirion Therapeutics, Inc.; Industry
Eligibility: 2 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Cataract, Astigmatism
Interventions: Conventional, Refractive Cataract Suite (Verion + ORA); Device
Lead sponsor: Carolina Eyecare Physicians, LLC; Other
Eligibility: 50 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Mt. Pleasant, South Carolina

Conditions: Bilateral Cataract
Interventions: ISBCS, DSBCS; Procedure
Lead sponsor: Sloan W. Rush, MD; Other
Eligibility: 30 Years to 100 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2022
U.S. locations: 1
States / cities: Amarillo, Texas

Conditions: Myopia, Astigmatism
Interventions: LASIK with the iFS femtosecond laser; Procedure
Lead sponsor: Stanford University; Other
Eligibility: Not listed
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Stanford, California

Conditions: Extraocular Extension Melanoma, Metastatic Intraocular Melanoma, Recurrent Intraocular Melanoma, Recurrent Melanoma, Stage IIIA Intraocular Melanoma, Stage IIIA Melanoma, Stage IIIB Intraocular Melanoma, Stage IIIB Melanoma, Stage IIIC Intraocular Melanoma, Stage IIIC Melanoma, Stage IV Intraocular Melanoma, Stage IV Melanoma
Interventions: axitinib, laboratory biomarker analysis; Drug · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Recurrent Ptosis of the Breast
Interventions: Seri Surgical Scaffold; Device
Lead sponsor: Bengtson Center; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 2
States / cities: Grand Rapids, Michigan

Conditions: Glaucoma, Glaucoma Following Surgery
Interventions: Digital microscope integrated with intraoperative OCT (Zeiss Artevo 800, Carl Zeiss Meditec AG), Spectralis Anterior-segment OCT (AS-OCT) (Heidelberg Engineering); Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Ocular Inflammation and Pain After Cataract Surgery
Interventions: APP13007, 0.05%, Matching Vehicle Placebo for APP13007, 0.05%; Drug
Lead sponsor: Formosa Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 370 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 31
States / cities: Chandler, Arizona • Mesa, Arizona • Phoenix, Arizona + 28 more

Conditions: Glaucoma
Interventions: Ranibizumab; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Search by objective public record fields.

A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Products

A Cataract Surgery Clinical Trial

Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing

Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

Intraoperative Floppy Iris Syndrome

Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain

A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%

Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without Astigmatism

KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children

Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")

A Prospective, Contralateral, Eye to Eye Comparison of SMILE Surgery to LASIK Surgery

Perioperative Complications of Deep Extubation in Adults

A (Prospective/Pilot) Study Evaluating the Effect of Cataract Surgery on the Daily Activity Levels of Elderly Patients

Corneal Biomechanics With Hydration in Normal and LASIK Eyes

Study of Difluprednate in the Treatment of Inflammation Following Ocular Surgery (ST-601-003)

Conventional Surgery vs. Verion/VerifEye

Immediate Simultaneous Bilateral Cataract Surgery

An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness

Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery

Seri Surgical Scaffold Support of the Lower Pole of the Breast

Anterior-segment OCT (AS-OCT) and Intraoperative OCT (iOCT) for Trans- Conjunctival Needle Revision (TCNR)

Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery Including a Corneal Endothelial Cell Sub-study

Ranibizumab in Preventing Failure of Ahmed Valve Glaucoma Surgery