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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:27 PM EDT

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Showing 121–144 of 241 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Overweight/Obese Population Clear all
Active, not recruiting Phase 2 Interventional

Study to Evaluate HM15275 in Obese or Overweight Subjects Without Diabetes Mellitus

NCT07205900
View directory record Official record
Conditions
Obese, Obesity
Interventions
HM15275, Placebo of HM15275
Drug
Lead sponsor
Hanmi Pharmaceutical Company Limited
Industry
Eligibility
18 Years to 75 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
14
States / cities
Chula Vista, California • Oak Lawn, Illinois • Ames, Iowa + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Trial to Assess Bioavailability of AMG 133 in Participants With Overweight or Obesity

NCT07717814
View directory record Official record
Conditions
Overweight and Obesity
Interventions
AMG 133 (frozen liquid), AMG 133 (liquid)
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Anaheim, California • Daytona Beach, Florida • Dallas, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 3 Interventional Results available

BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management

NCT00603902
View directory record Official record
Conditions
Obesity
Interventions
Lorcaserin 10 mg once daily (QD), Lorcaserin 10 mg twice a day (BID), Matching Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
4,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 3 Interventional Results available

Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With Obesity

NCT02918279
View directory record Official record
Conditions
Metabolism and Nutrition Disorder, Obesity
Interventions
Liraglutide, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
12 Years to 17 Years
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
13
States / cities
Meridian, Idaho • Baton Rouge, Louisiana • Baltimore, Maryland + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2020 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Efficacy of a Strength Training Intervention on Exercise Adherence and Weight Among Pre-Menopausal Women

NCT05426070
View directory record Official record
Conditions
Physical Inactivity, Obesity
Interventions
Strength training-based exercise
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years to 50 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Oct 20, 2026, 11:27 PM EDT
Completed No phase listed Observational

Variability of Physical Assessments in an Older Population That is Overweight or Obese

NCT05174923
View directory record Official record
Conditions
Obesity, Aging
Interventions
Short Performance Physical Battery (SPPB Test), 30 Second Chair Stand Test (30CST), Hand grip dynamometry
Behavioral
Lead sponsor
Versanis Bio, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Jacksonville, Florida • Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Translating Neuroscience to Population Health

NCT03976427
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Guided Imagery
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Cafeteria Based Study of Weight Gain Prevention

NCT00573482
View directory record Official record
Conditions
Obesity, Overweight
Interventions
REDE, control
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
21 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2010 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 2 Interventional

A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight

NCT06683508
View directory record Official record
Conditions
Obesity, Overweight
Interventions
LY3549492, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
49
States / cities
Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 43 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition Intervention and Play Group Exercise for Low-income Latinas

NCT00454948
View directory record Official record
Conditions
Obesity
Interventions
Home-based nutrition sessions and play group exercise, Group-based nutrition sessions and mail-out activities
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 1 Interventional

To Assess the Effect of Lorcaserin Hydrochloride on Energy Metabolism and Food Intake

NCT00829140
View directory record Official record
Conditions
Obesity
Interventions
Placebo, Lorcaserin 10mg BID
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Oct 20, 2026, 11:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Obesity Group Visits. A Novel Way to Approach the Obesity Epidemic in an Inner-City Setting

NCT04725058
View directory record Official record
Conditions
Obesity
Interventions
Medical Group Visit, Dietitian Individual Visit
Other
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 90 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults

NCT00745251
View directory record Official record
Conditions
Sleep Apnea
Interventions
VI-0521, placebo
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
30 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 5, 2012 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety of Rimonabant on Weight Loss and Frequency of Binge Episodes in Obese Patients

NCT00481975
View directory record Official record
Conditions
Obesity, Eating Disorders
Interventions
rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 70 Years
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 7, 2009 · Synced Oct 20, 2026, 11:27 PM EDT
Active, not recruiting Not applicable Interventional

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

NCT01047735
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
Procedure · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
25 Years to 55 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

The Effect of Phentermine and B12 on Weight Loss Among Obese Patients

NCT01719185
View directory record Official record
Conditions
Obesity, Hypertension
Interventions
Phentermine and B12, Phentermine
Drug
Lead sponsor
Dr. Michael Lang
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2015 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional

The Retrain Your Brain for Healthy Eating Study

NCT05203718
View directory record Official record
Conditions
Obesity
Interventions
Food Response Training (FRT)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 20, 2026, 11:27 PM EDT
Completed No phase listed Observational

Comparison of Obesity Alleles Among Diverse Demographic Patients

NCT01396096
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
Not listed
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 2 Interventional Results available

Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists

NCT06640972
View directory record Official record
Conditions
Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
Interventions
RDX-002, Placebo
Drug
Lead sponsor
Response Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Active and Healthy Families

NCT02044705
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Active and Healthy Families
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
5 Years to 12 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Pittsburg, California • San Pablo, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2015 · Synced Oct 20, 2026, 11:27 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Treating Obesity in Underserved Overweight Populations

NCT00373230
View directory record Official record
Conditions
Overweight
Interventions
telemedicine
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Danville, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Oct 20, 2026, 11:27 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Metabolic Syndrome in an Elderly Population is More Linked to Insulin Resistance Than to Obesity

NCT00873964
View directory record Official record
Conditions
Metabolic Syndrome in the Elderly
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
60 Years to 80 Years
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 30, 2012 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 1 Interventional

A Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous Presentations

NCT07313761
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Maridebart Cafraglutide
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 60 Years
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Anaheim, California • Los Alamitos, California • Miami, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 20, 2026, 11:27 PM EDT
Completed Phase 2 Interventional Results available

Effect of GLP-1 Analogue ROSE-010 on Appetite in Overweight and Obese Subjects

NCT06621017
View directory record Official record
Conditions
Obesity; Overweight
Interventions
ROSE-010 99 mcg, Placebo, ROSE-010 150 mcg
Drug
Lead sponsor
Rose Pharma Inc
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 20, 2026, 11:27 PM EDT