- Conditions
- Acute Respiratory Tract Infection, Otitis Media, Pharyngitis, Acute Sinusitis
- Interventions
- Broad Implementation of Outpatient Stewardship (BIOS) intervention
- Behavioral
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 1,032 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 5
- States / cities
- Plantation, Florida • Cleveland, Ohio • Hershey, Pennsylvania + 1 more
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- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis, Tympanic Membrane Perforation, Otitis Media With Effusion, Cholesteatoma
- Interventions
- Not listed
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 20 Years to 89 Years
- Enrollment
- 320 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2020
- U.S. locations
- 2
- States / cities
- Portland, Oregon • Mountain Home, Tennessee
- Conditions
- Influenza, Otitis Media, Lower Resp Tract Infection, Encephalitic Infection, Myositis Viral, Fever
- Interventions
- Respiratory nasal swab
- Procedure
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 6 Months to 8 Years
- Enrollment
- 1,478 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Broomfield, Colorado
- Conditions
- Community-acquired Pneumonia, Acute Otitis Media, Pharyngitis
- Interventions
- Quasi experimental intervention
- Other
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- Not listed
- Enrollment
- 26,139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Otitis Media
- Interventions
- Simethicone, Placebo
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Cleft Palate, Tube Disorders Eustachian, Velopharyngeal Incompetence Due to Cleft Palate, Velopharyngeal Insufficiency
- Interventions
- EMST150
- Device
- Lead sponsor
- Noel Jabbour
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otitis Media With Effusion
- Interventions
- bilateral myringotomy, bilateral myringotomy and tubes, adenoidectomy
- Procedure
- Lead sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
- NIH
- Eligibility
- 24 Months to 47 Months
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 2007
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otitis Media With Effusion, Acute Otitis Media, Otitis Media
- Interventions
- Iontophoresis and tube placement
- Combination Product
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 6
- States / cities
- Louisville, Kentucky • Cherry Hill, New Jersey • New Brunswick, New Jersey + 3 more
- Conditions
- Otitis Externa
- Interventions
- Ciprofloxacin/Dexamethasone, Ciprodex (R), Placebo
- Drug
- Lead sponsor
- Par Pharmaceutical, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 455 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 27
- States / cities
- Tucson, Arizona • Jonesboro, Arkansas • Little Rock, Arkansas + 23 more
- Conditions
- Otitis Media
- Interventions
- Hyland's earache drops
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 6 Months to 11 Years
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 3
- States / cities
- Mercer Island, Washington • Renton, Washington • Seattle, Washington
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Unilateral, Hearing Loss, Sudden, Hearing Loss, Cochlear, Hearing Loss in Left Ear, Hearing Loss in Right Ear, Labyrinthitis
- Interventions
- Cochlear implantation
- Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Baltimore, Maryland • Bethesda, Maryland • Lutherville-Timonium, Maryland + 1 more
- Conditions
- Eustachian Tube Dysfunction, Chronic Otitis Media
- Interventions
- Not listed
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Otomycosis
- Interventions
- SVT-15652, Placebo
- Drug
- Lead sponsor
- Salvat
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 217 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Orangeburg, South Carolina
- Conditions
- Otitis Media, Urinary Tract Infection, Asthma, Head Injury
- Interventions
- patient-driven health IT product
- Procedure
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- Up to 12 Years
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Weymouth, Massachusetts
- Conditions
- Hunter Syndrome, Mucopolysaccharidosis II (MPS II)
- Interventions
- Idursulfase
- Biological
- Lead sponsor
- Shire
- Industry
- Eligibility
- 5 Years and older · Male only
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2008
- U.S. locations
- 16
- States / cities
- Phoenix, Arizona • Oakland, California • Denver, Colorado + 13 more
- Conditions
- Otitis Media
- Interventions
- Ear tube placement with the Hummingbird TTS
- Device
- Lead sponsor
- Preceptis Medical, Inc.
- Industry
- Eligibility
- 6 Months and older
- Enrollment
- 199 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 4
- States / cities
- Maple Grove, Minnesota • Minneapolis, Minnesota • Rochester, Minnesota
- Conditions
- Bilateral Middle Ear Effusion
- Interventions
- OTO-201
- Drug
- Lead sponsor
- Otonomy, Inc.
- Industry
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 5
- States / cities
- Fresno, California • Charlotte, North Carolina • Matthews, North Carolina + 2 more
- Conditions
- Acute Otitis Externa
- Interventions
- Ciprodex®, EXL CDOS (Ciprofloxacin 0.3% and Dexamethasone 0.1%) Sterile Otic Suspension
- Drug
- Lead sponsor
- Exela Pharma Sciences, LLC.
- Industry
- Eligibility
- 6 Months and older
- Enrollment
- 499 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 46
- States / cities
- Birmingham, Alabama • Mesa, Arizona • Jonesboro, Arkansas + 36 more
- Conditions
- Otitis Media
- Interventions
- Prescription Fill Status
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 240 participants
- Timeline
- 2004 – 2005
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Otitis Media
- Interventions
- ear pain counseling, language power counseling
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 12 Months to 15 Months
- Enrollment
- 310 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2015
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Acute Otitis Media
- Interventions
- Tympanostomy tube placement, Amoxicillin-Clavulanate and/or Ceftriaxone, Ofloxacin Otic
- Device · Drug
- Lead sponsor
- Alejandro Hoberman
- Other
- Eligibility
- 6 Months to 35 Months
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 2
- States / cities
- Washington D.C., District of Columbia • Pittsburgh, Pennsylvania
- Conditions
- Acute Otitis Media, Acute Sinusitis, Group A Streptococcal Pharyngitis
- Interventions
- Broad-spectrum antibiotics, Narrow-spectrum antibiotics
- Drug
- Lead sponsor
- Children's Hospital of Philadelphia
- Other
- Eligibility
- 6 Months to 12 Years
- Enrollment
- 2,472 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Acute Otitis Media
- Interventions
- Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution, Placebo Otic solution
- Drug
- Lead sponsor
- Currax Pharmaceuticals
- Industry
- Eligibility
- 2 Months to 12 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 10
- States / cities
- Mesa, Arizona • Tucson, Arizona • Bentonville, Arkansas + 5 more
- Conditions
- Otitis Media
- Interventions
- Acclarent Tympanostomy Tube Delivery System (TTDS).
- Device
- Lead sponsor
- Integra LifeSciences Corporation
- Industry
- Eligibility
- Not listed
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010
- U.S. locations
- 1
- States / cities
- Kirkland, Washington