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ClinicalTrials.gov public records Last synced Nov 7, 2026, 4:53 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 163 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Optical Imaging Clear all

Conditions: Peripheral Arterial Disease
Interventions: Pantheris System; Device
Lead sponsor: Avinger, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 20
States / cities: Jonesboro, Arkansas • Little Rock, Arkansas • West Hollywood, California + 16 more

Conditions: Melanoma
Interventions: Indocyanine Green (IC-Green), Imaging; Drug · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Pancreatic Cysts
Interventions: Direct visualization and needle based confocal laser-induced endomicroscopy miniprobe; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 1
States / cities: Orange, California

Conditions: Breast Cancer
Interventions: Diffuse Optical Spectroscopy Imaging; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Irvine, California

Conditions: Breast Cancer, HER2-positive Breast Cancer, TNBC - Triple-Negative Breast Cancer, HER2-negative Breast Cancer, Invasive Breast Carcinoma
Interventions: NearWave monitoring; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Carcinoma, Basal Cell
Interventions: Treatment of basal cell carcinoma with Nd:YAG laser under imaging guidance of optical coherence tomography (OCT); Device
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 105 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Breast Cancer
Interventions: DBT-TOBI, MRI-TOBI; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Gastrointestinal Disease, Gastrointestinal Dysfunction
Interventions: Biopsy imaged by Optical imaging device.; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Glaucoma
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 40 Years to 79 Years
Enrollment: 832 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2015
U.S. locations: 5
States / cities: Los Angeles, California • Miami, Florida • Boston, Massachusetts + 2 more

Conditions: Coronary Artery Disease
Interventions: Rosuvastatin; Drug
Lead sponsor: General University Hospital, Prague; Other
Eligibility: 18 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Maywood, Illinois • Iowa City, Iowa

Conditions: Glaucoma, Ocular Hypertension
Interventions: Netarsudil Ophthalmic Solution (Rhopressa), Artificial Tears (AT); Drug · Other
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Brain Tumor
Interventions: Panitumumab-IRDye800, Pinpoint-IR9000 endoscopic/handheld device, Explorer Air camera, PDE-NEO-II; Drug · Device
Lead sponsor: Stanford University; Other
Eligibility: 6 Months to 25 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Stanford, California

Conditions: Meningioma, Glioblastoma, Acoustic Neuroma, Brain Cancer, Pituitary Adenoma
Interventions: Panitumumab-IRDye800; Drug
Lead sponsor: Eben Rosenthal; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Thyroid Cancer
Interventions: Cerenkov luminescence imaging.; Diagnostic Test
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Biliary Stricture
Interventions: MGH Optical Frequency Domain Imaging (OFDI); Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Tissue Pain
Interventions: Soft tissue manipulation; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Port-Wine Stain, Rosacea, Telangiectasia, Angioma
Interventions: Optical Coherence Tomography; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 4 Years and older
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Irvine, California

Conditions: Pregnancy
Interventions: Optical coherence tomography; Diagnostic Test
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 90 participants
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Epilepsy
Interventions: Intrinsic signal imaging of human cortex; Diagnostic Test
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 6 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Hydration
Interventions: Hydration assessment via mobile app; Other
Lead sponsor: PepsiCo Global R&D; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Undergoing Esophagogastroduodenoscopy (EGD)
Interventions: NvisionVLE Imaging System: NvisionVLE Imaging Console, NvisionVLE Optical Probe and Inflation Accessory Kit; Device
Lead sponsor: NinePoint Medical; Industry
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Brain Tumor
Interventions: Speckle-Contrast Imaging; Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Not listed
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Eye Diseases, Retinal Disease, Glaucoma, Optic Nerve Diseases
Interventions: Auto-aligned OCT; Device
Lead sponsor: Duke University; Other
Eligibility: 1 Month and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Breast Cancer
Interventions: Optical Imaging; Device
Lead sponsor: Steven Isakoff, MD, PhD; Other
Eligibility: 18 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Evaluation of the Pantheris Atherectomy System

Nuclear and Near-Infrared (NIR) Imaging in Melanoma

Diagnosis of Pancreatic Cysts: Endoscopic Ultrasound With Fine Needle Aspiration (EUS/FNA), Direct Visualization, and Confocal Laser-induced Endomicroscopy-A Pilot Study

Monitoring and Predicting Breast Cancer Neoadjuvant Chemotherapy Response Using Diffuse Optical Spectroscopic Imaging

NearWave Optical Molecular Monitoring

Laser Treatment of Basal Cell Carcinoma Under Imaging Guidance

A Pilot Study of Tomographic Optical Breast Imaging (DBT-TOBI) to Monitor Response to Neoadjuvant Therapy

Optical Imaging of Gastrointestinal Biopsy Samples and Their Correlation With Histology

Advanced Imaging for Glaucoma Study

The Prediction of Extent and Risk Profile of Coronary Atherosclerosis and Their Changes During Lipid-lowering Therapy Based on Non-invasive Techniques

Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures

A Study of Optical Imaging With Light From Radiotracers in Cancer Patients

Optical Frequency Domain Imaging (OFDI) for Biliary Stricture Imaging

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness

Skin Imaging to Inform Laser Treatments

Retinal Vascular Changes During Pregnancy

Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

Feasibility of Using the Gatorade Sports Science Institute (GSSI) Labs App for Hydration Related Outcomes

High Resolution Optical Imaging of the Esophagus Using the NvisionVLE™ Imaging System

Intraoperative Optical Imaging of Brain Function

Advancing Pediatric Retinal Imaging With Auto-aligned OCT

TOBI to Monitor Response to Neoadjuvant Therapy in Breast Cancer