- Conditions
- Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
- Interventions
- DeNovo NT Natural Tissue Graft
- Other
- Lead sponsor
- Zimmer Orthobiologics, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 205 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 8
- States / cities
- Sacramento, California • Honolulu, Hawaii • Baltimore, Maryland + 5 more
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- Conditions
- Pilon Fractures
- Interventions
- Diagnostic Ankle Nano-Arthroscopy
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Osteochondral Lesions of Talus
- Interventions
- ankle arthroscopy with debridement and microfracture of the OLT, Bone Marrow Aspirate injection
- Procedure · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Chondral Defect, Articular Cartilage Defect
- Interventions
- autologous cultured chondrocytes on porcine collagen membrane, Bone Marrow Stimulation
- Biological · Procedure
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 17 Years to 65 Years
- Enrollment
- 309 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 4
- States / cities
- Washington D.C., District of Columbia • Wichita, Kansas • Houston, Texas + 1 more
- Conditions
- Osteochondral Lesion of Talus
- Interventions
- Microfracture with Bone Marrow Aspirate Concentrate, Microfracture
- Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania