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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Osteoarthritis, Shoulder Clear all
Completed Phase 4 Interventional Results available

Platelet-rich Plasma vs. Hyaluronic Acid for Glenohumeral Osteoarthritis

NCT02984228
View directory record Official record
Conditions
Osteoarthritis, Shoulder Pain
Interventions
PRP, Hyaluronic Acid, Ultrasound
Biological · Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 100 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2022 · Synced Jul 23, 2026, 10:56 AM EDT
Active, not recruiting No phase listed Observational

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

NCT01480440
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3-and 4-part Proximal Humeral Fractures, Avascular Necrosis, Gross Rotator Cuff Deficiency, Revision Total Shoulder Arthroplasty
Interventions
Trabecular Metal Reverse Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • Egg Harbor, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Terminated Phase 4 Interventional Results available

Osteoarthritis Shoulder Injection Study

NCT03586687
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Triamcinolone
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Jul 23, 2026, 10:56 AM EDT
Completed Phase 3 Interventional Results available

ORTHOVISC Shoulder Osteoarthritis Study

NCT00436969
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Orthovisc, Control
Device · Drug
Lead sponsor
DePuy Mitek
Industry
Eligibility
25 Years to 75 Years
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
13
States / cities
Encinitas, California • Fresno, California • Coral Gables, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2017 · Synced Jul 23, 2026, 10:56 AM EDT
Withdrawn Not applicable Interventional

Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

NCT06513559
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Anatomic total shoulder replacement, Reverse total shoulder replacement
Device
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 23, 2026, 10:56 AM EDT
Recruiting Phase 1 Interventional

The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis

NCT04929951
View directory record Official record
Conditions
Osteoarthritis Shoulder, Shoulder Pain
Interventions
Micro Fragmented Adipose Tissue, Corticosteroid injection
Biological
Lead sponsor
Stanford University
Other
Eligibility
25 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Jul 23, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Occupation-Based Intervention Compared With Therapeutic Exercise for Older Adults With Shoulder OA.

NCT04641546
View directory record Official record
Conditions
Osteoarthritis Shoulder
Interventions
Therapeutic Exercise, Occupation-Based Intervention
Procedure
Lead sponsor
Bay Path University
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 23, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional

Corticosteroid Injection Versus Nerve Block

NCT06735027
View directory record Official record
Conditions
Glenohumeral Arthritis, Rotator Cuff Arthropathy
Interventions
intraarticular corticosteroid injection (IACI), suprascapular nerve block (SSNB)
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Not listed Not applicable Interventional

Fixed Inclination Humeral Cut

NCT03922763
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Anatomical cut, Cutting guide
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Jul 23, 2026, 10:56 AM EDT
Terminated Phase 1 Interventional

Study of the Effect of Neck Treatment on Shoulder Impingement

NCT00764764
View directory record Official record
Conditions
Shoulder Impingement, Shoulder Pain, Rotator Cuff Tendinitis, Cervical Degenerative Joint Disease
Interventions
shoulder treatment, Shoulder AND cervical treatment
Procedure
Lead sponsor
CAMC Health System
Other
Eligibility
40 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 3, 2016 · Synced Jul 23, 2026, 10:56 AM EDT
Terminated No phase listed Observational

TITAN™ Reverse Shoulder System

NCT02204228
View directory record Official record
Conditions
Osteoarthritis of the Shoulder
Interventions
TITAN™ Reverse Shoulder System (TRS)
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
7
States / cities
Gainesville, Florida • Columbia, Maryland • Starkville, Mississippi + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Comprehensive Shoulder System Nano IDE

NCT01936259
View directory record Official record
Conditions
Joint Disease
Interventions
Mini Stem, Nano
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years to 90 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
12
States / cities
Scottsdale, Arizona • Fort Lauderdale, Florida • Fort Wayne, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2020 · Synced Jul 23, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

