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ClinicalTrials.gov public records Last synced Oct 9, 2026, 6:15 AM EDT

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Showing 73–96 of 2,308 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Otolaryngological Disease Clear all
Completed Phase 1 Interventional

Photodynamic Therapy Using HPPH in Treating Patients With Dysplasia, Cancer in Situ, or Invasive Cancer of the Larynx

NCT00675233
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
HPPH, laser therapy
Drug · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Computer-Assisted Scheduling of Nicotine Inhaler Use in Participants Who Plan to Stop Smoking

NCT00021138
View directory record Official record
Conditions
Esophageal Cancer, Head and Neck Cancer, Lung Cancer
Interventions
smoking cessation intervention, nicotine
Behavioral · Drug
Lead sponsor
Personal Improvement Computer Systems
Other
Eligibility
18 Years to 67 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Reston, Virginia
Source: ClinicalTrials.gov public record
Updated May 15, 2013 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis

NCT03290248
View directory record Official record
Conditions
Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen, Healthy Volunteers
Interventions
B244 suspension, Vehicle
Biological
Lead sponsor
AOBiome LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tustin, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2022 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1 Interventional Results available

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

NCT02113878
View directory record Official record
Conditions
Carcinoma, Squamous Cell of Head and Neck, HPV Positive Oropharyngeal Squamous Cell Carcinoma, Hypopharyngeal Cancer, Early Invasive Cervical Squamous Cell Carcinoma, Carcinoma of Larynx, Cancer of Nasopharynx
Interventions
BKM120, Cisplatin, Intensity-modulated radiotherapy (IMRT)
Drug · Radiation
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2024 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Phase 2 Interventional Results available

Phase II Trial Evaluating Elimination of Radiation Therapy

NCT00593840
View directory record Official record
Conditions
Cancer of the Larynx
Interventions
Intensity modulated radiation therapy
Radiation
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

The EarLens System Long Term Safety and Efficacy Definitive Multi-Center Study

NCT02042404
View directory record Official record
Conditions
Hearing Impairment
Interventions
Sound amplification provided via EarLens System.
Device
Lead sponsor
EarLens Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Menlo Park, California • San Jose, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

NCT01961297
View directory record Official record
Conditions
Spasmodic Dysphonia, Voice Tremor
Interventions
Sodium oxybate
Drug
Lead sponsor
Kristina Simonyan
Other
Eligibility
21 Years to 80 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis

NCT04769596
View directory record Official record
Conditions
Chronic Rhinitis
Interventions
NEUROMARK™ System, Sham Device
Device
Lead sponsor
Neurent Medical
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
8
States / cities
Birmingham, Alabama • Roseville, California • Colorado Springs, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1 Interventional

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

NCT00036790
View directory record Official record
Conditions
Breast Cancer, Chronic Myeloproliferative Disorders, Colorectal Cancer, Head and Neck Cancer, Leukemia, Lung Cancer, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic/Myeloproliferative Diseases, Prostate Cancer, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
doxorubicin hydrochloride, motexafin gadolinium
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

CROS Application in CI

NCT03243097
View directory record Official record
Conditions
Hearing Loss
Interventions
Phase I - Standard Microphone Cros Input, Phase II - Automatic directional microphone Cros Input, Phase III - No Cros Input
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Evaluation of the OtoBand in Subjects With Self-reported Vertigo to Reduce Severity of Vertigo in a Real-world Setting

NCT04869020
View directory record Official record
Conditions
Vertigo
Interventions
Otoband, Sham A, Sham B
Device
Lead sponsor
Otolith Labs
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional

The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors

NCT05798780
View directory record Official record
Conditions
Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer, Larynx Cancer
Interventions
ENHANCE Intervention - Exercise and Nutrition, ENHANCE Intervention - Nutrition Only
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Not yet recruiting Phase 1 Interventional

Topical TOR-582 Treatment of Epistaxis in HHT

NCT07667413
View directory record Official record
Conditions
Hereditary Hemorrhagic Telangiectasia (HHT), Epistaxis
Interventions
Topical sirolimus ointment
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Efficacy of a Drug Eluting Slim Modiolar Electrode Array

NCT06598059
View directory record Official record
Conditions
Hearing Loss
Interventions
Cochlear implant, Dexamethasone
Device · Drug
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Englewood, Colorado • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study to Evaluate Ear Acupressure Effects in Treating Seasonal Allergic Rhinitis

NCT01921348
View directory record Official record
Conditions
Seasonal Allergic Rhinitis
Interventions
acupressure pellets
Device
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional

Non-Invasive Neurofeedback Training to Alleviate Tinnitus Distress

NCT07788638
View directory record Official record
Conditions
Tinnitus Aggravated, Tinnitus, Tinnitus, Subjective
Interventions
neurofeedback-guided brain connectivity modulation, sham neurofeedback-guided brain connectivity modulation
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 1 Interventional

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma

NCT01064921
View directory record Official record
Conditions
Stage III Squamous Cell Carcinoma of the Oropharynx, Stage IV Squamous Cell Carcinoma of the Oropharynx
Interventions
vorinostat, cisplatin, radiation therapy, Correlative Studies
Drug · Radiation · Procedure
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 9, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia

NCT06493825
View directory record Official record
Conditions
Tinnitus, Misophonia
Interventions
Aurora Mindfulness app versus sham
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nasotracheal Intubation Over a Bougie

NCT03003455
View directory record Official record
Conditions
Nasotracheal Intubation, Nasal Bleeding
Interventions
Nasotracheal intubation over a bougie, Conventional Nasotracheal Intubation
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
8 Years to 99 Years
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 28, 2016 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users Pilot Study (Oticon Pilot Study)

NCT04469946
View directory record Official record
Conditions
Hearing Impairment, Sensorineural Hearing Loss, Bilateral
Interventions
Oticon OpenSound Navigator speech enhancement algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)

NCT01129141
View directory record Official record
Conditions
Tinnitus
Interventions
Tele-PTM, Wait List Control
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Oct 9, 2026, 6:15 AM EDT
Completed No phase listed Observational

Post-extubation Assessment of Laryngeal Symptoms and Severity

NCT03726086
View directory record Official record
Conditions
Intubation, Intratracheal, Critical Illness, Mechanical Ventilation Complication, Complication of Ventilation Therapy
Interventions
laryngoscopy
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Cochlear Implant With Dexamethasone Eluting Electrode Array

NCT04750642
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss
Interventions
CI632D, CI632
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
4
States / cities
Englewood, Colorado • Iowa City, Iowa • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Oct 9, 2026, 6:15 AM EDT
Completed Phase 2 Interventional Results available

rTMS To The Dorsolateral Prefrontal Cortex For Patients With Subjective Idiopathic Tinnitus. A Pilot Study

NCT00886938
View directory record Official record
Conditions
Tinnitus
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), pilot study
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 16, 2014 · Synced Oct 9, 2026, 6:15 AM EDT