- Conditions
- Opioid Use, Stimulant Use
- Interventions
- harm reduction intervention
- Behavioral
- Lead sponsor
- Brittany Miller-Roenigk
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 3
- States / cities
- Louisville, Kentucky • Cincinnati, Ohio
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Showing 1–24
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- Conditions
- Accidental Overdose of Opiate
- Interventions
- Overdose prevention resources, Overdose prevention education
- Other · Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
- Interventions
- More Individualized Care: Assessment and Recovery through Engagement (MI-CARE)
- Behavioral
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 805 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Indianapolis, Indiana • Seattle, Washington
- Conditions
- Opioid Use Disorder
- Interventions
- PRC supported text + AI driven CSDH-enhanced text, AI driven CSDH-enhanced text only, Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- Friends Research Institute, Inc.
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Respiratory Insufficiency, Opioid Overdose, Hypoventilation
- Interventions
- Trachea Sound Sensor (TSS)
- Device
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Opioid Overdose
- Interventions
- Extensive training
- Other
- Lead sponsor
- New York State Psychiatric Institute
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 405 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Accidental Overdose of Opiate
- Interventions
- Take home rapid drug test
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse, Substance Abuse, Opioid Use, Unspecified, Opioid Dependence, Drug Overdose
- Interventions
- TTIP-PRO
- Behavioral
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio
- Conditions
- Opioid Overdose
- Interventions
- Observation only
- Other
- Lead sponsor
- Member Companies of the Opioid PMR Consortium
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 808,455 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 4
- States / cities
- Wilmington, Delaware • Boston, Massachusetts • Portland, Oregon + 1 more
- Conditions
- Opioid Overdose
- Interventions
- Enhanced Overdose Education (EOE), Standard education
- Behavioral
- Lead sponsor
- Hartford Hospital
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 2
- States / cities
- Hartford, Connecticut
- Conditions
- Opiate Abuse, Opiate Overdose, Opioid-use Disorder
- Interventions
- Peer Addiction Counseling
- Behavioral
- Lead sponsor
- Prisma Health-Upstate
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Greenville, South Carolina
- Conditions
- Opioid Overdose
- Interventions
- Nalmefene HCl injection, Naloxone HCl intranasal
- Drug
- Lead sponsor
- Purdue Pharma LP
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Medication Abuse, Harm Reduction, Opioid Overdose, Opioid Prescribing
- Interventions
- Naloxone Co-prescribing Clinical Decision Support (CDS)
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 12 Years to 89 Years
- Enrollment
- 200,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
- Interventions
- TRTME
- Behavioral
- Lead sponsor
- T. John Winhusen, PhD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Drug Overdose, Opioid-Related Disorders, Drug Addiction, Drug Abuse, Substance Abuse
- Interventions
- Peer Intervention, naloxone nasal spray kit, Personally-tailored opioid overdose prevention education (information packet)
- Behavioral · Drug
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Opioid Overdose
- Interventions
- Opioids and Police Safety Occupational Risk Reduction Training (OPS), Opioids and Police Safety Occupational Risk Reduction Training (COVID)
- Behavioral
- Lead sponsor
- New York University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 333 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Opiate Overdose, Fentanyl Overdose, Harm Reduction
- Interventions
- Fentanyl Test Strips
- Behavioral
- Lead sponsor
- Nationwide Children's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 653 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Opioid Overdose
- Interventions
- UnityPhilly app
- Other
- Lead sponsor
- Drexel University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 450 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Harm Reduction, Naloxone, Opioid Overdose
- Interventions
- VENDY
- Behavioral
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- Not listed
- Enrollment
- 4,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Frisco, Colorado • Pueblo, Colorado
- Conditions
- Mental Health Disorders, Substance Use Disorders
- Interventions
- Full MISSION, Linkage Only Delivered by a Peer Specialist
- Behavioral
- Lead sponsor
- University of Massachusetts, Worcester
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 208 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Worcester, Massachusetts
- Conditions
- Opioid Overdose
- Interventions
- Nalmefene Hydrochloride
- Drug
- Lead sponsor
- Opiant Pharmaceuticals Inc
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Opioid-Related Disorders, Drug Overdose
- Interventions
- REBOOT
- Behavioral
- Lead sponsor
- San Francisco Department of Public Health
- Government
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 268 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 2
- States / cities
- San Francisco, California • Boston, Massachusetts
- Conditions
- Drug Overdose, Opioid Related Disorders
- Interventions
- Therapist-led brief intervention (TBI)
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Waterford, Michigan
- Conditions
- Opioid Overdose
- Interventions
- Educational Webinar, Resources, Reminders
- Behavioral
- Lead sponsor
- Auburn University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Auburn, Alabama