- Conditions
- Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 760 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2035
- U.S. locations
- 16
- States / cities
- Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 241–264
of 1,212
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Knee Osteoarthritis
- Interventions
- Percutaneous Pulsed Radiofrequency, Physical Therapy
- Device · Procedure
- Lead sponsor
- VA Long Beach Healthcare System
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2014
- U.S. locations
- 1
- States / cities
- Long Beach, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- PENNSAID Gel, Vehicle
- Drug
- Lead sponsor
- Mallinckrodt
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 260 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 26
- States / cities
- Tucson, Arizona • Sacramento, California • Clearwater, Florida + 22 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Gait Retraining
- Behavioral
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Knee Injuries, Knee Osteoarthritis, Patellofemoral Syndrome
- Interventions
- Limber Digital Application, Physical therapy Therapy
- Device · Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Osteoarthritis, Knee, Knee Pain Chronic
- Interventions
- Progressive Walking with Gait Retraining, Progressive Walking Program
- Behavioral
- Lead sponsor
- Northeastern University
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006 10 mg, FX006 40 mg, TCA IR 40 mg
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 3
- States / cities
- Paducah, Kentucky • Duncansville, Pennsylvania • Dallas, Texas
- Conditions
- Osteoarthritis of the Knees
- Interventions
- CX-011
- Drug
- Lead sponsor
- CarthroniX, Inc.
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Interventions
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Drug
- Lead sponsor
- F. Johannes Plate
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis Knee Pain
- Interventions
- Placebo, LY545694 49 mg, LY545694 105 mg
- Drug
- Lead sponsor
- Eli Lilly and Company
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 5
- States / cities
- Spring Valley, California • DeLand, Florida • South Miami, Florida + 2 more
- Conditions
- Osteoarthritis
- Interventions
- flavocoxid, Naproxen
- Dietary Supplement · Drug
- Lead sponsor
- Primus Pharmaceuticals
- Industry
- Eligibility
- 30 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Melbourne, Florida
- Conditions
- Osteoarthritis of the Knee, Pain
- Interventions
- REGN5069, Matching Placebo
- Drug
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 259 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 4
- States / cities
- DeLand, Florida • Jupiter, Florida • Miami, Florida + 1 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Amniotic Suspension Allograft, Placebo
- Biological · Drug
- Lead sponsor
- Organogenesis
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 594 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 41
- States / cities
- Birmingham, Alabama • Tempe, Arizona • La Mesa, California + 34 more
- Conditions
- Osteoarthritis
- Interventions
- Walking exercise, Cycling Exercise
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 306 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2007
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Knee Osteoarthritis
- Interventions
- Platelet Rich Plasma Injection
- Biological
- Lead sponsor
- University of Toledo Health Science Campus
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Toledo, Ohio
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
- Interventions
- Exercise for Knee Osteoarthritis, Compact seated elliptical exercise machine- Cubii JR-1
- Other · Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 50 Years to 75 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Lorecivivint
- Drug
- Lead sponsor
- Biosplice Therapeutics, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 72 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 4
- States / cities
- Tucson, Arizona • Winter Park, Florida • Oak Brook, Illinois + 1 more
- Conditions
- Knee Osteoarthritis
- Interventions
- Duloxetine, Celecoxib, Placebo
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 41 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Knee
- Interventions
- sc-rAAV2.5IL-1Ra
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Osteoarthritis
- Interventions
- nSTRIDE APS, Saline
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 332 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 27
- States / cities
- Birmingham, Alabama • Guntersville, Alabama • Tucson, Arizona + 24 more
- Conditions
- Osteoarthritis
- Interventions
- Gait Training; Altered Foot Progression Angle, Gait Training; Consistent Foot Progression Angle
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 2
- States / cities
- Palo Alto, California • Stanford, California
- Conditions
- Osteoarthritis of the Knee
- Interventions
- Aquamin F, Placebo (maltodextran)
- Drug
- Lead sponsor
- Marigot Ltd.
- Industry
- Eligibility
- 35 Years to 75 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Edina, Minnesota
- Conditions
- Knee Osteoarthritis
- Interventions
- Lavage with Platelet Poor Plasma (PPP)
- Biological
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 35 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- Osteoarthritis
- Interventions
- Naproxcinod 375 mg bid, Naproxcinod 750 mg bid, Naproxen 500 mg bid, placebo
- Drug
- Lead sponsor
- NicOx
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 1,020 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2007
- U.S. locations
- 73
- States / cities
- Chandler, Arizona • Tempe, Arizona • Tucson, Arizona + 70 more