NCT04968405
View directory record Official record
Conditions
Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Rheumatoid Arthritis Shoulder
Interventions
Catalyst CSR Total Shoulder System
Device
Lead sponsor
Catalyst OrthoScience
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
Royal Oak, Michigan • Portland, Oregon • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Not listed No phase listed Observational

Treatment of Shoulder Osteoarthritis

NCT05657587
View directory record Official record
Conditions
Chronic Shoulder Pain
Interventions
SPRINT PNS
Device
Lead sponsor
Gramercy Pain Center
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Holmdel, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 26, 2023 · Synced Jul 23, 2026, 10:56 AM EDT
Not yet recruiting Phase 2 Interventional

Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis

NCT04448106
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Shoulder
Interventions
Celltex- AdMSCs
Biological
Lead sponsor
Celltex Therapeutics Corporation
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 23, 2026, 10:56 AM EDT
Active, not recruiting Phase 3 Interventional

ZILRETTA in Subjects With Shoulder Osteoarthritis

NCT06269705
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
ZILRETTA, Placebo
Drug · Other
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
50 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
32
States / cities
Vestavia Hills, Alabama • Surprise, Arizona • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Chronic Pain, Couples, & Physical Activity

NCT04077164
View directory record Official record
Conditions
Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Ankylosing Spondylitis, Rheumatoid Arthritis, Chronic Low-back Pain, Chronic Shoulder Pain
Interventions
No intervention, observational only.
Other
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jul 23, 2026, 10:56 AM EDT
Enrolling by invitation Not applicable Interventional

Pyrocarbon Hemiarthroplasty Versus Total Shoulder Arthroplasty for the Treatment of Glenohumeral Osteoarthritis

NCT07226388
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Hemiarthroplasty with pyrocarbon, Anatomic total shoulder arthroplasty
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Not listed Not applicable Interventional

Comparison Of A Novel Sling With A Traditional Abduction Sling After Shoulder Surgery

NCT05274737
View directory record Official record
Conditions
Rotator Cuff Tears, Osteo Arthritis Shoulders
Interventions
Novel sling, Traditional abduction sling
Device
Lead sponsor
Orthopedic Institute, Sioux Falls, SD
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Jul 23, 2026, 10:56 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Embo Registry; National Registry for Artery Embolization

NCT06477965
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder, Pain, Chronic, Tendonitis Elbow, Tendonitis Shoulder, Tendonitis;Achilles, Tenosynovitis
Interventions
Artery Embolization
Procedure
Lead sponsor
Vascular Solutions of North Carolina
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
2
States / cities
Cary, North Carolina • Winchester, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Jul 23, 2026, 10:56 AM EDT
Withdrawn Not applicable Interventional

Long Term Sidus PMCF

NCT04063943
View directory record Official record
Conditions
Osteoarthritis, Post-traumatic; Arthrosis
Interventions
Sidus Stem-Free Shoulder
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
4
States / cities
Louisville, Kentucky • Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced Jul 23, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Platelet Rich Plasma for Musculoskeletal Conditions

NCT07231471
View directory record Official record
Conditions
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder, Osteoarthritis Ankle, Elbow Osteoarthritis, Epicondylitis of the Elbow, Plantar Fasciitis of Both Feet, Tendinopathy
Interventions
Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
Biological · Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2035
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine for Pain Control After Total Shoulder Arthroplasty

NCT02762071
View directory record Official record
Conditions
Osteoarthritis, Arthropathy, Shoulder Pain, Closed Fracture Proximal Humerus, Four Part
Interventions
Liposomal bupivacaine, Interscalene Nerve Block
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 100 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Columbia, Maryland • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Jul 23, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional

Pectoralis Minor Release Versus Non-release in RSA

NCT06292169
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Tear Arthropathy, Advanced Glenohumeral Osteoarthritis
Interventions
Pectoralis Minor Release, RSA
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 23, 2026, 10:56 AM EDT