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ClinicalTrials.gov public records Last synced Sep 9, 2026, 3:57 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Foot Injury
Interventions
Modular Carbon Fiber Custom Dynamic Orthosis (CDO), Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
San Diego, California • Iowa City, Iowa • Minneapolis, Minnesota + 2 more
Conditions
Stroke
Interventions
Electrical stimulation-dynamic hand orthosis
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
20 Years to 85 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Brachial Plexus Injury
Interventions
Exoskeleton glove
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 69 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Conditions
Limb Injury
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
San Diego, California • Bethesda, Maryland • Rochester, Minnesota + 1 more
Conditions
Lower Extremity Injuries
Interventions
Visual Feedback
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Everett, Washington
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis

NCT02902211
Conditions
Peripheral Artery Disease
Interventions
Ankle foot orthosis, Control/standard of care
Device · Other
Lead sponsor
University of Nebraska
Other
Eligibility
40 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
Omaha, Nebraska
Conditions
Traumatic Brain Injury, Stroke
Interventions
MyoPro Motion-G, Motor Learning-Based Therapy
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Withdrawn No phase listed Observational Accepts healthy volunteers

SCANLOAD: The Effect of Limb Loading on Lower Limb Geometry

NCT04600102
Conditions
Foot Injuries and Disorders
Interventions
Structure Sensor
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Stroke
Interventions
Dynamic ankle-foot orthosis
Device
Lead sponsor
University of Delaware
Other
Eligibility
21 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Conditions
Crouch Gait, Cerebral Palsy (CP)
Interventions
RKO-assisted walking in individuals with CP
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
8 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Results available

WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients

NCT01087957
Conditions
Stroke
Interventions
WalkAide, Ankle-Foot Orthosis (AFO)
Device · Other
Lead sponsor
Innovative Neurotronics
Industry
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
29
States / cities
Loma Linda, California • Los Angeles, California • Pomona, California + 25 more
Conditions
Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes, Arthritis, Cancer, Peripheral Arterial Disease, Parkinson's Disease, End Stage Renal Failure on Dialysis
Interventions
MBB AFO, Control
Device · Other
Lead sponsor
Bijan Najafi, PhD
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

Ankle Foot Orthosis Comparative Effect

NCT03901053
Conditions
Foot Injuries and Disorders
Interventions
Reaktiv AFO, PhatBrace AFO
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
Conditions
Cerebral Palsy
Interventions
Upper Extremity Orthotic, Occupational Therapy
Device · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
4 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Newark, New Jersey • Union, New Jersey
Conditions
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Conditions
Stroke, Hemiparesis
Interventions
MyHand Device
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Active, not recruiting Not applicable Interventional

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041
Conditions
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Interventions
Casting, Bracing
Procedure · Device
Lead sponsor
University of Iowa
Other
Eligibility
12 Months to 36 Months
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
24
States / cities
Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more
Conditions
Posterior Tibial Tendon Dysfunction
Interventions
Arizona
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NYRC Brace Scoliosis Monitor
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 17 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Lower-limb Orthoses, Frailty/Sarcopenia, Chronic Overuse Musculoskeletal Injuries
Interventions
Modular powered orthosis
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Cerebrovascular Accidents
Interventions
Myoelectric Elbow-Wrist-Hand orthosis
Device
Lead sponsor
Myomo
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Chardon, Ohio