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Showing 1–24 of 125 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Vaginal Orthosis Use After Vaginal Reconstructive Surgery

NCT05812859
Conditions
Pelvic Organ Prolapse
Interventions
Vaginal Orthosis (COSM Medical)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Active, not recruiting Not applicable Interventional

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041
Conditions
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Interventions
Casting, Bracing
Procedure · Device
Lead sponsor
University of Iowa
Other
Eligibility
12 Months to 36 Months
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
24
States / cities
Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more
Conditions
Foot Injury
Interventions
Modular Carbon Fiber Custom Dynamic Orthosis (CDO), Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
San Diego, California • Iowa City, Iowa • Minneapolis, Minnesota + 2 more
Conditions
Stroke, Brachial Plexus Injury, Spinal Cord Injuries, Neurological Disease
Interventions
Myoelectric Elbow-Wrist-Hand Orthosis
Device
Lead sponsor
Myomo
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • Chardon, Ohio • Edmonds, Washington
Conditions
Cerebral Palsy
Interventions
Upper Extremity Orthotic, Occupational Therapy
Device · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
4 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Newark, New Jersey • Union, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers Results available

Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty

NCT05307510
Conditions
Thumb Osteoarthritis
Interventions
Prefabricated splint, Custom Orthosis
Device
Lead sponsor
University of Toledo
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toledo, Ohio
Conditions
Lower Extremity Injuries
Interventions
Visual Feedback
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Everett, Washington
Conditions
Stroke, Hemiparesis
Interventions
MyHand Device
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Traumatic Lower Limb Injury
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
SCI - Spinal Cord Injury
Interventions
MyoMo, Myo-SB, Control
Device · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
West Orange, New Jersey
Conditions
Gait, Hemiplegic
Interventions
Ankle Orthotic
Device
Lead sponsor
University of Delaware
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Cerebrovascular Accidents
Interventions
Myoelectric Elbow-Wrist-Hand orthosis
Device
Lead sponsor
Myomo
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Chardon, Ohio
Conditions
Posterior Tibial Tendon Dysfunction
Interventions
Arizona
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Congenital Talipes Equinovarus
Interventions
Ankle Foot Orthosis (AFO)
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
Up to 12 Months
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Software Generated Customized Foot Orthoses

NCT05462912
Conditions
Arthropathy of Ankle or Foot
Interventions
custom foot orthotic
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Conditions
Medial Compartment Knee Osteoarthritis
Interventions
Medial joint distraction brace
Device
Lead sponsor
Icarus Medical Innovations
Industry
Eligibility
30 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Diabetes Mellitus, Peripheral Neuropathy, Orthotic Device
Interventions
Carbon Fiber Off Loading Orthosis (CFO)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
21 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Ankle Osteoarthritis, Healthy Ankles
Interventions
Rocker bottom shoe, Ankle foot orthosis, Standard walking shoe
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
Interventions
Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more
Completed Not applicable Interventional Results available

MyHand: An Active Hand Orthosis for Stroke Patients

NCT03767894
Conditions
Stroke
Interventions
EMG Band, Shoulder harness
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Plantar Fasciitis
Interventions
Custom PFO, Faux orthosis
Device · Other
Lead sponsor
University of Puget Sound
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tacoma, Washington
Completed No phase listed Observational Accepts healthy volunteers

Gait Adaptations to Passive Dynamic Ankle-Foot Orthosis Use

NCT00115401
Conditions
Joint Instability
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Walking Aided by a Leg Brace in Stroke Subjects
Interventions
ADR™ brace resistance, Conventional brace resistance (using hard stops)
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Terminated Not applicable Interventional Results available

Effectiveness of Ankle Foot Orthoses on Gait in Multiple Sclerosis

NCT01796860
Conditions
Multiple Sclerosis
Interventions
AFO
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas