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ClinicalTrials.gov public records Last synced Oct 9, 2026, 4:31 PM EDT

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Showing 97–120 of 207 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Osteopenia, Osteoporosis Clear all
Completed Phase 3 Interventional

Effects of Parathyroid Hormone in Men With Osteoporosis

NCT00000427
View directory record Official record
Conditions
Osteoporosis
Interventions
Parathyroid hormone, Alendronate
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
46 Years to 85 Years · Male only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 9, 2013 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 2 Interventional

Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy

NCT00165204
View directory record Official record
Conditions
Menopause, Postmenopausal Bone Loss, Breast Cancer
Interventions
Tibolone
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2007 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 2 Interventional Results available

A Study of LY2541546 in Women With Low Bone Mineral Density

NCT01144377
View directory record Official record
Conditions
Osteoporosis
Interventions
LY2541546, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years to 85 Years · Female only
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Gainesville, Georgia • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 9, 2026, 4:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of HIV Infection and Highly Active Antiretroviral Treatment (HAART) on Bone Homeostasis

NCT01020045
View directory record Official record
Conditions
HIV Infection, Osteopenia, Osteoporosis
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Oct 9, 2026, 4:31 PM EDT
Recruiting Phase 1 Interventional

Veverimer to Decrease Net Acid Excretion and Bone Resorption in Adults With Osteopenia

NCT07473713
View directory record Official record
Conditions
Osteopenia
Interventions
veverimer daily, veverimer every other day, Placebo
Drug · Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 9, 2026, 4:31 PM EDT
Completed No phase listed Observational

Bone Loss, Fractures, and Management of Bone Health in People With Stroke in Managed Rehabilitation Settings

NCT00462683
View directory record Official record
Conditions
Stroke, Anoxia, Brain Injury
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 6, 2012 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Comparison of Raloxifene and Lasofoxifene - A Randomized, Blinded Study of These Drugs and Placebo on Bone Loss

NCT00163137
View directory record Official record
Conditions
Osteoporosis
Interventions
lasofoxifene, raloxifene, Placebo
Drug
Lead sponsor
Ligand Pharmaceuticals
Industry
Eligibility
48 Years to 75 Years · Female only
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
72
States / cities
Albany, California • Berkeley, California • La Jolla, California + 49 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2011 · Synced Oct 9, 2026, 4:31 PM EDT
Active, not recruiting Phase 2 Interventional

A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS)

NCT06577935
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
AGA2118, Placebo
Drug · Other
Lead sponsor
Angitia Biopharmaceuticals
Industry
Eligibility
55 Years to 80 Years · Female only
Enrollment
379 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
Birmingham, Alabama • Gainesville, Georgia • Albuquerque, New Mexico + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Safety and Efficacy of BA058 (Abaloparatide) for Prevention of Fracture in Postmenopausal Women

NCT01343004
View directory record Official record
Conditions
Osteoporosis, Postmenopausal Osteoporosis
Interventions
Placebo, BA058 80 mcg, teriparatide
Drug
Lead sponsor
Radius Health, Inc.
Industry
Eligibility
50 Years to 85 Years · Female only
Enrollment
2,463 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
5
States / cities
Lakewood, Colorado • Miami, Florida • North Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Growth Hormone and Bone in Obesity

NCT01724489
View directory record Official record
Conditions
Obesity, Osteopenia
Interventions
Growth hormone, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 9, 2026, 4:31 PM EDT
Recruiting Not applicable Interventional

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

NCT06184646
View directory record Official record
Conditions
Bone Disease, Metabolic
Interventions
Prune
Dietary Supplement
Lead sponsor
San Diego State University
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Effectiveness of Soy Phytoestrogens to Prevent Bone Loss

NCT00665860
View directory record Official record
Conditions
Osteoporosis
Interventions
Placebo, Soy isoflavones
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
3
States / cities
Davis, California • Athens, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 2 Interventional Results available

Denosumab for Prevention of Post-Teriparatide Bone Loss in Premenopausal Women With IOP

NCT02049866
View directory record Official record
Conditions
Adult Idiopathic Generalized Osteoporosis
Interventions
Denosumab
Drug
Lead sponsor
Elizabeth Shane
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
2
States / cities
Omaha, Nebraska • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Results available

Models of Primary Osteoporosis Screening in Male Veterans

NCT04079868
View directory record Official record
Conditions
Osteoporosis, Osteopenia, Osteoporotic Fracture
Interventions
Bone Health Service Model
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
3,512 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Durham, North Carolina • Salt Lake City, Utah • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Results available

Wearable Vibration Device to Prevent Bone Loss in Postmenopausal Women--Aim 2

NCT03688282
View directory record Official record
Conditions
Osteopenia
Interventions
Wearable vibration belt, Sham, wearing belt
Device
Lead sponsor
Theranova, L.L.C.
Industry
Eligibility
Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 2 Interventional Results available

Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV)

NCT01228318
View directory record Official record
Conditions
HIV Infection, Bone Loss, Osteopenia, Osteoporosis
Interventions
Zoledronic acid
Drug
Lead sponsor
Emory University
Other
Eligibility
30 Years to 50 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 9, 2026, 4:31 PM EDT
Withdrawn Phase 4 Interventional

Pilot E2 for Hypogonadal Women With CFBD

NCT03724955
View directory record Official record
Conditions
Cystic Fibrosis Related Bone Disease
Interventions
Estradiol 2 mg, Placebo
Drug · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 3 Interventional Results available

Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis

NCT04064411
View directory record Official record
Conditions
Postmenopausal Osteoporosis
Interventions
abaloparatide, abaloparatide solid microstructured transdermal system
Combination Product
Lead sponsor
Radius Health, Inc.
Industry
Eligibility
50 Years to 85 Years · Female only
Enrollment
511 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
77
States / cities
Birmingham, Alabama • Anchorage, Alaska • Glendale, Arizona + 65 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 9, 2026, 4:31 PM EDT
Terminated No phase listed Observational

Proton Pump Inhibitor Therapy and Bone Density in Premature Infants

NCT00888017
View directory record Official record
Conditions
Osteopenia, Prematurity
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 23, 2013 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Forteo for the Treatment of Unexplained Osteoporosis in Premenopausal Women

NCT00697463
View directory record Official record
Conditions
Menopause, Fracture, Osteoporosis
Interventions
Teriparatide (PTH 1-34)
Drug
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 48 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Omaha, Nebraska • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Results available

Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

NCT00436917
View directory record Official record
Conditions
Breast Cancer, Osteoporosis
Interventions
zoledronic acid, Letrozole as adjuvant therapy
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Soy and Isoflavones Effect on Bone

NCT00668447
View directory record Official record
Conditions
Osteoporosis
Interventions
Soy Isolate, Control protein, Novasoy isoflavones, Placebo tablets
Dietary Supplement
Lead sponsor
United States Department of Agriculture (USDA)
Federal
Eligibility
65 Years and older · Female only
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2008 · Synced Oct 9, 2026, 4:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Potassium Citrate to Prevent Age Related Bone Loss

NCT00282126
View directory record Official record
Conditions
Osteoporosis
Interventions
Potassium citrate
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years to 90 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2014 · Synced Oct 9, 2026, 4:31 PM EDT
Completed No phase listed Observational

The Natural History of Injury-Related Disuse Osteopenia

NCT03868085
View directory record Official record
Conditions
Osteopenia
Interventions
dual energy x-ray absorptiometry
Diagnostic Test
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Oct 9, 2026, 4:31 PM EDT