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Showing 1–24 of 178 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Orthopedic Injury Clear all
Withdrawn Phase 4 Interventional

Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population

NCT04464512
View directory record Official record
Conditions
Addiction Opiate, Chronic Pain, Fractures, Bone, Buprenorphine Dependence
Interventions
Sufentanil
Drug
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial

NCT02025400
View directory record Official record
Conditions
Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear, Patellofemoral Pain
Interventions
eRehab, Formal Physical Therapy
Other
Lead sponsor
Charlotte Sports Medicine Institute, PA
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Prince Frederick, Maryland • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 31, 2013 · Synced Jun 10, 2026, 10:01 AM EDT
Completed No phase listed Observational

Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): Onsite Follow-up

NCT00478894
View directory record Official record
Conditions
Rupture of Anterior Cruciate Ligament, Osteoarthritis
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
14 Years to 55 Years
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2025
U.S. locations
4
States / cities
St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jun 10, 2026, 10:01 AM EDT
Withdrawn Not applicable Interventional

Spine and Tumor Screening and Supplementation

NCT03660540
View directory record Official record
Conditions
Spinal Injuries, Sarcoma, Nutritional Deficiency
Interventions
Juven
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional

The Impact of Telemedicine on Orthopaedic Trauma Patients With Closed Fractures

NCT01991782
View directory record Official record
Conditions
Telemedicine, Fracture
Interventions
Telemedicine
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 29, 2014 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Phase 3 Interventional Results available

Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury

NCT01270659
View directory record Official record
Conditions
Pain
Interventions
Fentanyl, oxycodone/acetaminophen
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Jun 10, 2026, 10:01 AM EDT
Completed No phase listed Observational

Evaluating Bactisure Wound Lavage in Orthopedic Wounds

NCT03192124
View directory record Official record
Conditions
Infection of Total Knee Joint Prosthesis
Interventions
Bactisure
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
5
States / cities
Los Angeles, California • Lexington, Kentucky • Louisville, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Jun 10, 2026, 10:01 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries

NCT04793022
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury, Anesthesia
Interventions
TIVA with Propofol, Inhaled Anesthesia
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Jun 10, 2026, 10:01 AM EDT
Terminated Phase 2 Interventional

Image Guided System for Orthopaedic Surgery

NCT00022802
View directory record Official record
Conditions
Orthopaedic Trauma, Hip Fracture
Interventions
Image-guided surgical system
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Jun 10, 2026, 10:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Injection Pressure & Adductor Canal Block

NCT02563990
View directory record Official record
Conditions
Orthopedic Disorders, Injury of Anterior Cruciate Ligament
Interventions
High Pressure Injection, Low Pressure Injection
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional

The Impact of a mHealth Application on Outpatient Physical Therapy HEP Adherence and Outcomes: A RCT

NCT03035682
View directory record Official record
Conditions
Orthopedic Disorder, Musculoskeletal Injury
Interventions
Augmented Media Group, Traditional Group
Other
Lead sponsor
Aultman Health Foundation
Other
Eligibility
18 Years to 100 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional

Effects of Thoracic Orthopedic Manual Therapy and Biopsychosocial Variables on Signs of Shoulder Impingement

NCT01743833
View directory record Official record
Conditions
Shoulder Impingement
Interventions
Thoracic High Velocity, Low Amplitude Thrust Maneuver (HVLATM), Scapular High Velocity, Low Amplitude Thrust Maneuver
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 69 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Jun 10, 2026, 10:01 AM EDT
Not listed Not applicable Interventional

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

NCT02090140
View directory record Official record
Conditions
Degenerative Lesion of Articular Cartilage of Knee
Interventions
ADSC Application, Microfracture
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 50 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
3
States / cities
Redwood City, California • Santa Monica, California • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jun 10, 2026, 10:01 AM EDT
Completed No phase listed Observational

Socio-Economic Survey in Uganda

NCT01971697
View directory record Official record
Conditions
Orthopaedic Injury
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2015 · Synced Jun 10, 2026, 10:01 AM EDT
Recruiting Not applicable Interventional

MAPT Protocol: Fixation Versus Arthroplasty Surgical Treatments for Early Recovery After HIP Fracture (FASTER-HIP)

NCT07244211
View directory record Official record
Conditions
Femoral Neck Fractures
Interventions
Hip arthroplasty, Internal fixation
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
11
States / cities
Irvine, California • Los Angeles, California • Bloomington, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 10, 2026, 10:01 AM EDT
Completed No phase listed Observational Results available

ICG 24h Prior to Operative Treatment of Orthopaedic Infection

NCT04927637
View directory record Official record
Conditions
Trauma Injury, Bone Infection
Interventions
imaging 24 hours following intravenous administration of ICG
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Jun 10, 2026, 10:01 AM EDT
Terminated Not applicable Interventional Results available

Orthopedic Study of the Aircast StabilAir Wrist Fracture Brace

NCT00587795
View directory record Official record
Conditions
Radius Fractures
Interventions
StabilAir Wrist Brace, Placement of sugar tong splint or plaster cast
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Jun 10, 2026, 10:01 AM EDT
Terminated No phase listed Observational

Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion

NCT00441779
View directory record Official record
Conditions
Chimerism, Blood Transfusion, Wounds and Injuries
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
8 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional

Mindfulness Intervention in Orthopedic Trauma Patients

NCT05634278
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Preoperative mindfulness, Postoperative mindfulness, Mind wandering
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 16, 2025 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Phase 2 Interventional Results available

Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period

NCT00586196
View directory record Official record
Conditions
Delirium
Interventions
donepezil, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
70 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Jun 10, 2026, 10:01 AM EDT
Recruiting Not applicable Interventional

Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation

NCT06407427
View directory record Official record
Conditions
Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
Interventions
App for in-bed conditioning exercises, Usual care
Device · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional Results available

Virtual Reality for Pain in Acute Orthopedic Injuries

NCT05552430
View directory record Official record
Conditions
Injuries, Injury Arm, Injury;Sports, Injury, Knee, Injury Wrist, Injury, Ankle, Injury Foot, Injury, Hand, Injury Finger, Injury Leg
Interventions
RelieveVRx
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jun 10, 2026, 10:01 AM EDT
Completed Not applicable Interventional

Suture Closure Trial

NCT05261425
View directory record Official record
Conditions
Surgical Wound, Upper Extremity Injury
Interventions
Monocryl buried, Nylon (FDA Approved) not buried
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jun 10, 2026, 10:01 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Maxx Orthopedics' PCK Revision TKA Study of Component Survivorship

NCT03312088
View directory record Official record
Conditions
Aseptic Loosening, Infection, Bone Loss, MCL - Medial Collateral Ligament Rupture of the Knee, Periprosthetic Fractures
Interventions
Freedom Knee PCK Components
Device
Lead sponsor
Maxx Orthopedics Inc
Industry
Eligibility
40 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Jun 10, 2026, 10:01 AM EDT