Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:08 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 163 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Optical Imaging Clear all

Conditions: Barrett's Esophagus
Interventions: MGH OFDI Imaging; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Glaucoma, Diabetic Retinopathy, Age-Related Macular Degeneration, Central Retinal Vein Occlusion, Branch Retinal Vein Occlusion
Interventions: Optical Coherence Tomography; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Irvine, California

Conditions: Celiac Disease, Healthy
Interventions: OFDI Capsule; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 16 Years and older
Enrollment: 108 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2028
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer
Interventions: Diffuse Optical Spectroscopy Imaging; Device
Lead sponsor: University of California, Irvine; Other
Eligibility: 21 Years to 75 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2018
U.S. locations: 3
States / cities: Costa Mesa, California • Irvine, California • Orange, California

Conditions: Dehydration
Interventions: GENPOP ad libitum fluid intake, GENPOP fluid restriction, ATHLETE ad libitum fluid intake, ATHLETE restricted fluid intake; Other
Lead sponsor: PepsiCo Global R&D; Industry
Eligibility: 14 Years to 65 Years
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 4
States / cities: Bradenton, Florida • Chicago, Illinois • Valhalla, New York + 1 more

Conditions: Barrett's Esophagus With or Without Dysplasia, Patients With Early Esophageal or Gastric Cancer, Patients With Intestinal Metaplasia of the Stomach
Interventions: Not listed
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Orange, California

Conditions: Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG)
Interventions: Nicotinamide, Standard Glaucoma Therapy; Drug · Other
Lead sponsor: University of Chicago; Other
Eligibility: 40 Years to 80 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2030
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Celiac Disease
Interventions: MGH OFDI Imaging; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 7 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Basal Cell Carcinoma
Interventions: Optical Coherence Tomography (OCT), Curettage & Desiccation (C&D) Procedure; Device · Procedure
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Colonic Polyps
Interventions: MGH Optical Frequency Domain Imaging (OFDI) System; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Multiple Sclerosis, Chronic Progressive
Interventions: lipoic acid, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years to 70 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Retinopathy of Prematurity
Interventions: Handheld Optical Coherence Tomography with OCT Angiography; Device
Lead sponsor: Duke University; Other
Eligibility: Up to 2 Months
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Durham, North Carolina • Philadelphi, Pennsylvania

Conditions: Retinal Diseases, Optic Nerve Diseases
Interventions: Duke Biomedical Engineering's Long-working distance OCT; Device
Lead sponsor: Duke University; Other
Eligibility: 6 Months and older
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Glioblastoma Multiforme, Anaplastic Astrocytoma
Interventions: Not listed
Lead sponsor: Guoqiang Yu; Other
Eligibility: 18 Years to 90 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Coronary Artery Disease
Interventions: HF-OCT Imaging with the Vis-Rx Micro-Imaging Catheter; Device
Lead sponsor: Gentuity, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 257 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Tampa, Florida • Lexington, Kentucky • Lebanon, New Hampshire

Conditions: Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple Sclerosis, Huntington Disease, Lewy Body Dementia, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis (ALS), APOE-4 Positive, Traumatic Brain Injury, Concussion, Post-Traumatic Stress Disorder, Down Syndrome, Neuro-Degenerative Disease, Normal Cognition
Interventions: Retinal and Choroidal Imaging; Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Genitourinary Anatomy
Interventions: Not listed
Lead sponsor: Lambda Surgical, Inc; Industry
Eligibility: 22 Years and older · Male only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Skin Cancer
Interventions: OIR Imaging; Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: Not listed
Enrollment: 490 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Brain Neoplasm, Malignant Glioma
Interventions: Cetuximab, Cetuximab-IRDye 800CW, Tumor resection; Biological · Drug · Procedure
Lead sponsor: Eben Rosenthal; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Coronary Artery Disease (CAD)
Interventions: Optical Coherence Tomography (OCT), Intravascular Ultrasound (IVUS); Procedure
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer
Interventions: Diffuse Optical Spectroscopy Imaging (DOSI) - Neoadjuvant Chemo (NAC) Cohort, Diffuse Optical Spectroscopy Imaging (DOSI) - Non-NAC Cohort; Device
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cancer, Chemotherapy, Squamous Cell Carcinoma (SCC)
Interventions: Panitumumab-IRDye800; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older · Female only
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Retinal Degeneration, Age-Related Macular Degeneration, Retinitis Pigmentosa, Hydroxychloroquine Retinopathy, Usher Syndromes, Late-Onset Retinal Degeneration, Cone Dystrophy, Cone Rod Dystrophy, Rod Cone Dystrophy, Rod Dystrophy
Interventions: Adaptive optics imaging; Device
Lead sponsor: Food and Drug Administration (FDA); Federal
Eligibility: 21 Years and older
Enrollment: 100 participants
Timeline: 2021 – 2028
U.S. locations: 2
States / cities: Bethesda, Maryland • Silver Spring, Maryland

Conditions: Lung Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions: Near-Infrared Fluorescence Imaging, Panitumumab-IRDye800, Pharmacokinetic Study, Therapeutic Conventional Surgery; Procedure · Drug · Other
Lead sponsor: Stanford University; Other
Eligibility: 19 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Search by objective public record fields.

Optical Frequency Domain Imaging (OFDI) Assessment in Radiofrequency Ablation

A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

Imaging the Duodenum Using an Optical Frequency Domain Imaging OFDI Capsule

Predicting Pathological Response Within the 1st Week of Chemotherapy Using Diffuse Optical Spectroscopic Imaging

Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes

Optical Coherence Tomography of the Gastrointestinal Tract

Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)

Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults

Optical Coherence Tomography Guided C&D

Optical Frequency Domain Imaging for Assessing Colonic Polyps

Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)

Imaging Retinal Vasculature in Infant Eyes

Long-Working Distance OCT for Children

Loupe-Based Intraoperative Fluorescence Imaging

Vis-Rx Post-Market Evaluation

Retinal Imaging in Neurodegenerative Disease

Observational Study of the LambdaGuide System for Measurement of Observable Genitourinary Anatomy During Cystoscopic Procedures in Men

Melanoma Detection by Oblique-Incidence Optical Spectroscopy

Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery

Optical Coherence Tomography (OCT) Intravascular Ultrasound (IVUS) Dual Imaging

Monitoring Neoadjuvant Chemotherapy Response in Breast Cancer Patients Using Diffuse Optical Spectroscopic Imaging

A Project Assessing the Safety and Feasibility of Using Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Ovarian Cancer During Surgical Procedures

Adaptive Optics Imaging of Outer Retinal Diseases

Panitumumab-IRDye800 in Detecting Cancer in Participants With Lung Cancer During Surgery