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ClinicalTrials.gov public records Last synced Jul 24, 2026, 5:14 PM EDT

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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Conditions
Malocclusion
Interventions
Orthodontic Treatment, OrthoPulse™
Other · Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Malocclusion
Interventions
Fixed Appliance Orthodontic Treatment, OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy

NCT02119455
Conditions
Tooth Movement
Interventions
Vibration Device
Device
Lead sponsor
UConn Health
Other
Eligibility
15 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Orthodontic Appliance Complication
Interventions
Corresponding treatment order in the prescription with Align Technology, Superimposition of final and initial positions of lateral incisors: Predicted model, Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners, Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x4mm aligners, Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x5mm aligners
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Richmond, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant

NCT03306433
Conditions
Dental Caries
Interventions
UDMA-K18 smooth surface sealant
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 89 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Aurora, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Use of Orthopulse Photobiomodulation

NCT05650359
Conditions
Orthodontics
Interventions
OrthoPulse, No intervention
Device · Other
Lead sponsor
Biolux Technology GmbH
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chandler, Arizona
Completed Early Phase 1 Interventional Accepts healthy volunteers

Prevention of Enamel Demineralization Using CPP-ACP-NaF Varnish

NCT04002232
Conditions
Demineralization
Interventions
CPP-ACP-NaF varnish
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Hiroko Nagaoka
Other
Eligibility
10 Years to 70 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Obesity & Overweight, Orthodontic Treatment
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 18 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, New York
Conditions
Malocclusion
Interventions
Motion View, Conventional Orthodontic Treatment
Procedure
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
Up to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
Interventions
Active TENS Device, Intervention 2: Placebo/Sham Device
Device
Lead sponsor
University of the Pacific
Other
Eligibility
12 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California
Conditions
Orthodontic Appliances
Interventions
Xylitol Gum
Drug
Lead sponsor
West Virginia University
Other
Eligibility
Up to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Morgantown, West Virginia
Conditions
Malocclusion, Misaligned Teeth
Interventions
Clear Aligners with Dental Monitoring, Clear Aligners
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
12 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
4
States / cities
Antioch, Illinois • Chicago, Illinois • Grayslake, Illinois + 1 more