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ClinicalTrials.gov public records Last synced Oct 15, 2026, 5:39 PM EDT

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Showing 601–624 of 2,312 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Otorhinolaryngologic Disease Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Otoprotection With SPI-1005 for Prevention of Temporary Auditory Threshold Shift

NCT01444846
View directory record Official record
Conditions
Temporary Auditory Threshold Shift
Interventions
SPI-1005 Low dose, SPI-1005 Middle dose, SPI-1005 High dose, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 31 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 1Phase 2 Interventional

Complementary/Alternative Medicine for Abnormality in the Vestibular (Balance) System

NCT00032383
View directory record Official record
Conditions
Vestibular Neuronitis, Vestibulopathy
Interventions
Tai Chi
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 22, 2007 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 3 Interventional Results available

House Dust Mite Allergy Trial In Children

NCT04145219
View directory record Official record
Conditions
Allergic Rhinitis Due to Dermatophagoides Farinae, Allergic Rhinitis Due to Dermatophagoides Pteronyssinus, Allergic Rhinitis Due to House Dust Mite
Interventions
Sublingual allergy immunotherapy tablet, Placebo
Biological · Other
Lead sponsor
ALK-Abelló A/S
Industry
Eligibility
5 Years to 11 Years
Enrollment
1,460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
29
States / cities
Huntington Beach, California • Los Angeles, California • San Diego, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 4 Interventional Results available

A 6 Month Safety Study Of Ciclesonide Nasal Aerosol (Zetonna®) And Ciclesonide Nasal Spray (Omnaris®) In Subjects 12 Years And Older With Perennial Allergic Rhinitis (PAR)

NCT01654536
View directory record Official record
Conditions
Perennial Allergic Rhinitis
Interventions
ciclesonide nasal aerosol, ciclesonide nasal spray
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
12 Years and older
Enrollment
737 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
31
States / cities
Mission Viejo, California • Orange, California • San Diego, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Open-canal Behind-the-Ear Hearing Aids and Traditional In-the-ear Hearing Aids.

NCT00727909
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing Aid Treatments
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
3
States / cities
Bay Pines, Florida • Mountain Home, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 10, 2014 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lyric Self-replacement Clinical Investigation

NCT05349981
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Lyric self-replacement procedure
Device
Lead sponsor
Sonova AG
Industry
Eligibility
22 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
8
States / cities
San Francisco, California • New York, New York • Greensboro, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 15, 2026, 5:39 PM EDT
Completed No phase listed Observational

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

NCT01222728
View directory record Official record
Conditions
Neoplasms, Nervous System Disease, Vestibular Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 15, 2026, 5:39 PM EDT
Recruiting No phase listed Observational

Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers

NCT00900419
View directory record Official record
Conditions
Esophageal Cancer, Head and Neck Cancer, Lung Cancer, Precancerous Condition
Interventions
immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology, biopsy
Other · Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 90 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Oct 15, 2026, 5:39 PM EDT
Completed No phase listed Observational Results available

Qualitative Analysis of Subject Experience of Nasal Polyps

NCT03221192
View directory record Official record
Conditions
Nasal Polyps
Interventions
VAS questionnaire, SNOT-22 questionnaire, Data capture app
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps

NCT01732536
View directory record Official record
Conditions
Chronic Sinusitis, Nasal Polyps
Interventions
S8 Sinus Implant, Sham procedure, Mometasone furoate nasal spray
Drug · Procedure
Lead sponsor
Intersect ENT
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
19
States / cities
Atherton, California • Los Angeles, California • Sacramento, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 15, 2026, 5:39 PM EDT
Recruiting Not applicable Interventional

Characterizing the Impact of Presbyphonia on Social Interaction

NCT06441136
View directory record Official record
Conditions
Presbyphonia
Interventions
PhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index, The Edmonton Frail Scale, Vocal Effort Scale, Montreal Cognitive Assessment, Voice Handicap Index-10, Voice Problem Impact Scales, Cough Severity Index, Laryngoscopy, Acoustic, perceptual, and aerodynamic assessments
Other · Procedure
Lead sponsor
Matthew R. Hoffman
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 2 Interventional

The Effect of Nasal Carbon Dioxide (CO2) in the Symptomatic Treatment of Seasonal Allergic Rhinitis

