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Showing 1–24 of 427 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Orthopedic Clear all
Completed No phase listed Observational

Patient Satisfaction Scales

NCT03686735
View directory record Official record
Conditions
All Orthopedic Disorders, New or Follow-up Patients
Interventions
5 anchors and numbers, 5 anchors and no numbers, Visual analog scale with 3 anchors and numbers, Visual analog scale with 3 anchors and no numbers
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
256 participants
Timeline
2018 – 2019
U.S. locations
6
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2019 · Synced Sep 2, 2026, 1:45 PM EDT
Recruiting Phase 3 Interventional

Opioid-Free Orthopaedics

NCT04659317
View directory record Official record
Conditions
Pain, Pain, Postoperative
Interventions
Oxycodone 5 mg Oral Tablet, Placebo oral tablet
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
3
States / cities
Atlanta, Georgia • Tucker, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions

NCT00596050
View directory record Official record
Conditions
Conscious Sedation Failure During Procedure
Interventions
ketamine and midazolam, etomidate, fentanyl, and lidocaine
Drug
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
5 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2017 · Synced Sep 2, 2026, 1:45 PM EDT
Recruiting Phase 4 Interventional

Post Operative Infusion Pump Pain Study

NCT07349810
View directory record Official record
Conditions
Post Operative Pain
Interventions
Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel), ambIT Infusion Pump
Drug · Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional

The Relationship Between Needle Position and Injection Pressure During Femoral Nerve Block

NCT02451813
View directory record Official record
Conditions
Orthopedic Disorders
Interventions
Apposition of needle bevel against femoral nerve
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 2, 2026, 1:45 PM EDT
Completed No phase listed Observational

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714
View directory record Official record
Conditions
Orthopaedic Trauma
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 80 Years
Enrollment
1,065 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
44
States / cities
Birmingham, Alabama • San Diego, California • San Francisco, California + 37 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional

Virtual Reality Instructional Design in Orthopedic Physical Therapy Education

NCT04754568
View directory record Official record
Conditions
Virtual Reality
Interventions
Virtual reality instructional design, Role-playing instructional design
Other
Lead sponsor
Shenandoah University
Other
Eligibility
22 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain in Acute Orthopedic Injuries

NCT05552430
View directory record Official record
Conditions
Injuries, Injury Arm, Injury;Sports, Injury, Knee, Injury Wrist, Injury, Ankle, Injury Foot, Injury, Hand, Injury Finger, Injury Leg
Interventions
RelieveVRx
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 2, 2026, 1:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Retrieval and Analysis of Orthopedic Implants at Revision Arthroplasty Surgery

NCT01425021
View directory record Official record
Conditions
Total Joint Revisions
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 85 Years
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Sep 2, 2026, 1:45 PM EDT
Recruiting Phase 4 Interventional

Identifying and Treating Depression in the Orthopaedic Trauma Population

NCT05976347
View directory record Official record
Conditions
Depression
Interventions
Fluoxetine 20 MG, Duloxetine 30 MG, Observation
Drug · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

Ventilation Strategy During General Anesthesia for Orthopedic Surgery: A Quality Improvement Project

NCT03657368
View directory record Official record
Conditions
Orthopedic Surgery, Ventilation
Interventions
Low tidal Volume, High tidal Volume, Low PEEP, High PEEP
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2,860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 2, 2026, 1:45 PM EDT
Completed No phase listed Observational

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries

NCT03422211
View directory record Official record
Conditions
Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use, Opioid Abuse, Uncomplicated, Opioids; Harmful Use, Analgesic Drug Dependence, Orthopedic Disorder
Interventions
Questionnaire
Other
Lead sponsor
St. Louis University
Other
Eligibility
10 Years to 100 Years
Enrollment
223 participants
Timeline
2017 – 2018
U.S. locations
3
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 2, 2026, 1:45 PM EDT
Completed No phase listed Observational

