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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Orthopaedic Injuries Clear all
Completed Not applicable Interventional

Treatment of Post-Traumatic Stress Disorder (PTSD) and Chronic Pain After Traumatic Orthopedic Injury

NCT00957164
View directory record Official record
Conditions
Chronic Pain, Post-traumatic Stress Disorder
Interventions
Brief Prolonged Exposure Protocol, Chronic Pain Management Treatment, Self-Care
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
4
States / cities
Arlington, Texas • Fort Sam Houston, Texas • Lackland Air Force Base, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Sep 23, 2026, 3:59 AM EDT
Recruiting Phase 4 Interventional

Single-dose Intravenous Iron Therapy for Anemia After Orthopaedic Trauma

NCT05292001
View directory record Official record
Conditions
Acute Blood Loss Anemia, Fracture
Interventions
Iron-Dextran Complex Injection [InFed], Saline Placebo
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Phase 2 Interventional Results available

Study to Assess Safety and Clinical Activity of Local MBN-101 in Treatment of Infected Bone Sites

NCT02436876
View directory record Official record
Conditions
Bacterial Infection
Interventions
MBN-101, Placebo
Drug · Other
Lead sponsor
Microbion Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
6
States / cities
San Francisco, California • Baltimore, Maryland • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Sep 23, 2026, 3:59 AM EDT
Withdrawn Not applicable Interventional

Radiation Exposure Using Laser Guided Fluoroscopy in Various Orthopaedic Procedures

NCT00972647
View directory record Official record
Conditions
Fractures
Interventions
Laser beam guidance
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

Improving Patient Satisfaction Improving Patient Satisfaction

NCT01263639
View directory record Official record
Conditions
Satisfaction, Trauma
Interventions
Orthopaedic Attending Biosketch Card, Standard of care - No biosketch card
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 27, 2014 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

Antibiotic Prophylaxis in Orthopaedic Traumatology

NCT00610987
View directory record Official record
Conditions
Fractures, Closed, Wounds and Injuries
Interventions
cefazolin, Placebo
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2015 · Synced Sep 23, 2026, 3:59 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

A Multi-Center Protocol for Obtaining and Storing Human Samples for Immediate or Future Microbial, Immune, or Host Microbe Scientific Study

NCT00765141
View directory record Official record
Conditions
Infection
Interventions
Not listed
Lead sponsor
Southwest Regional Wound Care Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 25, 2015 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Pain and Narcotic Usage After Orthopaedic Surgery

NCT03991546
View directory record Official record
Conditions
Fractures, Closed, Pain, Postoperative, Pain Catastrophizing, Pain, Acute, Analgesia, Opioid Use, Acceptance and Commitment Therapy, Orthopedics, Analgesics, Opioid, Text Messaging
Interventions
Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot
Behavioral
Lead sponsor
Christopher Anthony
Other
Eligibility
18 Years to 100 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Phase 4 Interventional Results available

Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients

NCT02152163
View directory record Official record
Conditions
Pain
Interventions
IV Ibuprofen, placebo
Drug
Lead sponsor
Delray Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Delray Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Suture Closure Trial

NCT05261425
View directory record Official record
Conditions
Surgical Wound, Upper Extremity Injury
Interventions
Monocryl buried, Nylon (FDA Approved) not buried
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 23, 2026, 3:59 AM EDT
Completed No phase listed Observational

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714
View directory record Official record
Conditions
Orthopaedic Trauma
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,065 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
44
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 37 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 23, 2026, 3:59 AM EDT
Recruiting Phase 4 Interventional

Identifying and Treating Depression in the Orthopaedic Trauma Population

NCT05976347
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine 20 MG, Duloxetine 30 MG, Observation
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 23, 2026, 3:59 AM EDT
Not listed Phase 3 Interventional

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

NCT05000281
View directory record Official record
Conditions
Tibia Fracture
Interventions
Ibuprofen
Drug
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Sep 23, 2026, 3:59 AM EDT
Completed No phase listed Observational Results available

ICG Fluorescence Imaging in Trauma Patients

NCT04245111
View directory record Official record
Conditions
Trauma Injury
Interventions
Immunofluorescence Imaging
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional

Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization

NCT02779244
View directory record Official record
Conditions
Ankle Fracture
Interventions
Early Weight bearing + Cam Boot, Non-Weight Bearing + Cam Boot
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Activation in Orthopaedic Trauma Patients: A Pilot Study

NCT04426981
View directory record Official record
Conditions
Fractures, Bone
Interventions
Behavioral Activation
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced Sep 23, 2026, 3:59 AM EDT
Completed Not applicable Interventional Results available

Orthopaedic Surgical Wound Closure Comparison Study

NCT05251064
View directory record Official record
Conditions
Incision, Surgical
Interventions
Suture, Clozex, Zipline
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced Sep 23, 2026, 3:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery

NCT06429267
View directory record Official record
Conditions
Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction
Interventions
Bioabsorbable Screw, Metal/Titanium Screw
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
Up to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Sep 23, 2026, 3:59 AM EDT
Withdrawn Not applicable Interventional

Dialectical Behavioral Therapy in High Risk OrthopaedicTrauma Patients

NCT03776929
View directory record Official record
Conditions
Fracture, Surgery
Interventions
Dialectical Behavioral Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 23, 2026, 3:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparing Ketamine and Morphine in the Treatment of Acute Fracture Pain

NCT02430818
View directory record Official record
Conditions
Acute Pain, Fractures
Interventions
ketamine, morphine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Sep 23, 2026, 3:59 AM EDT
Terminated Phase 2 Interventional

Image Guided System for Orthopaedic Surgery

NCT00022802
View directory record Official record
Conditions
Orthopaedic Trauma, Hip Fracture
Interventions
Image-guided surgical system
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Sep 23, 2026, 3:59 AM EDT
Not listed Not applicable Interventional

A Patient Education Video Program for Post-Operative Recovery After Upper Extremity Surgery

NCT03366805
View directory record Official record
Conditions
Analgesics, Opioid, Orthopedic Surgery, Ambulatory Surgery, Education, Patient, Injuries and Wounds
Interventions
Pain Management Patient Education Video, Wound Care Patient Education Video
Behavioral
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Sep 23, 2026, 3:59 AM EDT
Withdrawn Phase 4 Interventional

Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population

NCT04464512
View directory record Official record
Conditions
Addiction Opiate, Chronic Pain, Fractures, Bone, Buprenorphine Dependence
Interventions
Sufentanil
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced Sep 23, 2026, 3:59 AM EDT
Suspended Phase 1Phase 2 Interventional

Vitamin D and Bone Homeostasis in Ortho Polytrauma Patients

NCT03066817
View directory record Official record
Conditions
Vitamin D Deficiency, Polytrauma, Orthopedic Disorder
Interventions
Ergocalciferol 8000 IU/ML Oral Liquid [DRISDOL], Propylene Glycol
Drug
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Sep 23, 2026, 3:59 AM EDT