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ClinicalTrials.gov public records Last synced Oct 1, 2026, 1:32 PM EDT

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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Oropharyngeal Dysphagia Clear all
Completed Phase 2 Interventional Results available

Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer

NCT01032928
View directory record Official record
Conditions
Oropharyngeal Dysphagia, Oropharyngeal Cancer
Interventions
Respiratory-Swallow Phase training
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 1, 2015 · Synced Oct 1, 2026, 1:32 PM EDT
Terminated No phase listed Observational

Oropharyngeal Function After Radiotherapy With IMRT

NCT00506324
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 79 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 14, 2015 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Rehabilitation Manometry Study

NCT04130867
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
pHRM, VFSS
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional

Training Swallowing Initiation During Expiration

NCT05278039
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Squamous Cell Carcinoma
Interventions
Respiratory-Swallow Phase Training, Swallow Practice
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Terminated Phase 2 Interventional Results available

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

NCT00503776
View directory record Official record
Conditions
Dysphagia, Head and Neck Cancer, Mucositis, Xerostomia
Interventions
exercise intervention, amifostine trihydrate, therapeutic dietary intervention
Behavioral · Drug · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
21 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of an Oropharyngeal Aerosolized pH Probe for Diagnosing Laryngopharyngeal Reflux (LPR)

NCT00321503
View directory record Official record
Conditions
Laryngopharyngeal Reflux
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Acupuncture Treatment for Dysphagia

NCT00797732
View directory record Official record
Conditions
Carcinomas, Squamous Cell, Dysphagia
Interventions
Acupuncture
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Oct 1, 2026, 1:32 PM EDT
Enrolling by invitation Not applicable Interventional

WeCareToFeedDysphagia to Reduce Care-partner Burden Full-scale RCT

NCT07250113
View directory record Official record
Conditions
Caregiver Burden, Alzheimer's Disease, Dementia, Oropharyngeal Dysphagia, Older Adults
Interventions
WeCareToFeedDysphagia web tool
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Recruiting Not applicable Interventional

Tongue-strengthening Exercises in People With ALS.

NCT07295990
View directory record Official record
Conditions
ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis
Interventions
Isometric Lingual Strength Exercises
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional Results available

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

NCT03377270
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia
Interventions
Respiratory Swallow Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational

Ultrasound and Videofluoroscopy for Diagnosing Swallowing Disorders

NCT00001220
View directory record Official record
Conditions
Deglutition Disorder, Motor Neuron Disease
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1987 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational

Oral and Swallowing Function in Older Adults

NCT06368830
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
3-ounce water swallow test, Kayser-Jones Brief Oral Health Status Examination (BOHSE), Tongue pressure, Test of Masticating and Swallowing Solids (TOMASS), Respiratory function tests
Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Not listed No phase listed Observational

Pulmonary Health in Children With Down Syndrome

NCT04398862
View directory record Official record
Conditions
Down Syndrome, Dysphagia, Oropharyngeal
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
3 Years to 18 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 26, 2024 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational Results available

The Passy Muir Swallowing Self Training Device

NCT01765673
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Vibrotactile stimulation
Device
Lead sponsor
James Madison University
Other
Eligibility
20 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Harrisonburg, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 1, 2026, 1:32 PM EDT
Terminated Not applicable Interventional Results available

Pilot Study to Improve Therapeutic Outcomes for Dysphagia After Radiation Therapy

NCT02564887
View directory record Official record
Conditions
Dysphagia, Oral Pharyngeal Cancer
Interventions
Iowa Oral Performance Instrument
Device
Lead sponsor
Jonas Johnson
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Oct 1, 2026, 1:32 PM EDT
Active, not recruiting Phase 2 Interventional

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

NCT03224000
View directory record Official record
Conditions
Malignant Neoplasms of Lip Oral Cavity and Pharynx, Oropharyngeal Cancer
Interventions
Modified Barium Swallow (MBS), Swallowing Questionnaire, Symptom Questionnaire, Video-Strobe Procedure, MRI Guided Intensity Modulated Radiotherapy (IMRT) Planning, Standard-of-Care Intensity Modulated Radiotherapy (IMRT) Planning, Intensity Modulated Radiotherapy (IMRT)
Procedure · Behavioral · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional

Silk Protein Microparticle-based Filler for Injection Augmentation

NCT03790956
View directory record Official record
Conditions
Vocal Cord Paralysis Unilateral, Dysphonia, Dysphagia, Oropharyngeal
Interventions
Silk Microparticle Filler Injection
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional

Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia

NCT03368079
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Negative Pressure Suction Catheter
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Reference Values for Videofluoroscopic Measures of Swallowing

NCT05497219
View directory record Official record
Conditions
Dysphagia, Oropharyngeal
Interventions
Videofluoroscopic Swallowing Study (VF)
Diagnostic Test
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
3
States / cities
Gainesville, Florida • Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Recruiting Not applicable Interventional

K01 Impacts of Lingual Endurance Exercise

NCT06072924
View directory record Official record
Conditions
Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke, Stroke
Interventions
Isotonic Endurance Exercise, Sham Exercise
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Recruiting Not applicable Interventional

Investigation of a Free Water Protocol

NCT06309602
View directory record Official record
Conditions
Oropharyngeal Dysphagia
Interventions
Free Water Protocol, Control / Standard Care
Other
Lead sponsor
Poudre Valley Health System
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Loveland, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 1, 2026, 1:32 PM EDT
Completed Not applicable Interventional Results available

Reducing Burden in Care Partners of Community-Dwelling Persons With Dementia and Oropharyngeal Dysphagia

NCT06557863
View directory record Official record
Conditions
Caregiver Burden, Alzheimer Disease, Dementia, Oropharyngeal Dysphagia
Interventions
WeCareToFeedDysphagia web tool
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Recruiting Phase 2 Interventional

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

NCT06638944
View directory record Official record
Conditions
Dysphagia, Stroke, Parkinson Disease
Interventions
In-person sEMG-biofeedback, Remote sEMG-biofeedback, Standard-of-care treatment
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
50 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Champaign, Illinois • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 1, 2026, 1:32 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) Reflux

NCT01091805
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Not listed
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 1, 2026, 1:32 PM EDT