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ClinicalTrials.gov public records Last synced Oct 14, 2026, 10:31 AM EDT

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Showing 553–576 of 2,314 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Otolaryngologic Disease Clear all
Completed Not applicable Interventional

PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer

NCT03455608
View directory record Official record
Conditions
Dysphagia
Interventions
RE-ACTIVE, PRO-ACTIVE EAT, PRO-ACTIVE EAT + EXERCISE
Behavioral
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
952 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
10
States / cities
Miami, Florida • Orlando, Florida • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional Results available

Xylitol Versus Saline in Chronic Sinusitis

NCT00924404
View directory record Official record
Conditions
Chronic Sinusitis
Interventions
Xylitol, Saline
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional Results available

Variability In Hearing Aid Outcomes In Older Adults

NCT02448706
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Hearing Aid Fitting A, Hearing Aid Fitting B
Device
Lead sponsor
Northwestern University
Other
Eligibility
54 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional

Does Wearing Hearing Aids Impact the Affective State of Older Adults With Hearing Loss in Their Daily Lives?

NCT06249685
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Sensorineural, Emotions, Stress Physiology
Interventions
Bilateral hearing devices
Device
Lead sponsor
University of Memphis
Other
Eligibility
50 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 14, 2026, 10:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluating the GN ReSound Relief App Using task-and Rest-based fMRI

NCT03888521
View directory record Official record
Conditions
Tinnitus, Subjective
Interventions
Resound Relief smartphone app
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 14, 2026, 10:31 AM EDT
Terminated No phase listed Observational

Electrode Placement and Audiologic Outcomes With the Advanced Bionics HiFocus L23 Electrode

NCT03858647
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 14, 2026, 10:31 AM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

NCT05506085
View directory record Official record
Conditions
Laryngeal Dystonia, Adductor Spastic Dysphonia of Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Striated Esophageal Motor Function Modulation in Health and Disease

NCT05708885
View directory record Official record
Conditions
Dysphagia, Esophageal
Interventions
Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction, Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 90 Years
Enrollment
557 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional

Project PAIR: Parent-implemented Articulation Intervention With Recast

NCT06936696
View directory record Official record
Conditions
Hearing Impaired Children
Interventions
Broad Target Speech Recast, Traditional Speech Therapy
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
4 Years to 10 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Completed No phase listed Observational

Oral Bacteria and Allergic Disease in Children

NCT00438646
View directory record Official record
Conditions
Asthma, Rhinitis, Eczema, Respiratory Sounds, Hypersensitivity
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
6 Years to 11 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 25, 2009 · Synced Oct 14, 2026, 10:31 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Results available

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

NCT05232851
View directory record Official record
Conditions
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Human Papillomavirus-Related Carcinoma, Locally Advanced Oropharyngeal Carcinoma, Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101, Pembrolizumab, Computed Tomography, FDG-Positron Emission Tomography, Biospecimen Collection, Biopsy
Biological · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Not listed No phase listed Observational

NF2 Natural History Consortium

NCT00004483
View directory record Official record
Conditions
Schwannoma, Vestibular, Neurofibromatosis 2, Meningioma
Interventions
Not listed
Lead sponsor
House Ear Institute
Other
Eligibility
5 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2005 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional

Anesthetic to Reduce Dysphagia After Anterior Cervical Discectomy and Fusion Surgery

NCT02376205
View directory record Official record
Conditions
Dysphagia
Interventions
bupivacaine hydrochloride 0.5% solution, 0.9% NaCl solution
Drug
Lead sponsor
Justin Parker Neurological Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 13, 2020 · Synced Oct 14, 2026, 10:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Computerized Vestibular Rehabilitation

NCT03589859
View directory record Official record
Conditions
Vestibular Diseases
Interventions
VOR Test, Computer Game, Nausea Scale
Diagnostic Test · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 14, 2026, 10:31 AM EDT
Completed No phase listed Observational

Early Detection of Barrett's Esophagus

NCT00081354
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
737 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional Results available

Lingual Endurance Exercise in Treating Post-Stroke Dysphagia

NCT05523973
View directory record Official record
Conditions
Dysphagia, Oral Phase, Stroke, Ischemic
Interventions
Lingual Endurance Training
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Phase 2 Interventional Results available

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

NCT04283669
View directory record Official record
Conditions
Neurofibromatosis 2, Progressive Vestibular Schwannoma (VS)
Interventions
Crizotinib
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
6 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Topical Treatment of Acute Otitis Media Through Tympanostomy Tubes (AOMT) and Its Effect on Microbial Flora

NCT01027494
View directory record Official record
Conditions
Acute Otitis Media
Interventions
Ciprofloxacin 0.3% and dexamethasone 0.1% otic suspension
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
6 Months to 4 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2013 · Synced Oct 14, 2026, 10:31 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome

NCT00732680
View directory record Official record
Conditions
Empty Nose Syndrome, Atrophic Rhinitis
Interventions
Botulinum Toxin Type A
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Phase 3 Interventional

A Safety and Bioequivalence of a Mometasone Nasal Spray, 50 mcg/Actuation Compared With Nasonex® Nasal Spray 50 mcg/Actuation in the Relief of the Symptoms of Seasonal Allergic Rhinitis (SAR)

NCT01673659
View directory record Official record
Conditions
Seasonal Allergic Rhinitis
Interventions
Mometasone furoate, Nasonex Nasal Spray, Placebo nasal spray
Drug
Lead sponsor
Padagis LLC
Industry
Eligibility
12 Years to 65 Years
Enrollment
1,220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional Results available

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

NCT03377270
View directory record Official record
Conditions
Head and Neck Cancer, Dysphagia
Interventions
Respiratory Swallow Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 14, 2026, 10:31 AM EDT
Completed Not applicable Interventional

Internet Auditory Rehabilitation: Follow-up to Adult Hearing Screening

NCT04122183
View directory record Official record
Conditions
Hearing Loss
Interventions
iManage (my hearing loss)
Other
Lead sponsor
University of Louisville
Other
Eligibility
45 Years to 85 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 14, 2026, 10:31 AM EDT
Enrolling by invitation Not applicable Interventional

Hearing Health Equity Through Accessible Research and Solutions for Korean Americans

NCT06803394
View directory record Official record
Conditions
Age-related Hearing Impairment, Personal Communication, Hearing Impairment, Hearing Loss, Community-dwelling Seniors, Korean
Interventions
K-HEARS Intervention, K-HEARS Sound Amplifier Intervention
Behavioral · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 14, 2026, 10:31 AM EDT
Terminated Phase 1 Interventional

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

NCT04272034
View directory record Official record
Conditions
Advanced Solid Tumors, MSI-H/dMMR Tumors, Cutaneous Squamous Cell Carcinoma, Urothelial Carcinoma, HCC, Cervical Cancer, Esophageal Squamous Cell Carcinoma, Merkel Cell Carcinoma, Small-cell Lung Cancer, Mesothelioma, PD-L1 Amplified Tumor (9p24.1), Nasopharyngeal Carcinoma, Cyclin-dependent Kinase 12 Mutated Tumors, Basal Cell Carcinoma (Unresectable or Metastatic), Sarcomatoid Renal Cell Carcinoma, Clear Cell Ovarian or Endometrial Carcinoma, Anal Carcinoma, Squamous Cell Penile Carcinoma, DNA Polymerase Epsilon Mutated Tumors (P286R and V411L)
Interventions
INCB099318
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Hackensack, New Jersey • Greenville, South Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 14, 2026, 10:31 AM EDT