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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Osteoarthritis of the Hand Clear all
Completed Phase 1 Interventional

AP-011 Study to Evaluate the Safety of a Single Intra-articular Injection of Ampion™ for Arthritis of the Basal Thumb Joint

NCT02762760
View directory record Official record
Conditions
Osteoarthritis of the Hand
Interventions
AMPION™, Saline
Biological
Lead sponsor
Ampio Pharmaceuticals. Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 14, 2016 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 2 Interventional

Safety and Biologic Activity Study of Gevokizumab to Treat Erosive Osteoarthritis of the Hand

NCT01683396
View directory record Official record
Conditions
Osteoarthritis
Interventions
Placebo, gevokizumab
Drug
Lead sponsor
XOMA (US) LLC
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
27
States / cities
Huntsville, Alabama • Tucson, Arizona • Little Rock, Arkansas + 24 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Sep 27, 2026, 5:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis

NCT00685880
View directory record Official record
Conditions
Thumb Carpometacarpal Joint Osteoarthritis
Interventions
Prolotherapy (10% dextrose solution), Betamethasone
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2012 · Synced Sep 27, 2026, 5:14 AM EDT
Not listed Not applicable Interventional

Novel Splinting Technique Using 3D Models

NCT05351060
View directory record Official record
Conditions
Arthritis, Osteoarthritis Hand, Scleroderma, Systemic, Scleroderma, Diffuse, Rheumatoid Arthritis
Interventions
Custom Fabricated Splint
Other
Lead sponsor
Giovanna Fichera
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Troy, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 27, 2026, 5:14 AM EDT
Not listed Not applicable Interventional

Study of the Use of Laser Light to Treat Osteoarthritis of the Hand.

NCT00254111
View directory record Official record
Conditions
Osteoarthritis
Interventions
Ultra Probe Laser System
Device
Lead sponsor
TriTech Manufacturing
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
3
States / cities
Phoenix, Arizona • Long Beach, California • Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 14, 2005 · Synced Sep 27, 2026, 5:14 AM EDT
Recruiting Not applicable Interventional

Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb

NCT04828954
View directory record Official record
Conditions
Thumb Osteoarthritis
Interventions
Immobilization for 2-weeks postoperative, Immobilization for 6-weeks postoperative
Other
Lead sponsor
University of Chicago
Other
Eligibility
40 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 27, 2026, 5:14 AM EDT
Terminated Not applicable Interventional

Effect of Semiconductor Embedded Therapeutic Gloves for Hand Osteoarthritis

NCT06744855
View directory record Official record
Conditions
Hand Osteoarthritis, Osteoarthritis
Interventions
Non-invasive circulation gloves, Fabric gloves
Device
Lead sponsor
Altoona Center for Clinical Research
Network
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Duncansville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 27, 2026, 5:14 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Use of Allograft Adipose Matrix for Small Joint Arthritis of the Hand

NCT05747469
View directory record Official record
Conditions
Osteoarthritis Hand
Interventions
local anaesthetic injection, Human Adipose Allograft
Drug · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery

NCT06188221
View directory record Official record
Conditions
Hand Osteoarthritis, Trigger Finger, Carpal Tunnel Syndrome
Interventions
Lidocaine, Corticoids
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 2 Interventional

Safety and Biologic Activity Study of Gevokizumab to Treat Erosive Osteoarthritis of the Hand

NCT01882491
View directory record Official record
Conditions
Osteoarthritis
Interventions
Placebo, gevokizumab
Drug
Lead sponsor
XOMA (US) LLC
Industry
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
23
States / cities
Huntsville, Alabama • Tucson, Arizona • Roseville, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2014 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Diclofenac Sodium Gel in Hand Osteoarthritis

NCT00171665
View directory record Official record
Conditions
Osteoarthritis
Interventions
Diclofenac topical sodium gel 1%
Drug
Lead sponsor
Novartis
Industry
Eligibility
40 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
69
States / cities
Birmingham, Alabama • Calera, Alabama • Montgomery, Alabama + 60 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 2 Interventional Results available

A Study to Investigate the Efficacy and Safety of GSK3196165 in Inflammatory Hand Osteoarthritis

NCT02683785
View directory record Official record
Conditions
Osteoarthritis
Interventions
GSK3196165, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Miami, Florida • Duncansville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 4 Interventional

S-Asenosyl-L-Methionine vs Placebo for Osteoarthritis of the Hands

NCT05363020
View directory record Official record
Conditions
Osteoarthritis Hand
Interventions
S-Adenosyl-L-Methionine (Sam-E), Placebo
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 27, 2026, 5:14 AM EDT
Terminated Not applicable Interventional

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

NCT04692597
View directory record Official record
Conditions
Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management, Integrative Medicine
Interventions
Phoenix Thera-Lase System, SHAM Phoenix Thera-Lase System
Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 27, 2026, 5:14 AM EDT
Recruiting Phase 4 Interventional

Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis

NCT07217405
View directory record Official record
Conditions
Osteoarthritis Hand, Osteoarthritis Wrist
Interventions
Corticosteroid injection (CSI), Low-dose radiotherapy (LDRT)
Drug · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Effectiveness of Hand Exercises to Treat Symptoms of Hand Osteoarthritis

NCT00375947
View directory record Official record
Conditions
Osteoarthritis
Interventions
Hand Exercise, sham hand cream
Other
Lead sponsor
The Arthritis Research Institute of America
Other
Eligibility
50 Years and older
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Clearwater, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2007 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Not applicable Interventional

Open-label Safety Extension Study of Gevokizumab in Erosive Osteoarthritis of the Hand

NCT02293564
View directory record Official record
Conditions
Osteoarthritis
Interventions
gevokizumab
Drug
Lead sponsor
XOMA (US) LLC
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
28
States / cities
Tucson, Arizona • Little Rock, Arkansas • Roseville, California + 25 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Not applicable Interventional Results available

A Pilot Randomized Controlled Trial for Hand Osteoarthritis

NCT04784065
View directory record Official record
Conditions
Hand Osteoarthritis
Interventions
Hand orthosis
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
New York, New York • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Sep 27, 2026, 5:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Is Topical CBD Effective in Treating Thumb Joint Arthritis

NCT04611347
View directory record Official record
Conditions
CBD, Hand Osteoarthritis
Interventions
CBD, Shea Butter
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 27, 2026, 5:14 AM EDT