Pre and Post Orthopedic Surgery Sleep and Cardiac Testing (PROSPECT)

NCT00785070
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Memorial Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 8, 2009 · Synced Sep 2, 2026, 1:45 PM EDT
Withdrawn No phase listed Observational

Investigation of Systemic Metal Ion Concentration Following a Ceramic-on-metal Total Hip Arthroplasty

NCT00883805
View directory record Official record
Conditions
Hip Replacement, Hip Implant, Total Hip Arthroplasty, Orthopaedic Surgery
Interventions
Blood draw, X-Ray of Hip
Biological · Radiation
Lead sponsor
Northwell Health
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2015 · Synced Sep 2, 2026, 1:45 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks in Pediatric Orthopedic Patients

NCT02236130
View directory record Official record
Conditions
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Interventions
Regional block, General Anesthesia, Local Anesthetic Ropivacaine, Opioids Morphine, Oral pain medication Acetaminophen with Hydrocodone
Procedure · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 12, 2017 · Synced Sep 2, 2026, 1:45 PM EDT
Terminated No phase listed Observational

Anticipated Versus Actual Patient and Caregiver Burden Following Ambulatory Orthopedic Surgery

NCT02550886
View directory record Official record
Conditions
Stress, Psychological, Pain
Interventions
Survey
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Sep 2, 2026, 1:45 PM EDT
Active, not recruiting Not applicable Interventional

Suture Versus Staples for Wound Closure in Orthopaedic Trauma Surgery

NCT06586814
View directory record Official record
Conditions
Lower Extremity Fracture
Interventions
Suture, Staple
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 2, 2026, 1:45 PM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery

NCT06179004
View directory record Official record
Conditions
Distal Radius Fractures, Wrist Fractures
Interventions
Liposomal bupivacaine, Bupivacaine Hydrochloride
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 2, 2026, 1:45 PM EDT
Not listed Phase 4 Interventional

Deep Vein Thrombosis Prophylaxis Adherence: Enoxaparin vs Rivaroxaban

NCT04169269
View directory record Official record
Conditions
Deep Vein Thrombosis, Venous Thromboembolism
Interventions
Enoxaparin 40 milligram/0.4 milliliter Injectable Syringe 0.4 milliliters, Rivaroxaban 10 milligram Oral Tablet
Drug
Lead sponsor
Florida Orthopaedic Institute
Network
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 2, 2026, 1:45 PM EDT
Enrolling by invitation No phase listed Observational

A Clinical Registry of Orthobiologics Procedures

NCT03011398
View directory record Official record
Conditions
Orthopedic Disorder
Interventions
Orthobiologic Procedures
Procedure
Lead sponsor
Regenexx, LLC
Industry
Eligibility
Not listed
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2036
U.S. locations
30
States / cities
Phoenix, Arizona • Beverly Hills, California • Oceanside, California + 26 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2025 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain Management in Orthopaedic Patients

NCT04152447
View directory record Official record
Conditions
Pain, Musculoskeletal
Interventions
VR device
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 2, 2026, 1:45 PM EDT
Completed Not applicable Interventional Results available

A Study to Determine if Carbon Dioxide Lavage During Total Knee Surgery Reduces Intraoperative Embolic Events

NCT00736125
View directory record Official record
Conditions
Postoperative Complications, Memory Disorders
Interventions
pulsatile saline lavage, carbon dioxide lavage
Device
Lead sponsor
Kinamed Incorporated
Industry
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 2, 2026, 1:45 PM EDT
Not listed No phase listed Observational

Serum Based Diagnosis of and Monitoring of Infection Recovery in Orthopedic Spine Implant Infections

NCT04897971
View directory record Official record
Conditions
Staphylococcus Aureus Infection, Surgical Site Infection, Orthopedic Procedures, Spine
Interventions
Medium enriched for newly synthesized antibodies in spine infection
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Sep 2, 2026, 1:45 PM EDT