NCT00917111
View directory record Official record
Conditions
Seasonal Allergic Rhinitis
Interventions
Nasal CO2, Inactive Placebo Gas
Drug
Lead sponsor
Capnia, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Oct 15, 2026, 5:39 PM EDT
Enrolling by invitation Not applicable Interventional

Harnessing Digital Medicine to Improve Allergic Rhinitis Management in Primary Care (DMAR)

NCT06603935
View directory record Official record
Conditions
Allergic Rhinitis, Sinusitis
Interventions
QHSLab Digital Tools (AME and ARIS)
Other
Lead sponsor
QHSLab, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 1 Interventional

OTO-104 for Meniere's Disease

NCT01084525
View directory record Official record
Conditions
Meniere's Disease
Interventions
OTO-104 (steroid) 3 mg, Placebo, OTO-104 (steroid) 12 mg
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Colorado Springs, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Not applicable Interventional

Expanded Indications in the MED-EL Pediatric Cochlear Implant Population

NCT03900897
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
MED-EL SYNCHRONY PIN Cochlear Implant, Cochlear Implant
Device · Other
Lead sponsor
Med-El Corporation
Industry
Eligibility
7 Months to 5 Years
Enrollment
247 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
8
States / cities
Oakland, California • Miami, Florida • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 2 Interventional

Effects of Age and Age-Related Diseases on Swallowing

NCT00038350
View directory record Official record
Conditions
Dysphagia
Interventions
Lingual Strengthening
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
65 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 6, 2008 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 2 Interventional Results available

Manuka Honey in Preventing Esophagitis-Related Pain in Patients Receiving Chemotherapy and Radiation Therapy For Lung Cancer

NCT01262560
View directory record Official record
Conditions
Dysphagia, Lung Cancer, Pain, Esophagitis
Interventions
Manuka honey in liquid form, Manuka honey in lozenge form, Standard supportive care
Drug
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
59
States / cities
Mobile, Alabama • San Francisco, California • Stanford, California + 50 more
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maximizing Language Development in Children With Hearing Loss

NCT01963468
View directory record Official record
Conditions
Hearing Loss
Interventions
Early language intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
6 Months to 18 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 15, 2026, 5:39 PM EDT
Completed No phase listed Observational

Assessment of Treatment Response of Nasopharyngeal Cancer Using Simultaneous 18F-FDG-PET and MRI

NCT03656250
View directory record Official record
Conditions
Nasopharyngeal Cancer
Interventions
PET/CT scans
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 15, 2026, 5:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy

NCT01358097
View directory record Official record
Conditions
Head and Neck Cancer, Oropharyngeal Cancer, Human Papillomavirus, Squamous Cell Cancer
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2014 · Synced Oct 15, 2026, 5:39 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Dual-Task Cost in Bilateral Hearing Loss

NCT05540535
View directory record Official record
Conditions
Bilateral Hearing Loss, Healthy Aging
Interventions
Gait assessment, Cognitive assessment
Other
Lead sponsor
New York University
Other
Eligibility
40 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 15, 2026, 5:39 PM EDT
Active, not recruiting No phase listed Observational

Utility of Advanced Ultrasound Otoscope In The Diagnosis of AOM

NCT06429709
View directory record Official record
Conditions
Otitis Media Recurrent, Middle Ear Infection, Ear Infection
Interventions
Advanced Ultrasound Otoscope
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
0 Years to 12 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 15, 2026, 5:39 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of AkPharma's Calcium Glycerophosphate Nasal Spray Wash

NCT01647633
View directory record Official record
Conditions
Allergic Rhinitis
Interventions
Calcium Glycerophosphate Nasal Spray Wash
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 25, 2015 · Synced Oct 15, 2026, 5:39 PM EDT
Active, not recruiting Not applicable Interventional

In-Office Clinical Study of the Solo+ TTD

NCT05741333
View directory record Official record
Conditions
Ear Infection, Otitis Media
Interventions
Solo+ Tympanostomy Tube Device (Solo+ TTD)
Device
Lead sponsor
AventaMed DAC
Industry
Eligibility
6 Months to 13 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
7
States / cities
Alexander City, Alabama • Huntsville, Alabama • Opelika, Alabama + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 15, 2026, 5:39 PM EDT